Difference between revisions of "Essay"

From Biolecture.org
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<p style="text-align: center;"><strong>What is Genomics</strong></p>
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<p style="text-align: center;"><strong>About Omics</strong></p>
  
 
<p><strong>1. Abstract</strong></p>
 
<p><strong>1. Abstract</strong></p>
  
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<p>Genomics research genetic information which is total genes of certain life. Genomics have 5 objectives and 4 representative research directions. Also there are several accomplishments which genomics helped to people.</p>
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<p>Omics is study which research body, so it include many various fields. So in this essay, there are 12 kinds of fields. However there are much more fields in detail. Let&rsquo;s see what kinds of fields are in omics and why they divided.</p>
  
 
<p>&nbsp;</p>
 
<p>&nbsp;</p>
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<p><strong>2. Intro</strong></p>
 
<p><strong>2. Intro</strong></p>
  
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<p>&lt;Objective of Genomics&gt;</p>
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<p>The suffix &lsquo;-ome&rsquo; means &#39;body&#39;, which means all of a collection of molecules or cells in modern life science. In omics, bioinformatics techniques are used to break away from existing fragmentary research and attempt a comprehensive and holistic paradigm to collectively study large amounts of biological information and their interrelationships.</p>
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<ul>
 
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<li>Identify the gene identification of 80,000 human genes.</li>
 
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<li>Determine the 3 billion chemical base sequences that make up the human DNA.</li>
 
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<li>Record database information.</li>
 
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<li>Develop and complement the technical problems of data analysis.</li>
 
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<li>Explain about the moral, legal, and social issues related to the project.</li>
 
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</ul>
 
  
 
<p>&nbsp;</p>
 
<p>&nbsp;</p>
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<p><strong>3. Result</strong></p>
 
<p><strong>3. Result</strong></p>
  
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<p>Genome is genetic information, also total genes in nucleus. It is also the set of genes and on unit required for maintenance of life phenomena and for the expression of all traits.</p>
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<p>&lt;Fields of Omics&gt;</p>
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<ol>
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<li>Genomics</li>
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</ol>
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<p style="margin-left:40.0pt">Field of study of genes. Also Field of bioinformatics such as proteomics, transcription physiology, interactive biology.</p>
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<ol>
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<li>Transcriptomics</li>
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</ol>
  
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<p>Substances containing information are DNA and RNA. DNA is consist of various combination of Adenine(A), Guanine(G), Cytosine(C) and Thymine(T) while RNA is consist of various combination of &nbsp;Adenine(A), Guanine(G), Cytosine(C) and Uracil(U). Understanding the sequence of these bases can reveal the unique nucleotide sequence of each organism.</p>
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<p style="margin-left:40.0pt">Field of study the totality of expressed RNAs.</p>
  
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<p>Genomics reveals the structure and function of all genomes in living organisms. It includes mainly gene mapping, production and analysis of mutant animals, causative gene nomenclature related to disease genes and special traits, and development of molecular markers.</p>
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<p style="margin-left:40.0pt">With the sum of expressed proteins, expressome is formed. The research that combines these two is called Expressomics.</p>
  
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<p>&nbsp;</p>
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<ol>
 +
<li>Proteomics</li>
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</ol>
 +
 
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<p style="margin-left:40.0pt">Field of study all proteins in cells or in individuals.</p>
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<p style="margin-left:40.0pt">Ultimately, the basic unit of human bioactivity is protein. There are many varieties of proteins with many variations, and every possible protein set for a functional unit is called a proteome.</p>
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<ol>
 +
<li>Lipidomics</li>
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</ol>
  
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<p>&lt;Direction of Genomics&gt;</p>
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<p style="margin-left:40.0pt">Field of study pathway and networks of lipids.</p>
  
 
<ol>
 
<ol>
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<li>Functional genomics:</li>
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<li>Foodomics</li>
 
</ol>
 
</ol>
  
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<p style="margin-left:40.0pt">Field of study the function of genes and gene products.</p>
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<p style="margin-left:40.0pt">Field of study the food and nutrition domains through the application.</p>
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<ol>
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<li>Interactomics</li>
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</ol>
  
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<p style="margin-left:40.0pt">There are Biological and biochemical approaches to gene function. The biological approach is to observe changes in physiological function by removing specific genes from model animals used in laboratories. This method is mainly used to find out which gene is the cause of the disease. The biochemical approach is to track what proteins are made from known genetic information and to reveal their structure and function.</p>
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<p style="margin-left:40.0pt">Field of study the totality of the interactions of molecules within a cell and of protein interactions.</p>
  
 
<ol>
 
<ol>
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<li>Comparative genomics</li>
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<li>Metabolomics</li>
 
</ol>
 
</ol>
  
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<p style="margin-left:40.0pt">Field of study individual differences in race, disease outbreaks, and medicines based on the results of the standard sequence.</p>
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<p style="margin-left:40.0pt">Field of study and analyze metabolites and metabolic circuits in the cell in general.</p>
  
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<p style="margin-left:40.0pt">There are two methods for finding genes related to genetic diseases: functional cloning and positional cloning. Functional cloning is a method of predicting the function of a disease gene and locating a gene. Local cloning is present in the precursor chromosome without information about the disease gene.</p>
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<p style="margin-left:40.0pt">Metabolomics is one of the core branches of genomics. It the expression of all metabolites generated by genotypes and their regulatory results in relation to genomes. Metabolism is mainly based on extracting and analyzing everything that can be classified in blood, and its application is mainly studying metabolic diseases.</p>
  
 
<ol>
 
<ol>
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<li>Personal genomics</li>
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<li>Textomics</li>
 
</ol>
 
</ol>
  
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<p style="margin-left:40.0pt">Field of study individual genomes by interpreting and comparing.</p>
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<p style="margin-left:40.0pt">Field of study biological objects in the literature as organic networks.</p>
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 +
<ol>
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<li>Pharmacogenomics</li>
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</ol>
  
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<p style="margin-left:40.0pt">In order to solve the problems raised in the fields of biology, medicine, industry and the like that systematically study genomes and related information which are the sum of individual genes of specific organisms for solving problems raised in biology, medicine, industry, etc. A systematic study of genome and related information as a whole.</p>
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<p style="margin-left:40.0pt">Field of study the correlation between drugs and genomes of living organisms using sequencing and bioinformatics pharmacology.</p>
  
 
<ol>
 
<ol>
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<li>Late genomics</li>
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<li>Chemical genomics</li>
 
</ol>
 
</ol>
  
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<p style="margin-left:40.0pt">Field of study DNA genome sequence through human genome project and compares genome function and individual nucleotide sequence with others.</p>
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<p style="margin-left:40.0pt">Field of study the expression and function of a large number of genes using a large variety of chemical substances.</p>
  
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<p style="margin-left:40.0pt">It is necessary to clarify the functions of the mapped genome and to compare and analyze characteristics between individuals. Two methods can be used to reveal individual differences. One is study of gene discovery and function by functional genomics, and the other is the comparison genomics, which identifies individual differences in race, disease outbreaks, and drugs based on human standard sequence results.</p>
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<ol>
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<li>Physiomics</li>
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</ol>
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<p style="margin-left:40.0pt">Field of study a large amount of experimental information.</p>
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<ol>
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<li>Geromics</li>
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</ol>
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<p style="margin-left:40.0pt">Field of study systematically discovering, diagnosing, and treating biologic and sociological aging phenomenon systematically using the vocational techniques.</p>
  
 
<p>&nbsp;</p>
 
<p>&nbsp;</p>
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<p><strong>4. Discussion</strong></p>
 
<p><strong>4. Discussion</strong></p>
  
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<p>During searching genomics, I couldn&rsquo;t know what can we do with genomics and how is it used. So I chose the question and searched usage of present.</p>
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<p>While Investigating omics, I realized that there are a lot of fields in omics. This is applies not only to omics but also to other studies.</p>
 +
 
 +
<p>Why did these many fields need to divide?</p>
  
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<p>&lt;Accomplishment of Genomics&gt;</p>
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<p>If there are no enough divided fields, aspects to one certain subject will not be various. It might lead to confusion in the study.</p>
  
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<ul>
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<p>But if there are enough kinds of fields, when researcher in each fields will study one certain subject, the result of research will come much clear and persuasively.</p>
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<li>Found CRISPR by comparing genomes of bacteria.</li>
 
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<li>Created a partially synthetic species of bacterium, Mycoplasma laboratorium, derived from the genome of Mycoplasma genitlium.</li>
 
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<li>Plan to help a given species with many unknown variables by studying their genome.</li>
 
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</ul>
 
  
 
<p>&nbsp;</p>
 
<p>&nbsp;</p>
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<p><strong>5. Reference</strong></p>
 
<p><strong>5. Reference</strong></p>
  
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<p>Wikipedia; Genomics; <a href="https://en.wikipedia.org/wiki/Genomics">https://en.wikipedia.org/wiki/Genomics</a></p>
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<p>Wikipedia; Omics; <a href="https://en.wikipedia.org/wiki/Omics#Lipidomics">https://en.wikipedia.org/wiki/Omics#Lipidomics</a></p>
  
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<p>News Medical; What is Genomics?;&nbsp;<a href="http://www.news-medical.net/life-sciences/What-is-Genomics.aspx">http://www.news-medical.net/life-sciences/What-is-Genomics.aspx</a></p>
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<p>Wikipedia; 체학; <a href="https://ko.wikipedia.org/wiki/%EC%B2%B4%ED%95%99">https://ko.wikipedia.org/wiki/%EC%B2%B4%ED%95%99</a></p>

Latest revision as of 15:52, 5 December 2016

About Omics

1. Abstract

Omics is study which research body, so it include many various fields. So in this essay, there are 12 kinds of fields. However there are much more fields in detail. Let’s see what kinds of fields are in omics and why they divided.

 

2. Intro

The suffix ‘-ome’ means 'body', which means all of a collection of molecules or cells in modern life science. In omics, bioinformatics techniques are used to break away from existing fragmentary research and attempt a comprehensive and holistic paradigm to collectively study large amounts of biological information and their interrelationships.

 

3. Result

<Fields of Omics>

  1. Genomics

Field of study of genes. Also Field of bioinformatics such as proteomics, transcription physiology, interactive biology.

  1. Transcriptomics

Field of study the totality of expressed RNAs.

With the sum of expressed proteins, expressome is formed. The research that combines these two is called Expressomics.

  1. Proteomics

Field of study all proteins in cells or in individuals.

Ultimately, the basic unit of human bioactivity is protein. There are many varieties of proteins with many variations, and every possible protein set for a functional unit is called a proteome.

  1. Lipidomics

Field of study pathway and networks of lipids.

  1. Foodomics

Field of study the food and nutrition domains through the application.

  1. Interactomics

Field of study the totality of the interactions of molecules within a cell and of protein interactions.

  1. Metabolomics

Field of study and analyze metabolites and metabolic circuits in the cell in general.

Metabolomics is one of the core branches of genomics. It the expression of all metabolites generated by genotypes and their regulatory results in relation to genomes. Metabolism is mainly based on extracting and analyzing everything that can be classified in blood, and its application is mainly studying metabolic diseases.

  1. Textomics

Field of study biological objects in the literature as organic networks.

  1. Pharmacogenomics

Field of study the correlation between drugs and genomes of living organisms using sequencing and bioinformatics pharmacology.

  1. Chemical genomics

Field of study the expression and function of a large number of genes using a large variety of chemical substances.

  1. Physiomics

Field of study a large amount of experimental information.

  1. Geromics

Field of study systematically discovering, diagnosing, and treating biologic and sociological aging phenomenon systematically using the vocational techniques.

 

4. Discussion

While Investigating omics, I realized that there are a lot of fields in omics. This is applies not only to omics but also to other studies.

Why did these many fields need to divide?

If there are no enough divided fields, aspects to one certain subject will not be various. It might lead to confusion in the study.

But if there are enough kinds of fields, when researcher in each fields will study one certain subject, the result of research will come much clear and persuasively.

 

5. Reference

Wikipedia; Omics; https://en.wikipedia.org/wiki/Omics#Lipidomics

Wikipedia; 체학; https://ko.wikipedia.org/wiki/%EC%B2%B4%ED%95%99

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