Cancer genome

From Biolecture.org

The cancer genome
Michael R. Stratton1,2, Peter J. Campbell1,3 & P. Andrew Futreal1


All cancers arise as a result of changes that have occurred in the DNA sequence of the genomes of cancer cells. Over the past
quarter of a century much has been learnt about these mutations and the abnormal genes that operate in human cancers.We
are now, however, moving into an era in which it will be possible to obtain the complete DNA sequence of large numbers of
cancer genomes. These studies will provide us with a detailed and comprehensive perspective on how individual cancers
have developed.