Changes

 Cancer has traditionally been understood as a disease caused by genetic mutations. <br/> However, through this course, I have come to realize that epigenetics also plays a crucial role in the development of cancer.&nbsp;<br/> <br/> Epigenetics involves the regulation of gene expression without changes in the DNA sequence itself. <br/> It is noteworthy that gene expression can be regulated through mechanisms <br/> such as DNA methylation, histone modification, and chromatin remodeling. Changes in gene expression patterns can lead to the development of cancer cells.<br/> <br/> Understanding that there are causes of cancer beyond genetic mutations is important. <br/> If we consider only genetic mutations as the cause of cancer, treatments would focus solely on analyzing DNA sequences. <br/> However, if the cause lies in epigenetics, simply examining DNA sequences would not suffice to uncover <br/> the reasons for the cancer. Knowing that epigenetics can also be a cause of cancer broadens the horizons of cancer treatment, enabling more diverse approaches for treating patients.<br/> <br/> Numerous studies have been conducted to demonstrate how epigenetics can explain cancer. Among them, research <br/> on the epigenetic regulatory factor known as the Polycomb group protein has been significant. <br/> Polycomb proteins play a role in repressing genes during development. Abnormalities in these proteins can disrupt gene expression <br/> and completely alter the future of cells.<br/> <br/> So, how should our approach to treatment expand in the future?<br/> Firstly, both genetic and epigenetic factors should be considered in cancer diagnosis. <br/> This could allow for the detection of early signs of cancer that have not been discovered previously, enabling prompt action.&nbsp;<br/> <br/> Additionally, we could consider methods such as artificially introducing proteins that regulate genes, <br/> similar to how hormone injections are administered when there is a deficiency. Using proteins to properly <br/> regulate gene expression could potentially prevent cells from developing into cancer cells.&nbsp;<br/> <br/> By embracing a broader understanding of the genetic and epigenetic factors involved in cancer, <br/> we open up new possibilities for early detection, prevention, and more personalized treatments, enhancing <br/> the efficacy of our approaches against this complex disease.