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| <div style="vertical-align: baseline; background: white; margin: 4.5pt 0cm; line-height: 13.5pt"><b><font size="6"><i><span style="font-size: 11pt; background: white; color: black; serif: ">BMC Genomics</span></i><span style="font-size: 11pt; background: white; color: black; serif: ">. </span><span style="font-size: 11pt; background: white; color: red; serif: ">2012 Sep </span><span style="font-size: 11pt; background: white; color: black; serif: ">12;13:473. doi: 10.1186/1471-2164-13-473.</span></font></b></div> | | <div style="vertical-align: baseline; background: white; margin: 4.5pt 0cm; line-height: 13.5pt"><b><font size="6"><i><span style="font-size: 11pt; background: white; color: black; serif: ">BMC Genomics</span></i><span style="font-size: 11pt; background: white; color: black; serif: ">. </span><span style="font-size: 11pt; background: white; color: red; serif: ">2012 Sep </span><span style="font-size: 11pt; background: white; color: black; serif: ">12;13:473. doi: 10.1186/1471-2164-13-473.</span></font></b></div> |
| <div style="margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all"> </div> | | <div style="margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all"> </div> |
− | <div style="margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all"><span style="font-size: 12pt; color: black; line-height: 160%">Weekly Schedule</span></div> | + | <div style="margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all">[[Jong Bhak's Genomics Syllabus]]</div> |
− | <p>
| + | <div style="margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all"> </div> |
− | <table border="0" style="border-collapse: collapse" cellspacing="0" cellpadding="0">
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− | <tbody>
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− | <tr style="height: 14.7pt">
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− | <td style="border-top: black 1pt solid; height: 14.7pt; border-right: black 1pt solid; width: 40.8pt; background: rgb(214,214,214); border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; border-image: none" width="68">
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− | <div style="text-align: center; margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 160%"><font size="2">Week</font></span></div>
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− | </td>
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− | <td style="border-top: black 1pt solid; height: 14.7pt; border-right: black 1pt solid; width: 410.2pt; background: rgb(214,214,214); border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; border-image: none" width="684">
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− | <div style="text-align: center; margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 160%"><font size="2">Contents</font></span></div>
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− | </td>
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− | </tr>
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− | <tr style="height: 35.65pt">
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− | <td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
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− | <div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">01</font></span></div>
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− | </td>
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− | <td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
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− | <div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"> </div>
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− | <div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> (Course orientation, Self-Cricial Evaluation: SCE), Homework, Presentation, and Research</font></span></div>
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− | <div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font></span></div>
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− | </td>
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− | </tr>
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− | <tr style="height: 35.65pt">
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− | <td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
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− | <div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">02</font></span></div>
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− | </td>
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− | <td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
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− | <div style="text-align: left; margin: 0cm 0cm 8pt; text-indent: 5pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> Chemistry and Biochemistry of Genomics</font></span></div>
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− | <div style="text-align: left; margin: 0cm 0cm 8pt; text-indent: 5pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> [[Sequencing]], [[PCR]], </font></span></div>
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− | <div style="text-align: left; margin: 0cm 0cm 8pt; text-indent: 5pt; -ms-word-break: keep-all" align="left"> </div>
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− | </td>
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− | </tr>
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− | <td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
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− | <div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">03</font></span></div>
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− | </td>
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− | <td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
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− | <div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> What is reference?</font></span></div>
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− | <div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> [[Alignment]]</font></span></div>
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− | <div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"> </div>
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− | </td>
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− | </tr>
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− | <td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
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− | <div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">04</font></span></div>
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− | </td>
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− | <td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
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− | <div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"> </div>
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− | </td>
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− | </tr>
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− | <tr style="height: 35.65pt">
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− | <td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
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− | <div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">05</font></span></div>
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− | </td>
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− | <td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
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− | <div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">What is Information?</font></span></div>
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− | <div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> Informatics</font></span></div>
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− | </td>
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− | <tr style="height: 35.65pt">
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− | <td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
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− | <div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">06</font></span></div>
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− | </td>
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− | <td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
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− | <div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">What is Programming?</font></span></div>
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− | <div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> Perl, Bioperl</font></span>, Algorithm</div>
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− | </td>
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− | </tr>
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− | <tr style="height: 35.65pt">
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− | <td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
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− | <div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">07</font></span></div>
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− | </td>
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− | <td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
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− | <div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">What is Bioinformatics? </font></span></div>
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− | <div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> Principles of Bioinformatics</font></span></div>
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− | </td>
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− | </tr>
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− | <tr style="height: 35.65pt">
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− | <td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
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− | <div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">08</font></span></div>
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− | </td>
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− | <td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
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− | <div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">What is Omics?</font></span></div>
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− | <div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> Various omics</font></span></div>
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− | </td>
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− | </tr>
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− | <tr style="height: 35.65pt">
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− | <td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
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− | <div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">09</font></span></div>
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− | </td>
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− | <td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
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− | <div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">What is Genomics?</font></span></div>
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− | </td>
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− | </tr>
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− | <tr style="height: 35.65pt">
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− | <td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
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− | <div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">10</font></span></div>
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− | </td>
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− | <td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
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− | <div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">What is Evolution?</font></span></div>
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− | <div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> Darwinian evolution</font></span></div>
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− | </td>
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− | </tr>
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− | <tr style="height: 35.65pt">
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− | <td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
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− | <div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">11</font></span></div>
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− | </td>
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− | <td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
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− | <div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">What is Sequence?</font></span></div>
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− | </td>
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− | </tr>
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− | <tr style="height: 35.65pt">
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− | <td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
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− | <div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">12</font></span></div>
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− | </td>
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− | <td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
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− | <div style="text-align: left; margin: 0cm 0cm 8pt; text-indent: 5pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2">What is Cancer?</font></span></div>
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− | </td>
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− | </tr>
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− | <tr style="height: 35.65pt">
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− | <td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
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− | <div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">13</font></span></div>
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− | </td>
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− | <td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
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− | <div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">What is Aging?</font></span></div>
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− | <div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> Measuring aging</font></span></div>
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− | <td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
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− | <div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">14</font></span></div>
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− | </td>
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− | <td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
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− | <div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">Research Report presentation</font></span></div>
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− | </td>
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− | </tr>
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Course Description for BME324, Genomics
by Jong Bhak (jongbhak@gmail.com)
Genomics is the new name for genetics that encompasses not only traditional
genetics research and technology topics but also includes information technology, systems biology, high throughput biodata generation, processing, and analyses.
It covers areas such as sequencing, DNA synthesis, and genome writing and editing.
Genomics course requires the students to have been exposed to general
biology, data processing, statistics, mathematics, and computer science.
The genomic research can be largely divided into experimental and informatic
parts. The course will not cover hands-on experiments due to space limitation.
Students who took this subject will be able to understand life in terms of information processing with much knowledge on how to use technologies to solve problems such as curing cancer and aging.
The topics of genomics include:
1. What is life, information, and the universe? (as information processing objects)
2. What is Omics? (as an approach of understanding life)
3. What is 'Big data' in biology?
4. How molecules and cells propagate in the universe?
5. Genome reading and writing
6. Curing Cancer using genomics (Oncomics)
7. Curing Aging using genomics (Geromics)
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Text
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Category
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Book
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Title
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Author
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Arthur M. Lesk,
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ISBN
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Remarks
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Oxford University Press
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Course Reserves Designation
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References
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The Atom of Evolution. Genomics & Informatics, December 2004, 2(4):167-173.
Genomic profile analysis of diffuse-type gastric cancers
Genome Biology, 2014
Minke whale genome and aquatic adaptation in cetaceans.
Nature Genetics, 2013. (24th Nov 2013)
Tiger genome and comparative analysis with lion and snow leopard genomes.
Nature Communications, 2013. Sep. 17th.
Whole transcriptome analyses of six thoroughbred horses before and after exercise using RNA-Seq
BMC Genomics. 2012 Sep 12;13:473. doi: 10.1186/1471-2164-13-473.
Grading
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Research report writing and presentation (100%)
Each week, before, class, students are asked to submit research reports on genomics topics.
The final grade will be given by the quality of research reports and presentations (in English)
The important points of grading are:
1. Being scientific in reasoning and presenting
2. Critical thinking level
3. Being independent in thinking
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