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Sung Hu

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<p><span style="font-size: small">&nbsp;&nbsp;&nbsp; [http://www.onemedicine.tuskegee.edu/Bioinformatics/rcmi/Bioprogramming.htm]</span></p>
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<li><span style="font-size: medium">[[What is real?]]</span>
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<p><b><span style="font-size: 24pt">Genomics</span></b></p>
<div style="text-align: left; margin: 0cm 0cm 8pt; line-height: normal; -ms-word-break: keep-all" align="left"><span style="font-size: 13.5pt">8) What is poly A&nbsp;?</span></div>
<p style="text-align: left; margin: 0cm 0cm 8pt; line-height: normal; -ms-word-break: keep-all" align="left"><span style="font-size: 13.5pt">-A poly A tail is added to an RNA at the end of transcription. On mRNAs, the poly A tail protects the mRNA molecule from enzymatic degradation in the cytoplasm and aids in transcription termination, export of the mRNA from the nucleus, and translation.</span></p>
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<div style="margin: 0.67em 0cm"><b><font size="6">Proteomics</font></b></div>
<p><span><font size="+0">2. Relationship between genomics, transcriptomics, and proteomics.</font></span></p>
<p style="text-align: left; margin: 0cm 0cm 8pt; line-height: normal; -ms-word-break: keep-all" align="left"><span style="font-size: 12pt">It is related to central dogma. DNAs are transcripted to RNAs, and the RNAs are translated to proteins. Genomics are study about every gene, DNA and RNA. And transcriptiomics are study about expression RNA from DNA. Also proteomics is study about every protein from RNA. Therefore, three study have close relation. </span></p>
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<div style="text-align: left; margin: 0cm 0cm 8pt; line-height: normal; -ms-word-break: keep-all" align="left"><span style="font-size: large"><b><span style="color: black">Epigenomic</span></b></span></div><p style="text-align: left; margin: 0cm 0cm 8pt; line-height: normal; -ms-word-break: keep-all" align="left"><span style="font-size: 13.5pt; color: black"><font size="+0">-the study of the complete set of <b>epigenetic modifications </b>on the genetic material of a cell, known as the epigenome. </font></span></p><div style="text-align: left; margin: 0cm 0cm 8pt; line-height: normal; -ms-word-break: keep-all" align="left"><span style="font-size: 13.5pt; color: black"><a href="http://en.wikipedia.org/wiki/Epigenomics"><font color="#0000ff">http://en.wikipedia.org/wiki/Epigenomics</font></a></span></div><div style="text-align: left; margin: 0cm 0cm 8pt; line-height: normal; -ms-word-break: keep-all" align="left"><span style="font-size: 13.5pt; color: black">-DNA methylation</span></div><p><span style="font-size: 13.5pt; color: black; line-height: 107%">-&gt; methylation of DNA strands can serve to distinguish parent strands from newly synthesized strands, a function that is critical to mismatch repair.</span></p><div style="text-align: left; margin: 0cm 0cm 8pt; line-height: normal; -ms-word-break: keep-all" align="left">&nbsp;</pdiv>
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