&nbsp; <span style="font-size:20px;"><span style="font-family:Arial,Helvetica,sans-serif;">This summary discusses the measurement of biological age through DNA methylation, known as the epigenetic clock, which reflects changes at the cellular, subcellular, and nuclear levels during aging. Various types of epigenetic clocks have been developed, including Horvath’s clock, Hannum’s clock, DNA PhenoAge, and DNA GrimAge, each with its own distinctions. Correlations between biological age and factors like disease and mortality suggest the potential utility of epigenetic clocks for predicting and identifying age-related risks. Additionally, it summarizes research on interventions that aim to reverse aging, using epigenetic clocks as practical tools for evaluation. The lack of higher-quality information poses a significant challenge, and suggestions are offered to address this limitation. Overall, the review aims to provide a nuanced understanding of epigenetic clocks, offering insights into promoting healthy aging.</span></span><br/> <br/> <br/> <span style="font-size:20px;"><span style="font-family:Arial,Helvetica,sans-serif;">link&nbsp;:&nbsp;[https://www.sciencedirect.com/science/article/pii/S1568163722001854?via=ihub https://www.sciencedirect.com/science/article/pii/S1568163722001854?via%3Dihub]</span></span>