Changes
From Biolecture.org
no edit summary
<p style="text-align: center;"><span style="font-size:36px"><Index of Chapter 1></span></p>
<p><span class="marker"><span style="font-size:14px"><span style="font-family:comic sans ms,cursive"><span style="color:#0000CD"><strong><samp>The human genome</samp></strong></span></span></span></span></p>
<p><span style="font-size:14px"><span style="font-family:comic sans ms,cursive"><samp>Phenotype = Genotype +Environment + Life history + Epigenetics</samp></span></span></p>
<p> </p>
<p><span class="marker"><span style="font-size:14px"><span style="font-family:comic sans ms,cursive"><span style="color:#0000CD"><strong><samp>Contents of the human genome</samp></strong></span></span></span></span></p>
<p>Francis Crick encapsulated this scheme in the Central Dogma of Molecular biology. </p>
<p> </p>
<p><span class="marker"><span style="font-size:14px"><span style="font-family:comic sans ms,cursive"><span style="color:#0000CD"><strong><samp>Genes that encode the proteome</samp></strong></span></span></span></span></p>
<p>Proteome- that is the amino acid sequences of the proteins expressed. However, several mechanisms introduce additional variety into the genome - protemeome relationship.</p>
<p> </p>
<p><span class="marker"><span style="font-size:14px"><span style="font-family:comic sans ms,cursive"><span style="color:#0000CD"><strong><samp>Varieties of genome organization</samp></strong></span></span></span></span></p>
<p>Chromosomes. organlleles, and plasmids. </p>
<p> </p>
<p><span class="marker"><span style="font-size:14px"><span style="font-family:comic sans ms,cursive"><span style="color:#0000CD"><strong><samp>Genome sequencing projects</samp></strong></span></span></span></span></p>
<p><span class="marker"><span style="font-size:14px"><span style="font-family:comic sans ms,cursive"><span style="color:#0000CD"><strong><samp>Variations within and between populations</samp></strong></span></span></span></span></p>
<p><span class="marker"><span style="font-size:14px"><span style="font-family:comic sans ms,cursive"><span style="color:#0000CD"><strong><samp>Human genome sequencing</samp></strong></span></span></span></span></p>
<p><span class="marker"><span style="font-size:14px"><span style="font-family:comic sans ms,cursive"><span style="color:#0000CD"><strong><samp>The human genome and medicine</samp></strong></span></span></span></span></p>
<p><span class="marker"><span style="font-size:14px"><span style="font-family:comic sans ms,cursive"><span style="color:#0000CD"><strong><samp>The evolution and development of databases</samp></strong></span></span></span></span></p>
<p><span class="marker"><span style="font-size:14px"><span style="font-family:comic sans ms,cursive"><span style="color:#0000CD"><strong><samp>Protein evolution : Divergence of sequences and structures within and between species</samp></strong></span></span></span></span></p>
<p><span class="marker"><span style="font-size:14px"><span style="font-family:comic sans ms,cursive"><span style="color:#0000CD"><strong><samp>Ethical, lega and social issues</samp></strong></span></span></span></span></p>
<p> </p>
