PACBIO

PACBIO is a device that Pacific Bioscience introduced in 2004. This device uses a 3rd generation sequencing technique that professor George Church introduced.

 

3rd generation sequencing technique doesn't need duplication process. Also it reads much longer sequence than 2nd generation technique.

 

The technique first breaks DNA down into many nuclotides. Then put them in a semi-conducotr that has may pores that sense the light. Next, this technique read the sequence of DNA using reactivity between the DNA and newly inserted light emitting nucleotides.