<p><span style="font-size:14px">Comparative genomics is a research field of biological research in which biology&nbsp;that compares&nbsp;the genomic features of different organisms are compared. Whole or large parts of genomes resulting from genome projects are compared in order&nbsp;to study basic biological similarities understand not only similar and differences as well as different features&nbsp;but also&nbsp;evolutionary relationships between organisms. Common features characteristics&nbsp;of two organisms will &nbsp;often be encoded within the DNA in sequence&nbsp;that is evolutionarily &nbsp;conserved between them. Therefore, comparative genomic approaches start with making some form of alignment of genome sequences and looking can be used for orthologous sequences aligning,&nbsp;finding orthologs in the aligned genomes sequence, and checking to what extent those sequences are existence of conservedsequence between organisms.</span></p>

<p><span style="font-size:14px">Evolutionary theory is also the The theoretical foundation base of comparative genomics&nbsp;is evolutionary theory, and at &nbsp;the same time the results of &nbsp;comparative genomics unprecedentedly enriched &nbsp;enrich&nbsp;and developed develop&nbsp;the theory of evolution. Similarity of related genomes is the basis of comparative genomics. &nbsp;Two creatures which have share&nbsp;a recent common ancestor, the species &nbsp;genome difference genomes &nbsp;between them were have&nbsp;evolved from ancestors&rsquo; genome, the .&nbsp;The closer the two organisms on the evolutionary stagesdivergence, the higher their genome correlatedcorrelation is.</span></p>

<p><span style="font-size:14px">Computational From the large-scale genomic database,&nbsp;computational tools for analyzing analysis of&nbsp;sequences and complete complement of&nbsp;genomes are developed &nbsp;quickly due to the availability of large amount of genomic datagenerated. &nbsp;Internet-based genome browsers provide many useful tools for investigating database&nbsp;provides platforms to&nbsp;study&nbsp;genomic sequences due to ,&nbsp;integrating all sequence-based biological information on genomic regions.</span></p>