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Description of Genomics course

Revision as of 20:51, 19 April 2015 by imported>S

Course Description for BME324, Genomics

by Jong Bhak (jongbhak@gmail.com)

Genomics is the new name for genetics that encompasses not only traditional
genetics research and technology topics but also includes information technology, systems biology, high throughput biodata generation, processing, and analyses.

It covers areas such as sequencing, DNA synthesis, and genome writing and editing.
Genomics course requires the students to have been exposed to general
biology, data processing, statistics, mathematics, and computer science.
The genomic research can be largely divided into experimental and informatic
parts. The course will not cover hands-on experiments due to space limitation.
Students who took this subject will be able to understand life in terms of information processing
with much knowledge on how to use technologies to solve problems such as curing cancer and aging.

The topics of genomics include:

1. What is life, information, and the universe?  (as information processing objects)
2. What is Omics? (as an approach of understanding life)
3. What is 'Big data' in biology?
4. How molecules and cells propagate in the universe?
5. Genome reading and writing

6. Curing Cancer using genomics (Oncomics)

7. Curing Aging using genomics (Geromics)

 

 
 
 
 
 
 
 
 
Text
Category
Book
 
Title
 
Author
Arthur M. Lesk,
 
ISBN
 
 
Remarks
 Oxford University Press
 
Course Reserves Designation
 
 
References

The Atom of Evolution.  Genomics & Informatics, December 2004, 2(4):167-173.

 

Genomic profile analysis of diffuse-type gastric cancers

Genome Biology, 2014
 

Minke whale genome and aquatic adaptation in cetaceans.

Nature Genetics,  2013. (24th Nov 2013)
 

Tiger genome and comparative analysis with lion and snow leopard genomes.

Nature Communications,  2013. Sep. 17th.
 
Whole transcriptome analyses of six thoroughbred horses before and after exercise using RNA-Seq
BMC Genomics.  2012 Sep 12;13:473. doi: 10.1186/1471-2164-13-473.
 
Weekly Schedule

Week
Contents
01
 What is the Universe?
02
What is Life?
03
 What is Science?
04
 What is Biology?
05
 What is Information?
06
 What is Programming?
07
 What is Bioinformatics?
08
 What is Omics?
09
 What is Genomics?
10
 What is Evolution?
11
 What is Sequence?
12
What is Cancer?
13
 What is Aging?
14
 Research Report presentation
15
 Research Report presentation

 

Grading
 
Research report writing and presentation (100%)

Each week, before, class, students are asked to submit research reports on genomics topics.

The final grade will be given by the quality of research reports and presentations (in English)

The important points of grading are:

1.      Being scientific in reasoning and presenting

2.      Critical thinking level

3.      Being independent in thinking