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<p>The standards for SELF are basically set by visible works that LYS did. Detail score of each standard depends on how much LYS achieved the goals of the genomic course from his works. The ppt slide that describes the goal of the genomic course is given above to be clear with the objectivity.</p>
<p>While she was taking this course, she did four things. The first 1st is self-study, which are studying Python by herself, studying gene-aligning method, and studying genome editing with crispr-cas9. The second 2nd is homework, which are making database of aging-related genes and alignment of DNA sequence. The third 3rd is essay about genetic control of aging. The last one is SELF itself. In conclusion, LYS is to be graded A0 as following the SELF.</p>
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<p><strong>AssessmentResults</strong></p> <p> </p>
<p><strong>Self-study (40/40)</strong></p>
<p>LYS made self-study folder on her Bio-wiki page and arranged what she learned on her own.</p>
<p>She mainly focused on studying of basic programming because she was inexperienced about programming but found programming is widely used in genomics. Therefore, she started Python studying programming study from basic functions, conditional statement to sort, search method and regular expressions.</p>
<p>In addition, she studied gene-aligning method by herself, using FASTAQ file and Mobaxterm.</p> <p>Also, she found some videos about genome editing with crispr-cas9 to know the CRISPR-Cas9 method for genome editing. She found that is ’s a powerful new technology with many applications in biomedical research, including the potential to treat human genetic disease.</p>
<p>This voluntary learning reflects how much LYS independently works on the subjects that she was curious about and proves LYS successfully learned how to learn.</p>
<p>Figure 5.Self-study: gene alignment-2</p>
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<p><strong>Homework (15/20)</strong></p>
<p>Homework was given, which is producing a database of aging-related genes. The purpose of the homework was to make students think themselves about relevance between aging and gene, which is a necessary process to become a scientist and LYS successfully finished the homework. However, she didn’t do all homeworks therefore she couldn’t get full points. <img src="file:///C:/Users/이예성/AppData/Local/Temp/msohtmlclip1/01/clip_image010.png" style="height:277px; width:602px" /></p>
<p>Therefore, LYS gets 15points out of 20points in the ‘Homework’ section.</p> <p><img src="file:///C:/Users/이예성/AppData/Local/Temp/msohtmlclip1/01/clip_image010.png" style="height:277px; width:602px" /></p> <p>Figure 6. Yesung’s homework: producing Aging-related gene database.</p>
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<p><strong>Essay (15/20)</strong></p>
<p>The essay is written about the topic that LYS was curious about during self-study, which is aging-gene and life span. She was wondering about what determines how long a person will live. So she found one article and wrote review about the subject, which is about a single gene , named daf-2, playing a large role in the length of the human life span.</p>
<p>According to her essay, a single gene could dramatically regulate how long an organism lived, thus opening the door to new hypotheses about modifying life span through genetic manipulation. The responsible These are gene is called daf-2 and the transcription factor DAFdaf-16. DAFdaf-16 controls the expression of a battery of genes, many of which have small effects on lifespan (promoting either aging or longevity) in <em>Caenorhabditis elegans.</em>This activation of DAF-16 (caused by the absence of a phosphate group) is a necessary step toward life span extension</p>
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<p>Figure 7. LYS’s essay: Aging versus long life: the molecules involved</p>
<p>The fact that LYS worked on sincere question arisen in his thought proves that LYS successfully learned how to learn the scientific phenomena and the function of genes<img src="file:///C:/Users/이예성/AppData/Local/Temp/msohtmlclip1/01/clip_image014. However, to look at works of LYS thoroughly, there are no active experiment research since LYS didn&rsquojpg" style="height:22px;t conduct any experiment about putting her thought into practice. Therefore, it is hard to say that LYS perfectly achieved the goal of the course when it comes to essaywidth:602px" /></p> <p><img src="file:///C:/Users/이예성/AppData/Local/Temp/msohtmlclip1/01/clip_image015.jpg" style="height:196px; width:602px" /></p>
<p>As a result, LYS deducted 5points (1/4 of 20, the max point of Figure 8. Essay) by lack of performance of active experiment in essay and gets 15points out of 20points in the ‘Essay’ section.LYS on Bio wiki</p>
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<p><img src="file:///C:/Users/이예성/AppData/Local/Temp/msohtmlclip1/01/clip_image014The fact that LYS worked on sincere question arisen in his thought proves that LYS successfully learned how to learn the scientific phenomena and the function of genes.jpg" style="height:22px; width:602px" />However, to look at works of LYS thoroughly, there are no active experiment research since LYS didn rsquo;t conduct any experiment about putting her thought into practice. Therefore, it is hard to say that LYS perfectly achieved the goal of the course when it comes to essay.</p>
<p><img src="file:As a result, LYS deducted 5points (1///C:/Users/이예성/AppData/Local/Temp/msohtmlclip1/01/clip_image0154 of 20, the max point of Essay) by lack of performance of active experiment in essay and gets 15points out of 20points in the ‘Essay’ section.jpg" style="height:213px; width:654px" /></p>
<p>Figure 8. Essay of LYS on Bio wiki </p>
<p><strong>SELF (20/20)</strong></p>
<p>Table 3. Objective conversion from letter to point.</p>
<p>LYS gets 90points 90 points from the assessment. To correspond it to the letter grade, LYS made letter grade table which shows the most objective way of conversion. In UNIST, 4.3 is the perfect score and deducted by 0.3 when the sign is changed, and deducted by 0.4 when the letter is changed as shown above. Then it is reasonable to convert 0.3 into 6.98points and 0.4 into 9.30points when 4.3 and 0 are set as 100points and 0points. The 90points 90 points which LYS gets is corresponded to letter A0.</p>
<p>In conclusion, LYS is to be graded A0 as following the SELF.</p>
<p>SELF</p>
<p><a href="http://biolecture.org/index.php/Yesung%27s_Self_evaluation">http://biolecture.org/index.php/Yesung%27s_Self_evaluation</a></p> <p> </p>
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