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Frna

21 bytes added, 17:46, 29 May 2011
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<p>fRNA</p>
<p>Functional RNA.</p>
<p>A functional<b>non-coding RNA</b><span style="color: #000000"> (f<b>ncRNARNA</b>) is a functional non-coding RNA molecule that is not translated into a protein. </span></p><p><span style="color: #000000">Less-frequently used synonyms are non-protein-coding RNA (npcRNA), non-messenger RNA (nmRNA), and small non-messenger RNA (snmRNA) and functional RNA (fRNA). The term <b>small RNA</b> (<b>sRNA</b>) is often used for small bacterial ncRNAs. The DNA sequence from which a non-coding RNA is transcribed as the end product is often called an <b>RNA gene</b> or non-coding RNA gene.</span></p>
<p><span style="color: #000000">Non-coding RNA genes include highly abundant and functionally important RNAs such as transfer RNA (tRNA) and ribosomal RNA (rRNA), as well as RNAs such as snoRNAs, microRNAs, siRNAs and piRNAs and the long ncRNAs that include examples such as Xist and HOTAIR (see here for a more complete list of ncRNAs). The number of ncRNAs encoded within the human genome is unknown, however recent transcriptomic and bioinformatic studies suggest the existence of thousands of ncRNAs.<sup id="cite_ref-pmid15790807_0-0" class="reference"><font size="2">[1]</font></sup><sup id="cite_ref-pmid17571346_1-0" class="reference"><font size="2">[2]</font></sup><sup id="cite_ref-pmid17568003_2-0" class="reference"><font size="2">[3]</font></sup><sup><font size="2">, but see</font></sup> <sup id="cite_ref-3" class="reference"><font size="2">[4]</font></sup> Since many of the newly identified ncRNAs have not been validated for their function, it is possible that many are non-functional.<sup id="cite_ref-pmid15851066_4-0" class="reference"><font size="2">[5]</font></sup></span></p>
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