Jihwan Jeon/Assignment
List 30 vocabularies in genomics and explain it with your own words.
1. Genomics
Genomics is a field of biology that studies the whole procedure of biological system from DNA to protein expression.
2. Sequencing
Sequencing is to read out the lists of bases in DNA
3. DNA
DNA is genetic materials that has all information about the organsm.
4. RNA
RNA is genetic materials that helps expression process of DNA to protein. It is made of single stranded sequence of nucleotides.
5. Nucleotide
Nucleotide is basic unit of DNA sequences that is composed of base, glucose and phospate.
6. Base
Base is a chemical group in nucleotide that represent genetic information of DNA sequence
7. Genotype
Genotype is expression of specific character based on DNA sequence
8. Phenotype
Phenotype is expression of specific character based on its real protein expression.
9. Exon
Exon is a part of DNA that has valid information.
10. Intron
Intron is a part of DNA that does not have genetic information
11. Allel
Allel is a complementary pair in chromosome that has same location in sequence.
12. Chromosome
Chromosome is a individual molecule that compose DNA.
13. Genome sequencing project
The project to know total sequence of organism.
14. Sanger method
The primitive method of DNA sequencing using DNA polymerase.
15. Sequence assembly
The technique that assemble short DNA sequnces to get whole DNA sequence
16. DNA annotation
The process that finds out the location of specific gene
17. Epigenomics
One field of genomics that deals with epigenetic process of genetic materials.
18. DNA polymerase
The protein that helps duplication of DNA
19. Mutation
The incidental change of genetic sequence.
20. 5' and 3' terminal
The representation in DNA sequence to prevent misuniderstanding direction
21. Recombinant DNA
DNA that is made manually from RNA sequence
22. Protein expression
The formation of specific protein from DNA sequence
23. Transcription
The formation of mRNA from DNA
24. Translation
The formation of peptide sequence from mRNA.
25. tRNA
tRNA is RNA molecules that interact with mRNA and assign specific animo acid during translation.
26. Post Translation Modification
The modification of animo acids after translation. i.e. hyroxylation, methylation, phosphorylation
27. FASTA
FASTA is a format to express DNA sequence
28. BLAST
BLAST is a algorithm for comparing gene sequences
29. Bioinformatics
One field of genomics that interpret DNA sequences using computational method
30. Allignment
Comparing the sequences based on some specific site.