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<p> In eQTL mapping, gene expression data are used as a phenotype on which to base quantitative genetic association mapping (Fig. 1),</p> <p>the rationale being that gene expression is a more proximal, intermediate quantitative phenotype to the underlying genetic risk than heterogeneous behavioural or anatomical phenotypes.</p>
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<p> <img alt="" src="/ckfinder/userfiles/images/nature08537-f1_2.jpg" style="height:511px;width:800px" /></p>
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