Jihwan Jeon/Assignment

From Biolecture.org

List 30 vocabularies in genomics and explain it with your own words.

 

1. Genomics

Genomics is a field of biology that studies the whole procedure of biological system from DNA to protein expression.

 

2. Sequencing

Sequencing is to read out the lists of bases in DNA

 

3. DNA

DNA is genetic materials that has all information about the organsm.

 

4. RNA

RNA is genetic materials that helps expression process of DNA to protein. It is made of single stranded sequence of nucleotides.

 

5. Nucleotide

Nucleotide is basic unit of DNA sequences that is composed of base, glucose and phospate.

 

6. Base

Base is a chemical group in nucleotide that represent genetic information of DNA sequence

 

7. Genotype

Genotype is expression of specific character based on DNA sequence

 

8. Phenotype

Phenotype is expression of specific character based on its real protein expression.

 

9. Exon

Exon is a part of DNA that has valid information.

 

10. Intron

Intron is a part of DNA that does not have genetic information

 

11. Allel

Allel is a complementary pair in chromosome that has same location in sequence.

 

12. Chromosome

Chromosome is a individual molecule that compose DNA.

 

13. Genome sequencing project

The project to know total sequence of organism.

 

14. Sanger method

The primitive method of DNA sequencing using DNA polymerase.

 

15. Sequence assembly

The technique that assemble short DNA sequnces to get whole DNA sequence

 

16. DNA annotation

The process that finds out the location of specific gene

 

17. Epigenomics

One field of genomics that deals with epigenetic process of genetic materials.

 

18. DNA polymerase

The protein that helps duplication of DNA

 

19. Mutation

The incidental change of genetic sequence.

 

20. 5' and 3' terminal

The representation in DNA sequence to prevent misuniderstanding direction

 

21. Recombinant DNA

DNA that is made manually from RNA sequence

 

22. Protein expression

The formation of specific protein from DNA sequence

 

23. Transcription

The formation of mRNA from DNA

 

24. Translation

The formation of peptide sequence from mRNA.

 

25. tRNA

tRNA is RNA molecules that interact with mRNA and assign specific animo acid during translation.

 

26. Post Translation Modification

The modification of animo acids after translation. i.e. hyroxylation, methylation, phosphorylation

 

27. FASTA

FASTA is a format to express DNA sequence

 

28. BLAST

BLAST is a algorithm for comparing gene sequences

 

29. Bioinformatics

One field of genomics that interpret DNA sequences using computational method

 

30. Allignment

Comparing the sequences based on some specific site.