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GiJeong Kim

1,034 bytes added, 22:07, 10 June 2015
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<p><b>PROTEOMICS</b></p>
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<li>What is proteome?proteome is the total set of proteins expressed as the product of genes.</li> <li>Relationship between genomics, transcriptomics, and proteomics.Proteome is the most highly related phenotype of the cell, or organism. In determining the phenotype, some proteins are upregulated and some downregulated or some is undergone modification. genomics and transcriptomics provide the basis of such control mechanism. They're related in terms of sequence. Although polypeptide sequence consists of amino acids, amino acids are designated by codon.&nbsp;</li>
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<p>&nbsp;-in the class</p>
<ul>
<li>How many proteins in the cell?</li>
<li>a-helix is right-handed helix. what determines handness? 20 amino acids that makes up proteins are all L-forms(glycine is achiral), favoring right handed helix. Even more, of around 500 natural exsisting amino acids, only 8 amino acids are D-form. there is argument by Mason that electroweak force of fundamental particles - fermions(quarks, leptons, etc.) - involves such imbalance of L- and D- form amino acid[9].</li>
<li>discussion of Foldit - by SoonGu Kim</li>
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