APC gene
From Biolecture.org
Revision as of 17:32, 16 June 2016 by imported>DONGYOUNG KIM (Created page with "<p><strong>Adenomatous polyposis coli</strong> (APC) also known as <strong>deleted in polyposis 2.5</strong> (DP2.5) is a <a href="https://en.wikipedia.org/wi...")
Adenomatous polyposis coli (APC) also known as deleted in polyposis 2.5 (DP2.5) is a protein that in humans is encoded by the APC gene.The APC protein is a negative regulator that controls beta-catenin concentrations and interacts with E-cadherin, which are involved in cell adhesion. Mutations in theAPC gene may result in colorectal cancer. (By wikipedia)
APC gene has long exon15 and most important region is located in exon15.