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<p>What is genomics?</p>
<p>Genomics -> Bioinformatics</p>
<p> </p>
<p><T - graph></p>
<p>[[File:T-graph_YK.png|300px|thumb|left|alt text]]</p>
<p>Diverse : Type/Species/People - ex) normal cell vs cancer cell (Horizontal axis in T-graph)</p>
<p>Variability : Gradient of the type (Verticall axis in T-graph)</p>
<p> </p>
<p><Genome + Envirome => Phenome></p>
<p>[[File:Geno+Enviro = Pheno.png|300px|thumb|left|alt text]]</p>
<p>Genome : genetic factor (Korean genome, neurodegenerative genome)</p>
<p>Envirome : environmental factor (Korean enviornment, boxing)</p>
<p> </p>
<p>Phenome : Outcome of the genetic factor and environmental factor (neurodegenerative genome + boxing = parkinson)</p>
<p> </p>
<p>In real world, there are complicated factor about phenome -> It is difficult to predict</p>
<p>-> Solution: 1. Exact data 2. principle 3. big computer</p>
<p> </p>
<p>Sequencing: 1st(ex: sanger) 2nd(ex: shotgun) 3rd(single molecule) 4th(ex: nanopore)</p>
<p>Reference genome: criteria overlapping depth for mapping</p>
<p> </p>
<p>Genome analysis</p>
<p>1. Select sample or species</p>
<p>2. design</p>
<p>3. experiment</p>
<p>ex) Tiger/Whale</p>
<p>1. Tiger is symbolic(cat/lion/tiger) and carnivore / Whale is evolutionally interesting, live very long(average 200 years)</p>
<p>2. design how to..</p>
<p>3. compare the color of fur(white vs orange)</p>
<p> </p>
<p>De Novo(the new) - the first genome not using reference genome </p>
<p> </p>
<p>Glutathion is the antioxidant to reduce the ROS(reactive oxygen species)</p>
<p>Question : Is there any supplements or drugs to increase the level of glutathion? - coffee, green tea, wine....</p>
<p> </p>
