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Ilsun Yun/Homework1

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<li>hierarchal shotgun sequencing-a genome sequencing strategy in which small DNA fragments are mapped prior to DNA sequencing.</li>
<li>whole genome shotgun sequencing-a genome sequencing strategy in which the entire genome is isolated and sheared into small and large fragments and cloned into vectors.</li>
<li>Human Genome Project-a 13-year effort with US department of health to find:<br />
1.a genetic linkage map of the human genome<br />
2.a physical map of the human genome<br />
3.the DNA sequence of the entire human genome<br />
4.technology for management of the human genome<br />
5.analyze the genomes of other model organisms<br />
6.develop programs focused on on ethical, legal, and social implications of results from human genome project.</li>
<li>pyrosequencing-Genomic DNA is broken into small 300 to 800bp fragments which are attached to beads via adaptors and emulsified in an oil/water mixture and isolated into droplets, which are amplified into many identical products.</li>
<li>comparative genomics-the study of differences of genomic variation between different populations</li>
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