In 2009, genome sequencing technologies will achieve one person's whole genome per day in terms of DNA fragments sequenced. Personal genomics is a new term that utilizes such fast sequencers. In 2008, the cost for one personal genome is less than $350,000 USD. If the cost goes down below $1,000 USD, the impact of personal genomics is predicted to be the largest ever in biology&nbsp;on common people's life.&nbsp;Reflecting this technological advancement to the society is the PGP (Personal Genome Project), a project to sequence as many people as possible with lowest possible&nbsp;costs </span><span style="FONT-SIZE: 9pt">(Church 2005)</span><span style="FONT-SIZE: 9pt">. At present, Google Inc. and Church group are working together to sequence 100,000 people's genetic regions of DNA. In Saudi Arabia, the government is planning to sequence 100 Arabic people. In Europe, there are various groups of people and nations who have been genotyping the populations. Especially, Iceland has been successful in that effort by utilizing their well-kept genealogical data encompassing 100,000s people. In Asia, Jeongsun Seo of Seoul National University has been working on East Asia Genome Project in the past years. His group collected thousands of samples from Mongolian tribes with a gigantic genealogical tree among them </span><span style="FONT-SIZE: 9pt">(Park et al. 2008; Sung et al. 2008)</span><span style="FONT-SIZE: 9pt">. Seo is said to&nbsp;be sequencing at least 100 Korean genomes in collaboration with Church and Green Cross Inc. of Korea. The aim of Seo's genome project is to produce a resource for the East Asians as well as Koreans. He is presently sequencing at least two Korean people. In China, Beijing Genome Institute has been successful in terms of sequencing. Their first achievement came from a plant genome, rice. After rice, they launched a 100 Han Chinese genome sequencing project. In Nov. 2008, they published their first Chinese genome in a joural, Nature. In Dec. 2008, another Korean group, Lee Gilyeo Cancer and Diabetes Institute (LCDI)&nbsp;and Korean Bioinformation Center (KOBIC) made a Korean genome sequence public. The genome was sequenced by Solexa paired-end sequencer and comparative genomics analyses and SNP data were uploaded as a public resource for everyone.&nbsp;The time taken to analyze the 7.8x Korean genome took only one week using 150 computer CPUs to produce mapping DNA fragments to a reference genome, generate new SNP information, compare with other individual genomes, and map it with 1600 already known phehotype information from the public literature.<br />

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</span></strong><span style="FONT-SIZE: 9pt">These public genome data alongside previously known Craig Venter's and James Watson's mark that full genome sequences are not in academic domain anymore. Anyone who has money and will can sequence human genomes. This 'genomic revolution' will eventually lead to the 'BioRevolution' in terms of making the most essential human information completely mapped and publically available. These are revolutionary because humans can now engineer themselves with a map or a blue print not directly relying on trial and error style conventional evolutionary methods. This indicates that evolution went into a conscious level of driving evolution. It is almost designing the evolution using computers.&nbsp;<br />

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The consequences of 'BioRevolution' where genomic information is utilized by scientists to engineers all kinds of biological processes including evolution itself will bring us the personalized medicine. The essence of personalized medicine is that enzymes in our tissues such as cytochrome P450 have distinct differences among individuals and populations. Certain drugs produce different responses in individuals.&nbsp;<br />

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Alongside and with the associations of eIMBL, A-IMBN, and HVP, a variome project that tries to map Asian population variome was launched in 2008. This was a group effort of Korean researchers who have been interested in genome sequences,&nbsp;SNPs, and CNVs. They have formed a Korean Variome Consortium (KOVAC: <a href="http://variome.kr/"><font color="#0000ff">http://variome.kr</font></a>) and supported AVP as one of the first projects. eIMBL that is the virtual laboratory network of Asia linking key biology groups modeled after EMBL has acquired $80,000 USD in 2008 to support AVP. eIMBL aims to establish a virtual bioinformatics center in Asia Pacific region that links many bioinformation processing scientists in Asia.<br />

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Bioinformatics is the key in personal genome projects and variome projects. Bioinformatics is not a set of tools but it is a proper scientific discipline. It regards life as a gigantic information processing phenomenon and tries to map its components and to model the emerging networks of the components. Bioinformatics in 2008 is driving biology into an information science. Most biology researches are now with massive amount of data that cannot be processed by hand. Nearly all the biological research outcomes in the next&nbsp;five years will have some form of high throughput data such as genome sequences, microarray data, proteome analyses, SNPs, epigenome chips, and large scale phenotype mapping. Bioinformatics tools in genomics and variomics can be found from various internet resources. There are various bioinformatics hubs such as NCBI (National Center for Biotechnology Information), EBI (European Bioinformatics Institute), DDBJ (Databank of Japan), and KOBIC.&nbsp;Some&nbsp;others are: Bioinformatics Organization (<a href="http://bioinformatics.org/"><font color="#0000ff">http://Bioinformatics.Org</font></a>), EMBnet (<a href="http://www.embnet.org/"><font color="#0000ff">http://www.embnet.org/</font></a>), and&nbsp;The International Society for Computational Biology (<a href="http://iscb.org/"><font color="#0000ff">http://iscb.org</font></a>). The following are major bioinformatics journals:<br />

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</span><strong><span style="FONT-SIZE: 9pt">Mapping expression using DNA sequencing</span></strong><span style="FONT-SIZE: 9pt"><br />

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<div><strong><font size="2">Acknowledgements</font></strong><br />

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