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<p style="margin: 0cm 0cm 8pt"><font size="+0"><u><span style="font-size: 16pt; line-height: 107%">Course Description</span></u><span style="font-size: 16pt; line-height: 107%"> for BME324, Genomics</span></font></p>
<p style="margin: 0cm 0cm 8pt"><span style="font-size: 11pt; line-height: 107%"><font size="+0">by Jong Bhak (jongbhak@gmail.com)</font></span><span><br />
<font size="+0"><font size="2"><br />
</font></font></span><span style="font-size: 11pt; line-height: 107%"><font size="+0">Genomics is the new name for genetics that encompasses not only traditional<br />
genetics research and technology topics but also includes information technology, systems biology, high throughput biodata generation, processing, and analyses. It covers areas such as sequencing, DNA synthesis, and genome writing and editing.<br />
Genomics course requires the students to have been exposed to general<br />
biology, data processing, statistics, mathematics, and computer science.<br />
The genomic research can be largely divided into experimental and informatic<br />
parts. The course will not cover hands-on experiments due to space limitation.<br />
Students who took this subject will be able to understand life in terms of information processing with much knowledge on how to use technologies to solve problems such as curing cancer and aging.<br />
The topics of genomics include:<br />
<br />
1. What is life, information, and the universe? (as information processing objects)<br />
2. What is Omics? (as an approach of understanding life)<br />
3. What is 'Big data' in biology?<br />
4. How molecules and cells propagate in the universe?<br />
5. Genome reading and writing</font></span></p>
<p style="margin: 0cm 0cm 8pt"><span style="font-size: 11pt; line-height: 107%"><font size="+0">6. Curing Cancer using genomics (Oncomics)</font></span></p>
<p style="margin: 0cm 0cm 8pt"><span style="font-size: 11pt; line-height: 107%"><font size="+0">7. Curing Aging using genomics (Geromics)</font></span></p>
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<div style="margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all"><span style="color: black; line-height: 160%"><font size="2">Text</font></span></div>
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<div style="margin: 0cm 0cm 8pt; line-height: normal; -ms-word-break: keep-all"><span style="color: black"><font size="2">Title</font></span></div>
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<div style="margin: 0cm 0cm 8pt; line-height: normal; -ms-word-break: keep-all"><span style="color: red"><font size="2">Introduction to Genomics </font></span></div>
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<div style="margin: 0cm 0cm 8pt; line-height: normal; -ms-word-break: keep-all"><span style="color: red"><font size="2">Arthur M. Lesk,</font></span></div>
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<div style="margin: 0cm 0cm 8pt; line-height: normal; -ms-word-break: keep-all"><span style="color: black"><font size="2">ISBN</font></span></div>
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<div style="margin: 0cm 0cm 8pt; line-height: normal; -ms-word-break: keep-all"><span style="color: black"><font size="2">Remarks</font></span></div>
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<div style="margin: 0cm 0cm 8pt; line-height: normal; -ms-word-break: keep-all"><span style="color: black"><font size="2"> </font></span><span style="color: red"><font size="2">Oxford University Press</font></span></div>
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<div style="margin: 0cm 0cm 8pt; line-height: normal; -ms-word-break: keep-all"><span style="color: black"><font size="2">Course Reserves Designation</font></span></div>
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<div style="margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all"><span style="color: black; line-height: 160%"><font size="2">References</font></span></div>
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<p style="margin: 0cm 0cm 8pt"><b><span style="font-size: 11pt; line-height: 107%; serif: ">The Atom of Evolution</span></b><span style="font-size: 11pt; line-height: 107%; serif: ">. <strong> </strong>Genomics & Informatics, December <span style="color: red">2004</span>, 2(4):167-173.</span></p>
<div style="margin: 0cm 0cm 8pt"><strong><span style="color: black"><font size="2"> </font></span></strong></div>
<p style="margin: 0cm 0cm 8pt"><strong><span style="color: black"><font size="2">Genomic profile analysis of diffuse-type gastric cancers </font></span></strong></p>
<div style="margin: 0cm 0cm 8pt"><strong><i><span style="color: black"><font size="2">Genome Biology</font></span></i></strong><strong><span style="color: black"><font size="2">, </font></span></strong><strong><span style="color: red"><font size="2">2014</font></span></strong></div>
<div style="margin: 0cm 0cm 8pt"><strong><span style="font-weight: normal; color: black"><font size="2"> </font></span></strong></div>
<p style="margin: 0cm 0cm 8pt"><strong><span style="color: black"><font size="2">Minke whale genome and aquatic adaptation in cetaceans. </font></span></strong></p>
<div style="margin: 0cm 0cm 12pt"><i><span style="serif: "><font size="2">Nature Genetics</font></span></i><span style="serif: "><font size="2">, </font><font size="2"> </font><span style="color: red"><font size="2">2013</font></span><font size="2">. (24</font><sup><font size="2">th</font></sup><font size="2"> Nov 2013)</font></span></div>
<div style="margin: 0cm 0cm 8pt"><strong><span style="font-weight: normal; color: black"><font size="2"> </font></span></strong></div>
<p style="margin: 0cm 0cm 8pt"><strong><span style="color: black"><font size="2">Tiger genome and comparative analysis with lion and snow leopard genomes.</font></span></strong></p>
<div style="margin: 0cm 0cm 12pt"><i><span style="serif: "><font size="2">Nature Communications</font></span></i><span style="serif: "><font size="2">, </font><font size="2"> </font><span style="color: red"><font size="2">2013</font></span><font size="2">. Sep. 17</font><sup><font size="2">th</font></sup><font size="2">. </font></span></div>
<div style="margin: 0cm 0cm 12pt"><span style="serif: "><font size="2"> </font></span></div>
<div style="vertical-align: baseline; background: white; margin: 4.5pt 0cm; line-height: 13.5pt"><b><font size="6"><span style="font-size: 11pt; color: black; serif: ">Whole transcriptome analyses of six thoroughbred horses before and after exercise using RNA-Seq</span></font></b></div>
<div style="vertical-align: baseline; background: white; margin: 4.5pt 0cm; line-height: 13.5pt"><b><font size="6"><i><span style="font-size: 11pt; background: white; color: black; serif: ">BMC Genomics</span></i><span style="font-size: 11pt; background: white; color: black; serif: ">. </span><span style="font-size: 11pt; background: white; color: red; serif: ">2012 Sep </span><span style="font-size: 11pt; background: white; color: black; serif: ">12;13:473. doi: 10.1186/1471-2164-13-473.</span></font></b></div>
<div style="margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all"> </div>
<div style="margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all"><span style="font-size: 12pt; color: black; line-height: 160%">Weekly Schedule</span></div>
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<div style="text-align: center; margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 160%"><font size="2">Week</font></span></div>
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<div style="text-align: center; margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 160%"><font size="2">Contents</font></span></div>
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<div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">01</font></span></div>
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<div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">What is the Universe? </font></span></div>
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<div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">02</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
<div style="text-align: left; margin: 0cm 0cm 8pt; text-indent: 5pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2">What is Life?</font></span></div>
</td>
</tr>
<tr style="height: 35.65pt">
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
<div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">03</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
<div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">What is Science?</font></span></div>
</td>
</tr>
<tr style="height: 35.65pt">
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
<div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">04</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
<div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">What is Biology? </font></span></div>
</td>
</tr>
<tr style="height: 35.65pt">
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
<div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">05</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
<div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">What is Information?</font></span></div>
</td>
</tr>
<tr style="height: 35.65pt">
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
<div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">06</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
<div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">What is Programming?</font></span></div>
</td>
</tr>
<tr style="height: 35.65pt">
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
<div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">07</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
<div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">What is Bioinformatics? </font></span></div>
</td>
</tr>
<tr style="height: 35.65pt">
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
<div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">08</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
<div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">What is Omics?</font></span></div>
</td>
</tr>
<tr style="height: 35.65pt">
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
<div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">09</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
<div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">What is Genomics?</font></span></div>
</td>
</tr>
<tr style="height: 35.65pt">
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
<div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">10</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
<div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">What is Evolution?</font></span></div>
</td>
</tr>
<tr style="height: 35.65pt">
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
<div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">11</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
<div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">What is Sequence?</font></span></div>
</td>
</tr>
<tr style="height: 35.65pt">
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
<div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">12</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
<div style="text-align: left; margin: 0cm 0cm 8pt; text-indent: 5pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2">What is Cancer?</font></span></div>
</td>
</tr>
<tr style="height: 35.65pt">
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
<div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">13</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
<div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">What is Aging?</font></span></div>
</td>
</tr>
<tr style="height: 35.65pt">
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
<div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">14</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
<div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">Research Report presentation</font></span></div>
</td>
</tr>
<tr style="height: 35.65pt">
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
<div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">15</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
<div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">Research Report presentation</font></span></div>
</td>
</tr>
</tbody>
</table>
</p>
<div style="margin: 0cm 0cm 8pt"><font size="2"> </font></div>
<p>
<table style="border-collapse: collapse" cellspacing="0" cellpadding="0" border="0">
<tbody>
<tr style="height: 12.75pt">
<td style="border-top: rgb(0,0,0) 0px; height: 12.75pt; border-right: rgb(0,0,0) 0px; width: 120.75pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent; border-image: none" width="201">
<div style="margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all"><span style="color: black; line-height: 160%"><font size="2">Grading</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; border-right: rgb(0,0,0) 0px; border-bottom: black 1pt solid; border-left: rgb(0,0,0) 0px; background-color: transparent; border-image: none" width="573">
<div style="margin: 0cm 0cm 8pt"><font size="2"> </font></div>
</td>
</tr>
<tr style="height: 55.85pt">
<td style="border-top: rgb(0,0,0) 0px; height: 55.85pt; border-right: black 1pt solid; width: 505.5pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="843" colspan="2">
<div style="margin: 0cm 0cm 8pt; line-height: 160%; text-indent: 5pt; -ms-word-break: keep-all"><span style="color: red; line-height: 160%"><font size="2">Research report writing and presentation (100%)</font></span></div>
<p style="margin: 0cm 0cm 8pt; line-height: 160%; text-indent: 5pt; -ms-word-break: keep-all"><span style="color: red; line-height: 160%"><font size="2">Each week, before, class, students are asked to submit research reports on genomics topics.</font></span></p>
<p style="margin: 0cm 0cm 8pt; line-height: 160%; text-indent: 5pt; -ms-word-break: keep-all"><span style="color: red; line-height: 160%"><font size="2">The final grade will be given by the quality of research reports and presentations (in English)</font></span></p>
<div style="margin: 0cm 0cm 8pt; line-height: 160%; text-indent: 5pt; -ms-word-break: keep-all"><span style="color: red; line-height: 160%"><font size="2">The important points of grading are:</font></span></div>
<p style="margin: 0cm 0cm 8pt 41pt; line-height: 160%; text-indent: -18pt; -ms-word-break: keep-all"><span style="color: red; line-height: 160%"><span><font size="2">1.</font><span style="font: 7pt "Times New Roman"; font-size-adjust: none; font-stretch: normal"> </span></span></span><span style="color: black; line-height: 160%; serif: "><font size="2">Being scientific in reasoning and presenting</font></span></p>
<p style="margin: 0cm 0cm 8pt 41pt; line-height: 160%; text-indent: -18pt; -ms-word-break: keep-all"><span style="color: red; line-height: 160%"><span><font size="2">2.</font><span style="font: 7pt "Times New Roman"; font-size-adjust: none; font-stretch: normal"> </span></span></span><span style="color: black; line-height: 160%; serif: "><font size="2">Critical thinking level</font></span></p>
<p style="margin: 0cm 0cm 8pt 41pt; line-height: 160%; text-indent: -18pt; -ms-word-break: keep-all"><span style="color: red; line-height: 160%"><span><font size="2">3.</font><span style="font: 7pt "Times New Roman"; font-size-adjust: none; font-stretch: normal"> </span></span></span><span style="color: black; line-height: 160%; serif: "><font size="2">Being independent in thinking</font></span></p>
</td>
</tr>
<tr style="height: 12.75pt">
<td style="border-top: rgb(0,0,0) 0px; height: 12.75pt; border-right: rgb(0,0,0) 0px; width: 120.75pt; border-bottom: rgb(0,0,0) 0px; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent; border-image: none" width="201">
<div style="margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all"><span style="color: black; line-height: 160%"><font size="2"> </font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; border-right: rgb(0,0,0) 0px; border-bottom: rgb(0,0,0) 0px; padding-bottom: 0cm; padding-top: 0cm; padding-left: 0cm; border-left: rgb(0,0,0) 0px; padding-right: 0cm; background-color: transparent; border-image: none" width="573">
<div style="margin: 0cm 0cm 8pt"><font size="2"> </font></div>
</td>
</tr>
</tbody>
</table>
</p>
<div style="margin: 0cm 0cm 8pt"><font size="2"> </font></div>
<p style="margin: 0cm 0cm 8pt"><font size="+0"><u><span style="font-size: 16pt; line-height: 107%">Course Description</span></u><span style="font-size: 16pt; line-height: 107%"> for BME324, Genomics</span></font></p>
<p style="margin: 0cm 0cm 8pt"><span style="font-size: 11pt; line-height: 107%"><font size="+0">by Jong Bhak (jongbhak@gmail.com)</font></span><span><br />
<font size="+0"><font size="2"><br />
</font></font></span><span style="font-size: 11pt; line-height: 107%"><font size="+0">Genomics is the new name for genetics that encompasses not only traditional<br />
genetics research and technology topics but also includes information technology, systems biology, high throughput biodata generation, processing, and analyses. It covers areas such as sequencing, DNA synthesis, and genome writing and editing.<br />
Genomics course requires the students to have been exposed to general<br />
biology, data processing, statistics, mathematics, and computer science.<br />
The genomic research can be largely divided into experimental and informatic<br />
parts. The course will not cover hands-on experiments due to space limitation.<br />
Students who took this subject will be able to understand life in terms of information processing with much knowledge on how to use technologies to solve problems such as curing cancer and aging.<br />
The topics of genomics include:<br />
<br />
1. What is life, information, and the universe? (as information processing objects)<br />
2. What is Omics? (as an approach of understanding life)<br />
3. What is 'Big data' in biology?<br />
4. How molecules and cells propagate in the universe?<br />
5. Genome reading and writing</font></span></p>
<p style="margin: 0cm 0cm 8pt"><span style="font-size: 11pt; line-height: 107%"><font size="+0">6. Curing Cancer using genomics (Oncomics)</font></span></p>
<p style="margin: 0cm 0cm 8pt"><span style="font-size: 11pt; line-height: 107%"><font size="+0">7. Curing Aging using genomics (Geromics)</font></span></p>
<div style="margin: 0cm 0cm 8pt"><span style="font-size: 11pt; line-height: 107%"> </span></div>
<p>
<table style="border-collapse: collapse" cellspacing="0" cellpadding="0" border="0">
<tbody>
<tr style="height: 12.75pt">
<td style="border-top: black 1pt solid; height: 12.75pt; border-right: rgb(0,0,0) 0px; width: 110.95pt; border-bottom: rgb(0,0,0) 0px; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent; border-image: none" width="185" colspan="2">
<div style="margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all"><span style="color: black; line-height: 160%"><font size="2"> </font></span></div>
<div style="margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all"><span style="color: black; line-height: 160%"><font size="2"> </font></span></div>
<div style="margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all"><span style="color: black; line-height: 160%"><font size="2"> </font></span></div>
</td>
<td style="border-top: black 1pt solid; height: 12.75pt; border-right: rgb(0,0,0) 0px; width: 5.6pt; border-bottom: rgb(0,0,0) 0px; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent; border-image: none" width="9">
<div style="margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all"><span style="color: black; line-height: 160%"><font size="2"> </font></span></div>
</td>
<td style="border-top: black 1pt solid; height: 12.75pt; border-right: rgb(0,0,0) 0px; width: 115.55pt; border-bottom: rgb(0,0,0) 0px; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent; border-image: none" width="193">
<div style="margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all"><span style="color: black; line-height: 160%"><font size="2"> </font></span></div>
</td>
<td style="border-top: black 1pt solid; height: 12.75pt; border-right: rgb(0,0,0) 0px; width: 71.9pt; border-bottom: rgb(0,0,0) 0px; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent; border-image: none" width="120">
<div style="margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all"><span style="color: black; line-height: 160%"><font size="2"> </font></span></div>
</td>
<td style="border-top: black 1pt solid; height: 12.75pt; border-right: rgb(0,0,0) 0px; width: 73.5pt; border-bottom: rgb(0,0,0) 0px; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent; border-image: none" width="123" colspan="2">
<div style="margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all"><span style="color: black; line-height: 160%"><font size="2"> </font></span></div>
</td>
<td style="border-top: black 1pt solid; height: 12.75pt; border-right: rgb(0,0,0) 0px; width: 73.8pt; border-bottom: rgb(0,0,0) 0px; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent; border-image: none" width="123">
<div style="margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all"><span style="color: black; line-height: 160%"><font size="2"> </font></span></div>
</td>
</tr>
<tr style="height: 12.75pt">
<td style="border-top: rgb(0,0,0) 0px; height: 12.75pt; border-right: rgb(0,0,0) 0px; width: 451.3pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent; border-image: none" width="752" colspan="8">
<div style="margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all"><span style="color: black; line-height: 160%"><font size="2">Text</font></span></div>
</td>
</tr>
<tr style="height: 15.75pt">
<td style="border-top: rgb(0,0,0) 0px; height: 15.75pt; border-right: rgb(0,0,0) 0px; width: 106.05pt; border-bottom: rgb(0,0,0) 0px; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="177">
<div style="margin: 0cm 0cm 8pt; line-height: normal; -ms-word-break: keep-all"><span style="color: black"><font size="2">Category</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 15.75pt; border-right: rgb(0,0,0) 0px; width: 235.3pt; border-bottom: rgb(0,0,0) 0px; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent; border-image: none" width="392" colspan="5">
<div style="margin: 0cm 0cm 8pt; line-height: normal; -ms-word-break: keep-all"><span style="color: red"><font size="2">Book</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 15.75pt; border-right: black 1pt solid; width: 109.95pt; border-bottom: rgb(0,0,0) 0px; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent; border-image: none" width="183" colspan="2">
<div style="margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all"><span style="color: black; line-height: 160%"><font size="2"> </font></span></div>
</td>
</tr>
<tr style="height: 15.75pt">
<td style="border-top: rgb(0,0,0) 0px; height: 15.75pt; border-right: rgb(0,0,0) 0px; width: 106.05pt; border-bottom: rgb(0,0,0) 0px; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="177">
<div style="margin: 0cm 0cm 8pt; line-height: normal; -ms-word-break: keep-all"><span style="color: black"><font size="2">Title</font></span></div>
</td>
<td style="border-top: rgb(0,0,0); height: 15.75pt; border-right: rgb(0,0,0); width: 235.3pt; border-bottom: rgb(0,0,0); padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0); padding-right: 1.4pt; background-color: transparent" width="392" colspan="5">
<div style="margin: 0cm 0cm 8pt; line-height: normal; -ms-word-break: keep-all"><span style="color: red"><font size="2">Introduction to Genomics </font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 15.75pt; border-right: black 1pt solid; width: 109.95pt; border-bottom: rgb(0,0,0) 0px; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent; border-image: none" width="183" colspan="2">
<div style="margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all"><span style="color: black; line-height: 160%"><font size="2"> </font></span></div>
</td>
</tr>
<tr style="height: 15.75pt">
<td style="border-top: rgb(0,0,0) 0px; height: 15.75pt; border-right: rgb(0,0,0) 0px; width: 106.05pt; border-bottom: rgb(0,0,0) 0px; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="177">
<div style="margin: 0cm 0cm 8pt; line-height: normal; -ms-word-break: keep-all"><span style="color: black"><font size="2">Author</font></span></div>
</td>
<td style="border-top: rgb(0,0,0); height: 15.75pt; border-right: rgb(0,0,0); width: 235.3pt; border-bottom: rgb(0,0,0); padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0); padding-right: 1.4pt; background-color: transparent" width="392" colspan="5">
<div style="margin: 0cm 0cm 8pt; line-height: normal; -ms-word-break: keep-all"><span style="color: red"><font size="2">Arthur M. Lesk,</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 15.75pt; border-right: black 1pt solid; width: 109.95pt; border-bottom: rgb(0,0,0) 0px; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent; border-image: none" width="183" colspan="2">
<div style="margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all"><span style="color: black; line-height: 160%"><font size="2"> </font></span></div>
</td>
</tr>
<tr style="height: 15.75pt">
<td style="border-top: rgb(0,0,0) 0px; height: 15.75pt; border-right: rgb(0,0,0) 0px; width: 106.05pt; border-bottom: rgb(0,0,0) 0px; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="177">
<div style="margin: 0cm 0cm 8pt; line-height: normal; -ms-word-break: keep-all"><span style="color: black"><font size="2">ISBN</font></span></div>
</td>
<td style="border-top: rgb(0,0,0); height: 15.75pt; border-right: rgb(0,0,0); width: 235.3pt; border-bottom: rgb(0,0,0); padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0); padding-right: 1.4pt; background-color: transparent" width="392" colspan="5">
<div style="margin: 0cm 0cm 8pt; line-height: normal; -ms-word-break: keep-all"><span style="color: black"><font size="2"> </font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 15.75pt; border-right: black 1pt solid; width: 109.95pt; border-bottom: rgb(0,0,0) 0px; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent; border-image: none" width="183" colspan="2">
<div style="margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all"><span style="color: black; line-height: 160%"><font size="2"> </font></span></div>
</td>
</tr>
<tr style="height: 15.75pt">
<td style="border-top: rgb(0,0,0) 0px; height: 15.75pt; border-right: rgb(0,0,0) 0px; width: 106.05pt; border-bottom: rgb(0,0,0) 0px; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="177">
<div style="margin: 0cm 0cm 8pt; line-height: normal; -ms-word-break: keep-all"><span style="color: black"><font size="2">Remarks</font></span></div>
</td>
<td style="border-top: rgb(0,0,0); height: 15.75pt; border-right: rgb(0,0,0); width: 235.3pt; border-bottom: rgb(0,0,0); padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0); padding-right: 1.4pt; background-color: transparent" width="392" colspan="5">
<div style="margin: 0cm 0cm 8pt; line-height: normal; -ms-word-break: keep-all"><span style="color: black"><font size="2"> </font></span><span style="color: red"><font size="2">Oxford University Press</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 15.75pt; border-right: black 1pt solid; width: 109.95pt; border-bottom: rgb(0,0,0) 0px; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent; border-image: none" width="183" colspan="2">
<div style="margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all"><span style="color: black; line-height: 160%"><font size="2"> </font></span></div>
</td>
</tr>
<tr style="height: 7.8pt">
<td style="border-top: rgb(0,0,0) 0px; height: 7.8pt; border-right: rgb(0,0,0) 0px; width: 106.05pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent" width="177">
<div style="margin: 0cm 0cm 8pt; line-height: normal; -ms-word-break: keep-all"><span style="color: black"><font size="2">Course Reserves Designation</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 7.8pt; border-right: rgb(0,0,0) 0px; width: 235.3pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent; border-image: none" width="392" colspan="5">
<div style="margin: 0cm 0cm 8pt; line-height: normal; -ms-word-break: keep-all"><span style="color: black"><font size="2"> </font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 7.8pt; border-right: black 1pt solid; width: 109.95pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="183" colspan="2">
<div style="margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all"><span style="color: black; line-height: 160%"><font size="2"> </font></span></div>
</td>
</tr>
<tr style="height: 15.75pt">
<td style="border-top: rgb(0,0,0) 0px; height: 15.75pt; border-right: rgb(0,0,0) 0px; width: 110.95pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent; border-image: none" width="185" colspan="2">
<div style="margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all"><span style="color: black; line-height: 160%"><font size="2">References</font></span></div>
</td>
</tr>
</tbody>
</table>
</p>
<p style="margin: 0cm 0cm 8pt"><b><span style="font-size: 11pt; line-height: 107%; serif: ">The Atom of Evolution</span></b><span style="font-size: 11pt; line-height: 107%; serif: ">. <strong> </strong>Genomics & Informatics, December <span style="color: red">2004</span>, 2(4):167-173.</span></p>
<div style="margin: 0cm 0cm 8pt"><strong><span style="color: black"><font size="2"> </font></span></strong></div>
<p style="margin: 0cm 0cm 8pt"><strong><span style="color: black"><font size="2">Genomic profile analysis of diffuse-type gastric cancers </font></span></strong></p>
<div style="margin: 0cm 0cm 8pt"><strong><i><span style="color: black"><font size="2">Genome Biology</font></span></i></strong><strong><span style="color: black"><font size="2">, </font></span></strong><strong><span style="color: red"><font size="2">2014</font></span></strong></div>
<div style="margin: 0cm 0cm 8pt"><strong><span style="font-weight: normal; color: black"><font size="2"> </font></span></strong></div>
<p style="margin: 0cm 0cm 8pt"><strong><span style="color: black"><font size="2">Minke whale genome and aquatic adaptation in cetaceans. </font></span></strong></p>
<div style="margin: 0cm 0cm 12pt"><i><span style="serif: "><font size="2">Nature Genetics</font></span></i><span style="serif: "><font size="2">, </font><font size="2"> </font><span style="color: red"><font size="2">2013</font></span><font size="2">. (24</font><sup><font size="2">th</font></sup><font size="2"> Nov 2013)</font></span></div>
<div style="margin: 0cm 0cm 8pt"><strong><span style="font-weight: normal; color: black"><font size="2"> </font></span></strong></div>
<p style="margin: 0cm 0cm 8pt"><strong><span style="color: black"><font size="2">Tiger genome and comparative analysis with lion and snow leopard genomes.</font></span></strong></p>
<div style="margin: 0cm 0cm 12pt"><i><span style="serif: "><font size="2">Nature Communications</font></span></i><span style="serif: "><font size="2">, </font><font size="2"> </font><span style="color: red"><font size="2">2013</font></span><font size="2">. Sep. 17</font><sup><font size="2">th</font></sup><font size="2">. </font></span></div>
<div style="margin: 0cm 0cm 12pt"><span style="serif: "><font size="2"> </font></span></div>
<div style="vertical-align: baseline; background: white; margin: 4.5pt 0cm; line-height: 13.5pt"><b><font size="6"><span style="font-size: 11pt; color: black; serif: ">Whole transcriptome analyses of six thoroughbred horses before and after exercise using RNA-Seq</span></font></b></div>
<div style="vertical-align: baseline; background: white; margin: 4.5pt 0cm; line-height: 13.5pt"><b><font size="6"><i><span style="font-size: 11pt; background: white; color: black; serif: ">BMC Genomics</span></i><span style="font-size: 11pt; background: white; color: black; serif: ">. </span><span style="font-size: 11pt; background: white; color: red; serif: ">2012 Sep </span><span style="font-size: 11pt; background: white; color: black; serif: ">12;13:473. doi: 10.1186/1471-2164-13-473.</span></font></b></div>
<div style="margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all"> </div>
<div style="margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all"><span style="font-size: 12pt; color: black; line-height: 160%">Weekly Schedule</span></div>
<p>
<table style="border-collapse: collapse" cellspacing="0" cellpadding="0" border="0">
<tbody>
<tr style="height: 14.7pt">
<td style="border-top: black 1pt solid; height: 14.7pt; border-right: black 1pt solid; width: 40.8pt; background: rgb(214,214,214); border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; border-image: none" width="68">
<div style="text-align: center; margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 160%"><font size="2">Week</font></span></div>
</td>
<td style="border-top: black 1pt solid; height: 14.7pt; border-right: black 1pt solid; width: 410.2pt; background: rgb(214,214,214); border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; border-image: none" width="684">
<div style="text-align: center; margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 160%"><font size="2">Contents</font></span></div>
</td>
</tr>
<tr style="height: 35.65pt">
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
<div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">01</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
<div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">What is the Universe? </font></span></div>
</td>
</tr>
<tr style="height: 35.65pt">
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
<div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">02</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
<div style="text-align: left; margin: 0cm 0cm 8pt; text-indent: 5pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2">What is Life?</font></span></div>
</td>
</tr>
<tr style="height: 35.65pt">
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
<div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">03</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
<div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">What is Science?</font></span></div>
</td>
</tr>
<tr style="height: 35.65pt">
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
<div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">04</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
<div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">What is Biology? </font></span></div>
</td>
</tr>
<tr style="height: 35.65pt">
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
<div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">05</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
<div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">What is Information?</font></span></div>
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<tr style="height: 35.65pt">
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
<div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">06</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
<div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">What is Programming?</font></span></div>
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<tr style="height: 35.65pt">
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
<div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">07</font></span></div>
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<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
<div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">What is Bioinformatics? </font></span></div>
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<tr style="height: 35.65pt">
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
<div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">08</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
<div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">What is Omics?</font></span></div>
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<tr style="height: 35.65pt">
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
<div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">09</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
<div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">What is Genomics?</font></span></div>
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<tr style="height: 35.65pt">
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
<div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">10</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
<div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">What is Evolution?</font></span></div>
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<tr style="height: 35.65pt">
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
<div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">11</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
<div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">What is Sequence?</font></span></div>
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<tr style="height: 35.65pt">
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
<div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">12</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
<div style="text-align: left; margin: 0cm 0cm 8pt; text-indent: 5pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2">What is Cancer?</font></span></div>
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</tr>
<tr style="height: 35.65pt">
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
<div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">13</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
<div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">What is Aging?</font></span></div>
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<tr style="height: 35.65pt">
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
<div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">14</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
<div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">Research Report presentation</font></span></div>
</td>
</tr>
<tr style="height: 35.65pt">
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 40.8pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="68">
<div style="text-align: center; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="center"><span style="color: black; line-height: 107%"><font size="2">15</font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; height: 35.65pt; border-right: black 1pt solid; width: 410.2pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent" width="684">
<div style="text-align: left; margin: 0cm 0cm 8pt; -ms-word-break: keep-all" align="left"><span style="color: black; line-height: 107%; serif: "><font size="2"> </font><font size="2">Research Report presentation</font></span></div>
</td>
</tr>
</tbody>
</table>
</p>
<div style="margin: 0cm 0cm 8pt"><font size="2"> </font></div>
<p>
<table style="border-collapse: collapse" cellspacing="0" cellpadding="0" border="0">
<tbody>
<tr style="height: 12.75pt">
<td style="border-top: rgb(0,0,0) 0px; height: 12.75pt; border-right: rgb(0,0,0) 0px; width: 120.75pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent; border-image: none" width="201">
<div style="margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all"><span style="color: black; line-height: 160%"><font size="2">Grading</font></span></div>
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<td style="border-top: rgb(0,0,0) 0px; border-right: rgb(0,0,0) 0px; border-bottom: black 1pt solid; border-left: rgb(0,0,0) 0px; background-color: transparent; border-image: none" width="573">
<div style="margin: 0cm 0cm 8pt"><font size="2"> </font></div>
</td>
</tr>
<tr style="height: 55.85pt">
<td style="border-top: rgb(0,0,0) 0px; height: 55.85pt; border-right: black 1pt solid; width: 505.5pt; border-bottom: black 1pt solid; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: black 1pt solid; padding-right: 1.4pt; background-color: transparent; border-image: none" width="843" colspan="2">
<div style="margin: 0cm 0cm 8pt; line-height: 160%; text-indent: 5pt; -ms-word-break: keep-all"><span style="color: red; line-height: 160%"><font size="2">Research report writing and presentation (100%)</font></span></div>
<p style="margin: 0cm 0cm 8pt; line-height: 160%; text-indent: 5pt; -ms-word-break: keep-all"><span style="color: red; line-height: 160%"><font size="2">Each week, before, class, students are asked to submit research reports on genomics topics.</font></span></p>
<p style="margin: 0cm 0cm 8pt; line-height: 160%; text-indent: 5pt; -ms-word-break: keep-all"><span style="color: red; line-height: 160%"><font size="2">The final grade will be given by the quality of research reports and presentations (in English)</font></span></p>
<div style="margin: 0cm 0cm 8pt; line-height: 160%; text-indent: 5pt; -ms-word-break: keep-all"><span style="color: red; line-height: 160%"><font size="2">The important points of grading are:</font></span></div>
<p style="margin: 0cm 0cm 8pt 41pt; line-height: 160%; text-indent: -18pt; -ms-word-break: keep-all"><span style="color: red; line-height: 160%"><span><font size="2">1.</font><span style="font: 7pt "Times New Roman"; font-size-adjust: none; font-stretch: normal"> </span></span></span><span style="color: black; line-height: 160%; serif: "><font size="2">Being scientific in reasoning and presenting</font></span></p>
<p style="margin: 0cm 0cm 8pt 41pt; line-height: 160%; text-indent: -18pt; -ms-word-break: keep-all"><span style="color: red; line-height: 160%"><span><font size="2">2.</font><span style="font: 7pt "Times New Roman"; font-size-adjust: none; font-stretch: normal"> </span></span></span><span style="color: black; line-height: 160%; serif: "><font size="2">Critical thinking level</font></span></p>
<p style="margin: 0cm 0cm 8pt 41pt; line-height: 160%; text-indent: -18pt; -ms-word-break: keep-all"><span style="color: red; line-height: 160%"><span><font size="2">3.</font><span style="font: 7pt "Times New Roman"; font-size-adjust: none; font-stretch: normal"> </span></span></span><span style="color: black; line-height: 160%; serif: "><font size="2">Being independent in thinking</font></span></p>
</td>
</tr>
<tr style="height: 12.75pt">
<td style="border-top: rgb(0,0,0) 0px; height: 12.75pt; border-right: rgb(0,0,0) 0px; width: 120.75pt; border-bottom: rgb(0,0,0) 0px; padding-bottom: 1.4pt; padding-top: 1.4pt; padding-left: 1.4pt; border-left: rgb(0,0,0) 0px; padding-right: 1.4pt; background-color: transparent; border-image: none" width="201">
<div style="margin: 0cm 0cm 8pt; line-height: 160%; -ms-word-break: keep-all"><span style="color: black; line-height: 160%"><font size="2"> </font></span></div>
</td>
<td style="border-top: rgb(0,0,0) 0px; border-right: rgb(0,0,0) 0px; border-bottom: rgb(0,0,0) 0px; padding-bottom: 0cm; padding-top: 0cm; padding-left: 0cm; border-left: rgb(0,0,0) 0px; padding-right: 0cm; background-color: transparent; border-image: none" width="573">
<div style="margin: 0cm 0cm 8pt"><font size="2"> </font></div>
</td>
</tr>
</tbody>
</table>
</p>
<div style="margin: 0cm 0cm 8pt"><font size="2"> </font></div>