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== 2024.04.12 ==
=== Proteomics ===
'''Proteomics''' is the large-scale study of [https://en.wikipedia.org/wiki/Protein proteins].<sup id="cite_ref-pmid9740045_1-0">[https://en.wikipedia.org/wiki/Proteomics#cite_note-pmid9740045-1 [1]]</sup><sup id="cite_ref-pmid10189717_2-0">[https://en.wikipedia.org/wiki/Proteomics#cite_note-pmid10189717-2 [2]]</sup> Proteins are vital parts of living organisms, with many functions such as the formation of structural fibers of [https://en.wikipedia.org/wiki/Muscle_tissue muscle tissue], enzymatic digestion of food, or synthesis and replication of [https://en.wikipedia.org/wiki/DNA DNA]. In addition, other kinds of proteins include [https://en.wikipedia.org/wiki/Antibodies antibodies] that protect an organism from infection, and [https://en.wikipedia.org/wiki/Hormones hormones] that send important signals throughout the body. The [https://en.wikipedia.org/wiki/Proteome proteome] is the entire set of proteins produced or modified by an organism or system. Proteomics enables the identification of ever-increasing numbers of proteins. This varies with time and distinct requirements, or stresses, that a cell or organism undergoes.<sup id="cite_ref-3">[https://en.wikipedia.org/wiki/Proteomics#cite_note-3 [3]]</sup> Proteomics is an interdisciplinary domain that has benefited greatly from the genetic information of various genome projects, including the [https://en.wikipedia.org/wiki/Human_Genome_Project Human Genome Project].<sup id="cite_ref-4">[https://en.wikipedia.org/wiki/Proteomics#cite_note-4 [4]]</sup> It covers the exploration of proteomes from the overall level of protein composition, structure, and activity, and is an important component of [https://en.wikipedia.org/wiki/Functional_genomics functional genomics]. ''Proteomics'' generally denotes the large-scale experimental analysis of proteins and proteomes, but often refers specifically to [https://en.wikipedia.org/wiki/Protein_purification protein purification] and [https://en.wikipedia.org/wiki/Mass_spectrometry mass spectrometry]. Indeed, mass spectrometry is the most powerful method for analysis of proteomes, both in large samples composed of millions of cells<sup id="cite_ref-5">[https://en.wikipedia.org/wiki/Proteomics#cite_note-5 [5]]</sup> and in single cells.<sup id="cite_ref-6">[https://en.wikipedia.org/wiki/Proteomics#cite_note-6 [6]]</sup><sup id="cite_ref-7">[https://en.wikipedia.org/wiki/Proteomics#cite_note-7 [7]]</sup><br/> <br/> <br/> <br/> <br/> <br/> <br/> <br/> <br/> <br/> [https://biolecture.org/Main_Page Main Page] » [https://biolecture.org/UNIST_Geromics_course UNIST Geromics course] » [https://biolecture.org/Geromics_Course_Students_Folder_2024 Geromics Course Students Folder 2024] » [https://biolecture.org/HyoungJinChoi_2024_Geromics_Course HyoungJinChoi 2024 Geromics Course] » [https://biolecture.org/Summary_class_Geromics_2024_HyoungJinChoi Summary class Geromics 2024 HyoungJinCho]