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Trancriptomics Assay

375 bytes removed, 00:38, 21 May 2015
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<p>&nbsp;</p>
<ol style="list-style-type: decimal; direction: ltr"> <li style="font-size: 12pt; font-weight: normal; color: black; font-style: normal"> <h1h2><span style="font-size: 13.5pt; color: black; sans-serif: ">&nbsp;&nbsp;&nbsp;&nbsp; What is transcriptomics?</span></h1> </li></olh2>
<p style="background: white; margin: 4.8pt 0cm 6pt 20pt; line-height: 14.3pt"><span style="font-size: 13.5pt; color: black; sans-serif: ">Thranscriptomics is discipline of biology that study about the set of all RNA moleculs, including mRNA, rRNA, tRNA and non-coding RNA transcribed in one cell or a population of cells</span></p>
<div p style="background: white; margin: 4.8pt 0cm 6pt 20pt; line-height: 14.3pt">&nbsp;</divp><ol p style="list-style-typebackground: decimalwhite; directionmargin: ltr"> <li style="font-size: 12pt4.8pt 0cm 6pt 20pt; fontline-weightheight: normal14.3pt">&nbsp; color: black; font-style: normal"</p> <h1h2><span style="font-size: 13.5pt; color: black; sans-serif: ">Relationship between genomics and transcriptomics</span></h1h2> </lip style="background: white; margin: 4.8pt 0cm 6pt 20pt; line-height: 14.3pt">&nbsp;</olp>
<p style="background: white; margin: 4.8pt 0cm 6pt 20pt; line-height: 14.3pt"><span style="font-size: 13.5pt; color: black; sans-serif: ">Transcriptomics is expressional genomics. </span></p>
<div p style="background: white; margin: 4.8pt 0cm 6pt 38pt20pt; line-height: 14.3pt">&nbsp;</divp><ol p style="list-style-typebackground: decimalwhite; directionmargin: ltr"> <li style="font-size: 12pt4.8pt 0cm 6pt 20pt; fontline-weightheight: normal14.3pt">&nbsp; color: black; font-style: normal"</p> <h1h2><span style="font-size: 13.5pt; color: black; sans-serif: ">What are mRNAs?</span></h1h2> </lip style="background: white; margin: 4.8pt 0cm 6pt 20pt; line-height: 14.3pt">&nbsp;</olp>
<p style="background: white; margin: 4.8pt 0cm 6pt 20pt; line-height: 14.3pt"><span style="font-size: 13.5pt; color: black; sans-serif: ">mRNA is large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence if the protein products of gene expressing</span></p>
<div p style="background: white; margin: 4.8pt 0cm 0cm 8pt 40pt6pt 20pt; line-height: 14.3pt">&nbsp;</divp><div p style="background: white; margin: 4.8pt 0cm 6pt 38pt20pt; line-height: 14.3pt">&nbsp;</div><ol style="list-style-type: decimal; direction: ltr"> <li style="font-size: 12pt; font-weight: normal; color: black; font-style: normal"p> <h1h2><span style="font-size: 13.5pt; color: black; sans-serif: ">How to measure RNA expression?</span></h1> </li></olh2><p style="background: white; margin: 4.8pt 0cm 6pt 38pt20pt; line-height: 14.3pt"><span style="font-size: 13.5pt; sans-serif: ">RNA-seq method is frequently used for measuring RNA expression.</span></p><div p style="background: white; margin: 4.8pt 0cm 6pt 38pt20pt; line-height: 14.3pt">&nbsp;</divp><div p style="background: white; margin: 4.8pt 0cm 6pt 38pt20pt; line-height: 14.3pt">&nbsp;</div><ol style="list-style-type: decimal; direction: ltr"> <li style="font-size: 12pt; font-weight: normal; color: black; font-style: normal"p> <h1h2><span style="font-size: 13.5pt; color: black; sans-serif: ">Relationship between Transcriptome and Proteome.</span></h1> </li></olh2>
<div style="background: white; margin: 4.8pt 0cm 6pt; line-height: 14.3pt; text-indent: 20.25pt"><span style="font-size: 13.5pt; color: black; sans-serif: ">Proteome is expressional Transcriptome. </span></div>
<div style="background: white; margin: 4.8pt 0cm 0cm 8pt 40pt6pt; line-height: 14.3pt; text-indent: 20.25pt">&nbsp;</div><div style="background: white; margin: 4.8pt 0cm 6pt 38pt; line-height: 14.3pt; text-indent: 20.25pt">&nbsp;</div><ol style="list-style-type: decimal; direction: ltr"> <li style="font-size: 12pt; font-weight: normal; color: black; font-style: normal"> <h1h2><span style="font-size: 13.5pt; color: black; sans-serif: ">What is a UTR?</span></h1h2> </lidiv style="background: white; margin: 4.8pt 0cm 6pt; line-height: 14.3pt; text-indent: 20.25pt">&nbsp;</oldiv>
<p style="background: white; margin: 4.8pt 0cm 6pt 20pt; line-height: 14.3pt"><span style="font-size: 13.5pt; background: white; sans-serif: ">Untranslated region </span><span style="font-size: 13.5pt; background: white; sans-serif: ">(or&nbsp;UTR) refers to either of two sections, one on each side of a&nbsp;</span><a title="Coding sequence" href="http://en.wikipedia.org/wiki/Coding_sequence"><span style="font-size: 13.5pt; text-decoration: none; background: white; color: windowtext; text-underline: none; sans-serif: ">coding sequence</span>&nbsp;<span style="font-size: 13.5pt; background: white; sans-serif: ">on a strand of&nbsp;</span></a><a title="MRNA" href="http://en.wikipedia.org/wiki/MRNA"><span style="font-size: 13.5pt; text-decoration: none; background: white; color: windowtext; text-underline: none; sans-serif: ">mRNA</span><span style="font-size: 13.5pt; background: white; sans-serif: ">. If it is found on the 5' side, it is called the&nbsp;</span></a><a title="Five prime untranslated region" href="http://en.wikipedia.org/wiki/Five_prime_untranslated_region"><span style="font-size: 13.5pt; text-decoration: none; background: white; color: windowtext; text-underline: none; sans-serif: ">5' UTR</span>&nbsp;<span style="font-size: 13.5pt; background: white; sans-serif: ">(or&nbsp;leader sequence), or if it is found on the 3' side, it is called the&nbsp;</span></a><a title="Three prime untranslated region" href="http://en.wikipedia.org/wiki/Three_prime_untranslated_region"><span style="font-size: 13.5pt; text-decoration: none; background: white; color: windowtext; text-underline: none; sans-serif: ">3' UTR</span>&nbsp;<span style="font-size: 13.5pt; background: white; sans-serif: ">(or&nbsp;trailer sequence).</span></a></p>
<div p style="background: white; margin: 4.8pt 0cm 6pt 38pt20pt; line-height: 14.3pt">&nbsp;</divp><ol p style="list-style-typebackground: decimalwhite; directionmargin: ltr"> <li style="font-size: 12pt4.8pt 0cm 6pt 20pt; fontline-weightheight: normal14.3pt">&nbsp; color: black; font-style: normal"</p> <h1h2><span style="font-size: 13.5pt; color: black; sans-serif: ">What is ncRNA&nbsp;?</span></h1h2> </lip style="background: white; margin: 4.8pt 0cm 6pt 20pt; line-height: 14.3pt">&nbsp;</olp>
<div style="margin: 0cm 0cm 8pt 15pt"><span style="font-size: 13.5pt; background: white; line-height: 107%; sans-serif: ">A&nbsp;non-coding RNA&nbsp;(ncRNA) is a functional&nbsp;</span><a title="RNA" href="http://en.wikipedia.org/wiki/RNA"><span style="font-size: 13.5pt; text-decoration: none; background: white; color: windowtext; line-height: 107%; text-underline: none; sans-serif: ">RNA</span>&nbsp;<span style="font-size: 13.5pt; background: white; line-height: 107%; sans-serif: ">molecule that is not&nbsp;</span></a><a title="Translation (genetics)" href="http://en.wikipedia.org/wiki/Translation_(genetics)"><span style="font-size: 13.5pt; text-decoration: none; background: white; color: windowtext; line-height: 107%; text-underline: none; sans-serif: ">translated</span><span style="font-size: 13.5pt; background: white; line-height: 107%; sans-serif: "> into a&nbsp;</span></a><a title="Protein" href="http://en.wikipedia.org/wiki/Protein"><span style="font-size: 13.5pt; text-decoration: none; background: white; color: windowtext; line-height: 107%; text-underline: none; sans-serif: ">protein</span></a></div>
<div style="background: white; margin: 4.8pt 0cm 6pt 38pt; line-height: 14.3pt">&nbsp;</div>
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