Changes

<pul> <li>Active Site :&nbsp;The specific portion of an enzyme that attaches to the substrate by means of weak chemical bonds.</pli> <li>Alignment :&nbsp;arranging the sequences of DNA, RNA, or protein to identify similarities</li></ul>

<pul> <li>Bioinformatics&nbsp;:&nbsp;an&nbsp;interdisciplinary&nbsp;field that develops methods and&nbsp;software tools&nbsp;for understanding&nbsp;biological&nbsp;data. As an&nbsp;interdisciplinary&nbsp;field of science, bioinformatics combines&nbsp;Computer Science,&nbsp;Biology,&nbsp;Mathematics, and&nbsp;Engineering&nbsp;to analyze and interpret biological data.</pli></ul>

<hr /ul> <pli>BLAST :&nbsp;Basic&nbsp;Local&nbsp;Alignment&nbsp;Search&nbsp;Tool is an&nbsp;algorithm&nbsp;for comparing&nbsp;primary&nbsp;biological sequence information, such as the&nbsp;amino-acid&nbsp;sequences of&nbsp;proteins&nbsp;or the&nbsp;nucleotides&nbsp;of&nbsp;DNA sequences.</pli> <li>Biomarker :&nbsp;generally refers to a measurable&nbsp;indicator&nbsp;of some biological state or condition. The term is also occasionally used to refer to a substance whose detection indicates the presence of a&nbsp;living organism.</li></ul>

<pul> <li>Central dogma :&nbsp;The&nbsp;<strong>central dogma of molecular biology</strong>&nbsp;is an explanation of the flow of genetic information within a biological system.</pli></ul>

<p>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; DNA(Duplication)&nbsp;&rarr; RNA&nbsp;&rarr; Protein</p>

<pul> <li>Protein Domain :&nbsp;a conserved part of a given protein sequence and&nbsp;(tertiary) structure&nbsp;that can&nbsp;evolve, function, and exist independently of the rest of the protein chain.</pli></ul>

<pul> <li>Evolution :&nbsp;&nbsp;the sequence of events involved in the evolutionary development of a species or taxonomic group of organisms</pli> <li>Epigenetics :&nbsp;the study of heritable changes in gene function that do not involve changes in the&nbsp;DNA sequence</li></ul>

<pul>Allele frequency <li>Frequency(gene allele&nbsp;frequency)<strong> : </strong>the relative frequency of an allele&nbsp;(variant of a gene) at a particular locus&nbsp;in a population,&nbsp;expressed as a fraction or percentage.</pli></ul>

<pul> <li>Gene Regulation :&nbsp;regulation of transcription; controlled by an operon which varies the accessibility of the RNA polymerase to genes being transcribed</pli></ul>

<pul> <li>Homolog :&nbsp;In biology, homology&nbsp;is the existence of shared ancestry between a pair of structures, or genes, in different taxa</pli></ul>

<pul> <li>Taxa :&nbsp;In&nbsp;biology, a&nbsp;taxon&nbsp;(plural&nbsp;taxa;&nbsp;back-formation&nbsp;from&nbsp;<em>taxonomy</em>) is a group of one or more populations of an organism or organisms seen by&nbsp;taxonomists&nbsp;to form a unit.</pli></ul>

<pul> <li>Ortholog :&nbsp;Orthologs are genes in different species that evolved from a common ancestral gene by speciation. Normally, orthologs retain the same function in the course of evolution.</pli></ul>

<pul> <li>Paralog : Paralogs are genes related by duplication within a genome. Orthologs retain the same function in the course of evolution, whereas paralogs evolve new functions, even if these are related to the original one.</pli></ul>

<pul> <li>Locus :&nbsp;in genetics&nbsp;is a fixed position on a chromosome, like the position of a gene or a marker (genetic marker) .</li></pul>