MCM4

From Biolecture.org


  <DNA>

ATGTCGTCCCCGGCGTCGACCCCGAGCCGCCGCGGCAGCCGGCGTGGAAGGGCCACCCCCGCCCAGACGCCTCGGAGTGAGGATGCCAGGTCATCTCCCTCTCAG

AGACGTAGAGGCGAGGATTCCACCTCCACGGGGGAGTTGCAGCCGATGCCAACCTCGCCTGGAGTGGACCTGCAGAGCCCTGCTGCGCAGGACGTGCTGTTTTCCA

GCCCTCCCCAAATGCATTCTTCAGCTATCCCTCTTGACTTTGATGTTAGTTCACCACTGACATACGGCACTCCCAGCTCTCGGGTAGAGGGAACCCCAAGAAGTGGTGT

TAGGGGCACACCTGTGAGACAGAGGCCTGACCTGGGCTCTGCACAGAAGGGCCTGCAAGTGGATCTGCAGTCTGACGGGGCAGCAGCAGAAGATATAGTGGCAAG

TGAGCAGTCTCTAGGCCAAAAACTTGTGATCTGGGGAACAGATGTAAATGTGGCAGCATGCAAAGAAAACTTTCAGAGATTTCTTCAGCGTTTTATTGACCCTCTGGCT

AAAGAAGAAGAAAATGTTGGCATAGATATTACTGAACCTCTATACATGCAACGACTTGGGGAGATTAATGTTATTGGTGAGCCATTTTTAAATGTGAACTGTGAACACAT

CAAATCATTTGACAAAAATTTGTACAGACAACTCATCTCTTACCCACAGGAAGTTATTCCAACTTTTGACATGGCTGTCAATGAAATCTTCTTTGACCGTTACCCTGACTC

AATCTTAGAACATCAGATTCAAGTAAGACCATTCAACGCATTGAAGACTAAGAATATGAGAAACCTGAATCCAGAAGACATTGACCAGCTCATCACCATCAGCGGCAT

GGTGATCAGGACATCCCAGCTGATTCCCGAGATGCAGGAGGCCTTCTTCCAGTGCCAAGTGTGTGCCCACACGACCCGGGTGGAGATGGACCGCGGCCGCATTGCA

GAGCCCAGTGTGTGCGGGCGCTGCCACACCACCCACAGCATGGCACTCATCCACAACCGCTCCCTCTTCTCTGACAAGCAGATGATCAAGCTTCAGGAGTCTCCGGA

AGACATGCCTGCAGGGCAGACACCACACACAGTTATCCTGTTTGCTCACAATGATCTCGTTGACAAGGTCCAGCCTGGGGACAGAGTGAATGTTACAGGCATCTATCG

AGCTGTGCCTATTCGAGTCAATCCAAGAGTGAGTAATGTGAAGTCTGTCTACAAAACCCACATTGATGTCATTCATTATCGGAAAACGGATGCAAAACGTCTGCATGGC

CTTGATGAAGAAGCAGAACAGAAACTTTTTTCAGAGAAACGTGTGGAATTGCTTAAGGAACTTTCCAGGAAACCAGACATTTATGAGAGGCTTGCTTCAGCCTTGGCTC

CAAGCATTTATGAACATGAAGATATAAAGAAGGGAATTTTGCTTCAGCTCTTTGGCGGGACAAGGAAGGATTTTAGTCACACTGGAAGGGGCAAATTTCGGGCTGAGA

TCAACATCTTGCTGTGTGGCGACCCTGGTACCAGCAAGTCCCAGCTGCTGCAGTACGTGTACAACCTCGTCCCCAGGGGCCAGTACACGTCTGGGAAGGGCTCCAGT

GCAGTTGGCCTCACTGCGTACGTAATGAAAGACCCTGAGACAAGGCAGCTGGTCCTGCAGACAGGTGCTCTTGTCCTGAGTGACAACGGCATCTGCTGTATCGATGAG

TTCGACAAGATGAATGAAAGTACAAGATCGGTATTGCATGAAGTCATGGAACAGCAGACTCTGTCCATTGCAAAGGCTGGGATCATCTGTCAGCTCAATGCGCGCACC

TCTGTCCTGGCAGCAGCAAATCCCATTGAGTCTCAGTGGAATCCTAAAAAAACAACCATTGAAAACATCCAGCTGCCTCATACTTTATTATCAAGGTTTGATTTGATCTTC

CTCTTGCTGGACCCTCAGGACGAAGCCTATGACAGGCGTCTGGCTCACCACCTGGTCGCACTGTACTACCAGAGCGAGGAGCAGGCAGAGGAGGAGCTCCTGGACA

TGGCGGTGCTAAAGGACTACATTGCCTACGCGCACAGCACCATCATGCCGCGGCTAAGTGAGGAAGCCAGCCAGGCTCTCATCGAGGCTTATGTAGACATGAGGAA

GATTGGCAGTAGCCGGGGAATGGTTTCTGCATACCCTCGACAGCTAGAGTCATTAATCCGCTTAGCAGAAGCCCATGCTAAAGTAAGATTGTCTAACAAAGTTGAAGC

CATTGATGTGGAAGAGGCCAAACGCCTCCATCGGGAAGCTCTGAAGCAGTCTGCAACTGATCCCCGGACTGGCATCGTGGACATATCTATTCTTACTACGGGGATGAG

TGCCACCTCTCGTAAACGGAAAGAAGAATTAGCTGAAGCATTGAAAAAGCTTATTTTATCTAAGGGCAAAACACCAGCTCTAAAATACCAGCAACTTTTTGAAGATATTC

GGGGACAATCTGACATAGCAATTACTAAAGATATGTTTGAAGAAGCACTGCGTGCCCTGGCAGATGATGATTTCCTGACAGTGACTGGGAAGACCGTGCGCTTGCTCTGA

 

 

  <Protein>

MSSPASTPSRRGSRRGRATPAQTPRSEDARSSPSQRRRGEDSTSTGELQPMPTSPGVDLQSPAAQDVLFSSPPQMHSSAIPLDFDVSSPLTYGTPSSRVEGTPRSGVRGTPVR

QRPDLGSAQKGLQVDLQSDGAAAEDIVASEQSLGQKLVIWGTDVNVAACKENFQRFLQRFIDPLAKEEENVGIDITEPLYMQRLGEINVIGEPFLNVNCEHIKSFDKNLYRQLIS

YPQEVIPTFDMAVNEIFFDRYPDSILEHQIQVRPFNALKTKNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVEMDRGRIAEPSVCGRCHTTHSMALIHNR

SLFSDKQMIKLQESPEDMPAGQTPHTVILFAHNDLVDKVQPGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIHYRKTDAKRLHGLDEEAEQKLFSEKRVELLKELSRKPDIY

ERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDE

FDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHLVALYYQSEEQAEEELLDMAVLKDYIA

YAHSTIMPRLSEEASQALIEAYVDMRKIGSSRGMVSAYPRQLESLIRLAEAHAKVRLSNKVEAIDVEEAKRLHREALKQSATDPRTGIVDISILTTGMSATSRKRKEELAEALKKLILS

KGKTPALKYQQLFEDIRGQSDIAITKDMFEEALRALADDDFLTVTGKTVRLL*

 

 

  <Structure>

http://www.compbio.dundee.ac.uk/jpred4/results/jp_i2d6unP/jp_i2d6unP.simple.html

http://www.compbio.dundee.ac.uk/jpred4/results/jp_F2h0dtL/jp_F2h0dtL.simple.html

 

H: Alpha helix, E: Beta sheet
---------------------------------------------------------------------------------------------------------------------------


HHHHHHHHHHHHHHH-----------------HHHHHHHHHHHH----EEEEEHHHHHH--HHHHHHHHH--HHHHHHHHHHHHHHHHH


EEEEEE-------------------EEEEEEEEEE----HHHHEEEEEEE----EEEEEEE--------------------EE-----EEE-EEEEEEE-------------EEEE

EEE-----EE----EEEEEEEEEEE--------------EEEEEEEEEEEE-----------HHHHH---HHHHHHHHHHHH------------------HHHHHHHHHHHHH--------------


HHHHHHHHHHHH-----EEE----------EEEEE-----HEEEE-----------EEE----------HHHHH------EEEEE---EEEE------EEE-----------


EEEEE-----HHHHHHHHHHHHHHHH------------HHHHHHHHHHHHH----E--HHHHHHHHHHHHHHHH----------HHHHHHHHHHHHHHHHHH-----

-HHHHHHHHHHHHHHHHHHHH--------------------HHHHHHHHHHHHHHHHHH--------HHHHHHHHHHHH-----HHHHHHHHHHHHH--EEEEE---EEEE