05.13 class

bioinformatics is about mapping - but you have to choose the right parameter!
old map is not accurate
however it helps people to explore

what is life?
life is a set of switches (professor's thought)

bioinformatics is the study of compelxity (thigs with a lot of #s, big data)
three fundamental elements in bioinformatics : energy, information in time

6 domains of bioinformatics
sequence, structure, expression,interaction, function, network

2 (paired) is the most important for the DNA structure - Creek & Watson
(Linus Pauling suggested tri-helix structure)

Alan Turing - he proposed that the world can be computed

representation of data - sequence, structure, expression, "pathways"(directional), function, network

you have to memorize all amino acids!
species-genus-family-(superfamily)-order-class-phlym-kingdom

mass production of data (high throughput technology)
-about 2004, human genome project finished
DNA/RNA microarray
structural genomics
proteomics (mass spectrometry)
interactomics (Y2H(yeast two hybridize), protein chips based)
sequencing (5 minutes for sequencing whole human genome)