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<p><span style="font-size: medium"><b>Principle of Bioinformatics</b></span></p><p><span style="font-size: small"><strong>- </strong>Definition of Bioinformatics.</span></p>
<p>Bioinformatics is an interdisciplinary field that develops methods and software tools for understanding biological data.</p>
<p><span style="font-size: small"><strong>- </strong>History of Bioinformatics.</span></p>
<p>Paulien Hogeweg and Ben Hesper coined the term B<i>ioinformatics</i> in 1970 to refer to the study of information processes in biotic system. This definition placed Bioinformatics as a field parallel to Biophysics or Biochemistry.</p>
<p><span style="font-size: small"><strong>- </strong>Structural Bioinformatics.</span></p>
<p>Protein structure prediction is another important applicaiton of bioinformatics. The amino acid sequence of a protein, the so-called primary structure, can be easily determined from the sequence on the gene that codes for it.</p>
<p><span style="font-size: small"><strong>- </strong>Goals of Bioinformatics.</span></p>
<p>1. Development and implementation of computer programs that enable efficient access to, use and management of, various types of information.</p>
<p>2. Development of new algorithms and statistical measures that assess relationships among members of large data sets.</p>
<p><span style="font-size: small">- Principles of Bioinformatics.</span></p>
<p>Bioinformatics is a new interdiscipline at the interface of computer science, mathematics and biology. It is naturally characteriized more by the problem domains it addresses than by a foundational set of philosophical or scientific principles.</p>
<p><span style="font-size: small">- References</span></p>
<p>1. <a href="https://en.wikipedia.org/wiki/Bioinformatics">https://en.wikipedia.org/wiki/Bioinformatics</a></p>
<p>2. <a href="http://14.139.227.92/mkumar/Teaching/intro2.pdf">http://14.139.227.92/mkumar/Teaching/intro2.pdf</a></p>