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<h1>Korean Genome Project &amp; KOREF</h1>
<h2>Before class</h2>
<h3>SNP</h3>
<p>single nucleotide polymorphism</p>
<p>DNA sequence variation within a population(1%) in which a single nucleotide in the genome.</p>
<h3>Korean Genome Project</h3>
<p>Korean genome project make goal that finds korean-only SNPs. Through this project(KPGP), 60000 SNPs were found as Korean unique SNP.</p>
<p>Most Koreans have mutation about protein associated with capsaicin, the spicy component in chili peppers, which feature heavily in Korean cuisine.</p>
<h3>Difference between reference genome and re-sequenced genome</h3>
<h4>reference genome</h4>
<p>Reference genome is&nbsp;&nbsp;the original model for representing the genome assemblies.</p>
<p>Reference genome is a digital nucleic acid sequence database, assembled by scientists as a representative example of a species' set of genes. Although reference genome don't accurately represent the set of genes of any single person,&nbsp; it provides a haploid mosaic of different DNA sequences from each donor.</p>
<h4>Re-sequenced genome</h4>
<p>When a reference genome already exist in their own species, resequenicng allows investigation of the relationship between sequence variation and normal or disease phenotypes.</p>
<h3>&nbsp;What is KOREF?</h3>
<p>KOREF means korean reference genome.</p>
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