Minsu Kim / VOCA
Active Site : The specific portion of an enzyme that attaches to the substrate by means of weak chemical bonds.
Bioinformatics : an interdisciplinary field that develops methods and software tools for understanding biological data. As an interdisciplinary field of science, bioinformatics combines Computer Science, Biology, Mathematics, and Engineering to analyze and interpret biological data.
BLAST : Basic Local Alignment Search Tool is an algorithm for comparing primary biological sequence information, such as the amino-acid sequences of proteins or the nucleotides of DNA sequences.
Central dogma : The central dogma of molecular biology is an explanation of the flow of genetic information within a biological system.
DNA(Duplication) → RNA → Protein
Protein Domain : a conserved part of a given protein sequence and (tertiary) structure that can evolve, function, and exist independently of the rest of the protein chain.
Evolution : the sequence of events involved in the evolutionary development of a species or taxonomic group of organisms
Allele frequency(gene frequency) : the relative frequency of an allele (variant of a gene) at a particular locus in a population, expressed as a fraction or percentage.
Gene Regulation : regulation of transcription; controlled by an operon which varies the accessibility of the RNA polymerase to genes being transcribed
Homolog : In biology, homology is the existence of shared ancestry between a pair of structures, or genes, in different taxa
Taxa : In biology, a taxon (plural taxa; back-formation from taxonomy) is a group of one or more populations of an organism or organisms seen by taxonomists to form a unit.
Ortholog : Orthologs are genes in different species that evolved from a common ancestral gene by speciation. Normally, orthologs retain the same function in the course of evolution.
Paralog : Paralogs are genes related by duplication within a genome. Orthologs retain the same function in the course of evolution, whereas paralogs evolve new functions, even if these are related to the original one.