<p>9/23 &nbsp; &nbsp;question</p>

<pstyle="margin-left: 40px;">Regarding phylogenetic tree</p>

<pstyle="margin-left: 40px;">My question: How can we know the divergence time?</p>

<pstyle="margin-left: 40px;">-&gt; We cannot know the exact divergence time so this tree can be wrong.</p>

<pstyle="margin-left: 40px;">&nbsp;We can just &nbsp;compare&nbsp;their genes and roughly estimate it by their genetic difference.</p>

<pstyle="margin-left: 40px;">Also we can use fossil record.</p>

<pstyle="margin-left: 40px;">&nbsp;</p>

<p style="margin-left: 40px;">Jhong said it is a good question.</p> <p style="margin-left: 40px;">&nbsp;</p> <p>10/8 &nbsp; &nbsp;2 questions</p>

<pstyle="margin-left: 40px;">My question: How do we know whether the sequence is right or wrong by linking fragments?</p> <p style="margin-left: 40px;">-&gt; 1.Sequence genome multiple times to reduce error.</p> <p style="margin-left: 40px;">2. Experimentally we can seperate each DNA&nbsp;in a well then we know certain fragemnts are come from 1 DNA. And linking them.</p>

<pstyle="margin-left: 40px;">-&gtnbsp; 1.Sequence genome multiple times to reduce error.</p>

<pstyle="margin-left: 40px;">2. Experimentally we can seperate each DNA&nbsp;in Jhong said it is a well then we know certain fragemnts are come from 1 DNA. And linking themgood question.</p>

<pstyle="margin-left: 40px;">My question: When using second method, we can know that they are all in one line but how can we control the distance between each fragment?&nbsp;</p>

<p>style="margin-&gtleft: 40px; By ">My question: When using long sequencesecond method, computer we can link them easily know that they are all in one line but if it is not, how can we can do pair-end sequencing.control the distance between each fragment?</p>

<pstyle="margin-left: 40px;">-&gt; By using long scaffold and fill the gap. If the gaps fill sequence, computer can link them easily, it means but if it is accurate. Alsonot, compare with other species&#39;s genome by using CEGMA or BUSCOwe can do pair-end sequencing.</p>

<pstyle="margin-left: 40px;">By using long scaffold and fill the gap. If the gaps fill easily, it means it is accurate. Also, compare with other species&#39;s genome by using CEGMA or BUSCO.</p> <p style="margin-left: 40px;">&nbsp;</p> <p style="margin-left: 40px;">Jhong said it is a good question.</p> <p style="margin-left: 40px;">&nbsp;</p>

<pstyle="margin-left: 40px;">Regarding the question that &#39;what topic or question would you make relating with vulture genomics?&#39;</p>

<pstyle="margin-left: 40px;">My answer: &nbsp;their digestive system, which&nbsp;can digest rotten meat. Also their habitat because they can live in harsh environment.</p>

<pstyle="margin-left: 40px;">My question: If we inject certain genes to different species, that species can get same property that we inject?&nbsp;</p>

<p>style="margin-&gtleft: 40px; It can">Jhong said their digestive system could be good topic. BecauseIn case of habitat, most of sequence it also can be a topic but is similar although they are different speciesnot much related with human.</p>

<pstyle="margin-left: 80px;">&nbsp;</p> <p style="margin-left: 40px;">My question: If we inject certain genes to different species, that species can get same property that we inject?</p> <p style="margin-left: 40px;">-&gt; It can. Because, most of sequence is similar although they are different species.</p> <p style="margin-left: 40px;">&nbsp;</p>

<pstyle="margin-left: 40px;">Regarding oncomics, after seeing the data about genome squencing&nbsp;.</p>

<pstyle="margin-left: 40px;">My question: &#39;Why men&#39;s cancer mortality is higher than women although Y chromosome does not occur mutation in that data?&nbsp;&#39;</p>

<pstyle="margin-left: 40px;">-&gt; In case of men, they have X, Y chromosomes so, it can be because their X chromosome is unstable.&nbsp;</p>

<pstyle="margin-left: 40px;">(However, this is different that I estimated in my essay that I already had written. But Jhong also said it is his guess.)</p>

<pstyle="margin-left: 40px;">&nbsp;</p>

<pstyle="margin-left: 40px;">Regarding telomere sequence, &#39;Why the sequence is TTAGGG?&#39;</p> <p style="margin-left: 40px;">My Answer:</p>

<pstyle="margin-left: 40px;">It can be related with stop codon. Because, TAG among the T<strong>TAG</strong>GG sequence is stop codon and by using it as a template, <strong>My Answer:AAT</strong>CCC in different strand.</p>

<pstyle="margin-left: 40px;">It can be related with stop codon. BecauseSo, TAG among by the T<strong>TAG</strong>GG sequence opposite direction, TAA is also stop codon and by using it as a template, <strong>AAT</strong>CCC in different strand.</p>

<pstyle="margin-left: 40px;">So, by the opposite direction, TAA is also stop codon.&nbsp;</p>

<pstyle="margin-left: 40px;">Jhong said it is a good estimation.&nbsp;</p>

<pstyle="margin-left: 40px;">Regarding telomere length, in animal, if you have a longer telomere, it means die earlier. (By comparing mouse and human.)&nbsp;</p>

<pstyle="margin-left: 40px;">Regarding telomere length, in animal, if you have a longer telomere, it means die earlier. (By comparing mouse and human.)&nbsp;</p>

<pstyle="margin-left: 40px;">My answer:</p>

<pstyle="margin-left: 40px;">Although the telomere length is longer but the cell cycle time can be different.</p>

<pstyle="margin-left: 40px;">&nbsp;</p>

<pstyle="margin-left: 40px;">Jhong siad it could be a reason because, they can die early if the cell cycle time is short eventhough they have longer telomere.&nbsp;</p>

<pstyle="margin-left: 40px;">&nbsp;</p>