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From Biolecture.org
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<p>More than 50 kinds of histone modifications have been known.</p>
<p>Most well known example is histone acetylation</p>
<p>Histone acetylation is the process that lysine resides from the histone core of the nucleosome are acetylated by histone acetyltransferase</p>
<p>Scientists encounter a problem that which kind of combination is used for gene activation or gene inactivation.</p>
<h2>Why is it important ? >>> Epigenetic modifications regulate gene activity and expression during development and differentiation, or in response to environmental stimuli</h2>