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Interaction proteomics => protein -protein association<br />
Protein family - protein mother, father</p>
<p> </p>
<p>The first person who identify the sequence of amino acid in protein. - Sanger(insulin)</p>
<p> </p>
<p>Pfam - the data base of protein family<br />
interproscan<br />
NCBI NR(non-redundant) db ->largest data base -> check the redundancy</p>
<p> </p>
<p>The level of any protein in the cell of <br />
3. the rate of degradation into half life of mRNA</p>
<p> </p> <p><strong>In my opinion, the number of possilble kinds of protein is 20^300(The number of type of amino acid is 20, and the average length of protein is 300aa ->20*20*20*......*20 ) -> protein space</strong></p> <p> </p>
<p>The number of protein types -> about 100,000 <br />
The number of type of protein structure -> 4000~1000</p>
<p> </p>
<p>secondary structure - alpha helix/ beta sheet</p>
End point of polypeptide - C -terminus</p>
<p>domain - area/region of protein<br /p> <p>determining protein structure<br />
1. X-ray crystallography<br />
2. NMR -> sensor using magnetic radiation<br />