Yesung's homework 1st

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Revision as of 23:58, 2 December 2018 by imported>Yesung Lee (Tacutu, R., Thornton, D., Johnson, E., Budovsky, A., Barardo, D., Craig, T., Diana, E., Lehmann, G., Toren, D., Wang, J., Fraifeld, V. E., de Magalhaes, J. P. (2018) "Human Ageing Genomic Resources: n)
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GenAge ID symbol aliases name entrez gene id uniprot why band location start location end orientation acc promoter acc orf acc cds references orthologs
1 GHR GHBP growth hormone receptor 2690 GHR_HUMAN mammal 5p13-p12 42423775 42721878 1   NM_000163 NP_000154 12933651,10875265,2233903,10895047,12392795,14698816,15295107,15308771,15342923,8612101,15466429,15536017,15582293,15919742,15621211,16129095,15985475,16524678,16682650,16939484,17183314,17173483,19234595,7664676,16282554,16339324,21325617,19286975,9371826,11213276,16799137,17301033,11950656,24517230,25274507,27732088,27688483,26268661 Ghr;Mus musculus,Ghr;Rattus norvegicus,ghrb;Danio rerio,ghra;Danio rerio
2 GHRH GHRF growth hormone releasing hormone 2691 SLIB_HUMAN mammal 20q11.2 37251086 37256896 -1 HS_GHRH NM_021081 NP_066567 ####### Ghrh;Mus musculus,Ghrh;Rattus norvegicus
3 SHC1 p66 ShcA SHC SHC (Src homology 2 domain containing) transforming protein 1 6464 SHC1_HUMAN mammal 1q21 1.55E+08 1.55E+08 -1   NM_003029 NP_003020 11884717,12483226,10580504,12032825,12571362,14530863,14501182,12763525,7564569,14698816,15078873,15036421,15295107,15308771,15466429,15582293,15339240,15930121,16439820,16763167,18413607,18838380,19327338,19892704,20085805,20624962,16026332,15992607,24336818,25257068,18065182,26968134 Shc1;Mus musculus,Shc;Drosophila melanogaster,Shc1;Rattus norvegicus,shc1;Danio rerio,shc-1;Caenorhabditis elegans
4 POU1F1 GHF-1 POU1F1a PIT1 POU class 1 homeobox 1 5449 PIT1_HUMAN mammal 3p11 87259633 87276587 -1   NM_000306 NP_000297 ####### Pou1f1;Mus musculus,Pou1f1;Rattus norvegicus,pou1f1;Danio rerio
5 PROP1   PROP paired-like homeobox 1 5626 PROP1_HUMAN mammal 5q35.3 1.78E+08 1.78E+08 -1   NM_006261 NP_006252 ############################################################################################################################################################################################################################################################### Prop1;Mus musculus,CG32532;Drosophila melanogaster,unc-42;Caenorhabditis elegans,Prop1;Rattus norvegicus
6 TP53 p53 LFS1 tumor protein p53 7157 P53_HUMAN mammal,model,cell 17p13.1 7668401 7687550 -1 HS_TP53 NM_000546 NP_000537 9733514,9733515,12142523,12115733,12533509,12032825,11780111,10037601,9218725,12917625,1511730,8051093,9989825,9275177,8654922,12750285,7958916,10973262,11023999,10557106,12719720,10364153,10581258,10761921,15604409,11971980,9353177,12397361,12397362,11348659,16286925,10805805,9171368,12093737,10950866,10877825,11430832,10403253,10805721,11257107,12006491,11672523,11099047,9119221,12509446,1535557,10838077,1552940,12960381,12089551,11934988,14712078,11331603,15078873,12735900,12914700,15013668,11672522,15122989,15044383,15295107,15247009,15308771,14992722,14871929,15383658,14726476,12470840,15466429,15732191,12015983,9529248,15361884,16079796,16054100,10227293,16107615,12882406,16079851,16139996,19620979,16303568,15716376,16302026,16079181,16269335,16439820,16476774,16443777,16391230,16337913,16441846,14713953,15781852,11035041,10691732,15550242,10757812,16728594,11280729,16892051,15152190,12086851,17014852,16652371,16675955,17227869,10710310,17015833,17122775,18242175,17973971,17889646,17637672,17664422,12426394,15928081,19013273,21307849,19718024,19718028,19416129,19239418,18843043,18362329,17546051,20194434,18242663,12665570,10910364,23349637,23602569,23744274,22384090,21522133,12364621,21368881,18204081,18800172,19118192,12629205,9716137,9312059,23973961,16582880,8275084,12914701,15992607,15905204,15147944,15059885,23124852,12447382,17581637,18089799,24341977,16862142,25990896 LOC100910954;Rattus norvegicus,Trp53;Mus musculus,tp53;Danio rerio
7 TERC TR hTR TRC3 DKCA1 PFBMFT2 SCARNA19 telomerase RNA component 7012   mammal,cell 3q26 1.7E+08 1.7E+08 -1   NR_001566 12540856,7544491,9454332,9335332,10089885,2655926,1689810,9849895,9742964,9560153,11850781,10568811,15974869,11574891,10973262,11081503,15098033,15235603,15189140,15312299,15367665,14746617,15466429,15556289,15545322,15326392,12174094,20139977,1582420,23159929,23535734,12426399,16284252,16582880,19915151
8 TERT TRT TP2 TCS1 hEST2 EST2 telomerase reverse transcriptase 7015 TERT_HUMAN cell,functional 5p15.33 1253147 1295069 -1   NM_003219 NP_003210 8978029,9110970,9454332,9288757,11387197,12034875,2655926,12917625,9849895,9742964,7761406,11850781,10568811,12764382,8618017,7727765,8808676,15974869,9600234,11081503,12527915,12827497,9988278,11452025,11277998,12717449,12729798,9328464,12089551,15189140,10440377,15247011,15312299,14726476,10606235,15556289,15574496,15326392,15688016,15814878,16477310,18073191,19571879,19013273,21307849,21113150,20643931,15184392,18843043,15843522,18184747,19580824,1582420,8692840,23349637,23159929,16107853,23744274,23535734,9973199,20605919,15079066,15905204,23535731,19915151,24960204,24749076,25519492 trt1;Schizosaccharomyces pombe,Tert;Mus musculus,Tert;Rattus norvegicus,tert;Danio rerio,EST2;Saccharomyces cerevisiae
9 ATM TEL1 TELO1 ATA ATDC ATC ATD ATM serine/threonine kinase 472 ATM_HUMAN mammal 11q22-q23 1.08E+08 1.08E+08 1   NM_000051 NP_000042 12540856,9733514,9733515,12142523,9363685,10037601,12919958,2005780,9117983,12215213,9353177,2836804,10783165,10802669,10839545,10567403,14712078,15073328,15059890,11331603,14707289,12526788,15122331,15353794,14745549,7777860,15466429,15655364,15733840,8843194,11172010,10691732,12629512,16675955,10435585,21459046,21186350,19524511,20966255,17522062,18804090,20453858,20194434,23019125,23277187,18931659,9405657,9312059,23408054,15345673,15905204,12447382,27732836 Atm;Mus musculus,tefu;Drosophila melanogaster,Atm;Rattus norvegicus,atm;Danio rerio,TEL1;Saccharomyces cerevisiae,atm-1;Caenorhabditis elegans
10 PLAU URK UPA plasminogen activator, urokinase 5328 UROK_HUMAN mammal 10q22.2 73911104 73917500 1 HS_PLAU NM_002658 NP_002649 ####### Plau;Mus musculus,Plau;Rattus norvegicus,svh-1;Caenorhabditis elegans,plaua;Danio rerio,plaub;Danio rerio
11 ERCC2 MAG EM9 MGC102762 MGC126218 MGC126219 TFIIH XPD excision repair cross-complementation group 2 2068 ERCC2_HUMAN mammal 19q13.3 45351391 45370587 -1   NM_000400 NP_000391 ####### rad15;Schizosaccharomyces pombe,Ercc2;Mus musculus,Xpd;Drosophila melanogaster,Ercc2;Rattus norvegicus,ercc2;Danio rerio,RAD3;Saccharomyces cerevisiae,Y50D7A.11;Caenorhabditis elegans
12 ERCC8 CSA CKN1 excision repair cross-complementation group 8 1161 ERCC8_HUMAN human 5q12.1 60873832 60945078 -1 HS_CKN1 NM_000082 NP_000073 ####### ckn1;Schizosaccharomyces pombe,Ercc8;Mus musculus,Ercc8;Rattus norvegicus,ercc8;Danio rerio,RAD28;Saccharomyces cerevisiae
13 WRN RECQL2 RECQ3 Werner syndrome, RecQ helicase-like 7486 WRN_HUMAN human,mammal,cell 8p12 31033262 31173761 1 NM_000553 NM_000553 NP_000544 8602509,11089984,9352493,9288107,9771700,10725663,11087895,12934712,11023999,14527998,147113,12181313,12771022,10364153,12827497,12842909,9117983,14612404,11348659,10373438,12803543,12200042,12937274,14612507,12384494,11598021,10678659,11257107,12750383,9789047,11896071,10806190,10781066,11027336,9681877,14734561,14657658,15026416,15235603,12882351,14618025,15246744,15236770,15292449,15353794,15367665,15200954,15336909,15331638,15466429,15610765,11809708,12202749,15916783,15897889,12024027,16141234,12665521,15733840,16087220,16098926,16287861,16339323,16449207,16405962,10757812,11280729,16723399,16714450,17015833,18203716,20477760,19741171,19077115,20215438,10880505,11279038,9611231,11152456,11889123,14712220,15115755,17996922,23075628,17521388,17301258,25931448 Wrn;Mus musculus,wrn-1;Caenorhabditis elegans,Wrn;Rattus norvegicus,wrn;Danio rerio,SGS1;Saccharomyces cerevisiae
14 LMNA HGPS LMN1 CMD1A LGMD1B PRO1 LMNL1 lamin A/C 4000 LMNA_HUMAN human 1q22 1.56E+08 1.56E+08 1   NM_170707 NP_733821 12714972,11089984,12927431,1944388,12748643,147113,8278403,18381888,9117983,2366592,10080180,8838815,14996929,15688064,12735900,15184648,15145358,15130666,15268757,15353794,15466429,15479179,15750600,15756215,15722103,15980864,16079796,11923874,12235369,10579712,12913070,15843403,15972724,16129833,16248985,16269543,16492728,16461887,16481476,16645051,16511604,16671095,16738054,16801550,17469202,19926845,21346760,18311132,21746928,20961378,18843043,22541428,23019125,23917225,14570852,14755333,20605919,22419169,15317753,18256394,21807766,24639560,24203701,17360326,24843141,25567453,25645366,26248606,27617860,27451905 Lmna;Mus musculus,Lam;Drosophila melanogaster,LamC;Drosophila melanogaster,Lmna;Rattus norvegicus,lmn-1;Caenorhabditis elegans,lmna;Danio rerio
15 IGF1R JTK13 CD221 IGFIR MGC18216 IGFR insulin-like growth factor 1 receptor 3480 IGF1R_HUMAN model 15q26.3 98648539 98964530 1   NM_000875 NP_000866 12483226,12843179,1849352,11292875,11021802,8247153,8402902,14698816,9716402,14628051,8402901,15295107,11133160,15308771,14871929,14745968,15342923,15466429,15565107,15582293,15339240,15888324,15919742,16123266,11172010,16524678,16631585,18316725,22132081,18959478,18615585,10077613,15621218,15345673,14657428,15956778,23898955,16815029,17393577,26469138 Igf1r;Mus musculus,Igf1r;Rattus norvegicus,InR;Drosophila melanogaster,daf-2;Caenorhabditis elegans,igf1ra;Danio rerio,igf1rb;Danio rerio
16 TXN TRX thioredoxin 7295 THIO_HUMAN model,functional 9q31 1.1E+08 1.1E+08 -1 HS_TXN NM_003329 NP_003320 ####### trx1;Schizosaccharomyces pombe,Txn1;Mus musculus,Txn1;Rattus norvegicus,zgc:56493;Danio rerio,txn;Danio rerio,TRX1;Saccharomyces cerevisiae,TRX2;Saccharomyces cerevisiae
17 KL   klotho 9365 KLOT_HUMAN mammal 13q12 33016433 33066145 1   NM_004795 NP_004786 9363890,11792841,12119304,10837414,14701853,12369777,12475907,12362891,15295107,15302783,15466429,15677572,15763166,12669274,12110410,16123266,16186101,16144705,17014852,16436388,17086194,16436465,17690294,17569864,18762812,18678710,19635988,21474560,19077115,14528024,15665504,17452648,11016890,24778222,25037225,17287345,24813892,25673831 Kl;Rattus norvegicus,Kl;Mus musculus,klo-1;Caenorhabditis elegans,klo-2;Caenorhabditis elegans,kl;Danio rerio
18 E2F1 RBP3 RBBP3 E2F transcription factor 1 1869 E2F1_HUMAN cell,downstream 20q11.2 33675486 33686404 -1   NM_005225 NP_005216 ####### E2f1;Mus musculus,E2f1;Drosophila melanogaster,efl-2;Caenorhabditis elegans,E2f1;Rattus norvegicus,E2f1;Rattus norvegicus,E2F1;Danio rerio
19 PTPN11 BPTP3 SH-PTP2 SHP-2 PTP2C SHP2 NS1 protein tyrosine phosphatase, non-receptor type 11 5781 PTN11_HUMAN downstream 12q24 1.12E+08 1.13E+08 1   NM_002834 NP_002825 ####### pyp3;Schizosaccharomyces pombe,Ptpn11;Mus musculus,Ptpn11;Rattus norvegicus,csw;Drosophila melanogaster,ptpn11a;Danio rerio,ptp-2;Caenorhabditis elegans
20 NFKB2 LYT-10 p52 p105 NF-kB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 4791 NFKB2_HUMAN functional 10q24 1.02E+08 1.02E+08 1   NM_002502 NP_002493 9989825,10094826,12380689,12020944,11491660,11291593,10978675,9143018,10485710,10485711,12470896,10894547,12150997,15176485,12391591,10754263,11493922,12424381,16183991,18599449,22706308,19135889,22302838,23159929,23019125,16723383,23636330,23521863,15685170,15685173,9011632,12529332 Nfkb2;Mus musculus,Rel;Drosophila melanogaster,Nfkb2;Rattus norvegicus,nfkb2;Danio rerio
21 STAT5B   signal transducer and activator of transcription 5B 6777 STA5B_HUMAN downstream 17q11.2 42199177 42276406 -1   NM_012448 NP_036580 ####### Stat5b;Mus musculus,Stat5b;Rattus norvegicus,Stat92E;Drosophila melanogaster,sta-1;Caenorhabditis elegans,stat5a;Danio rerio,stat5b;Danio rerio
22 STAT3 APRF signal transducer and activator of transcription 3 (acute-phase response factor) 6774 STAT3_HUMAN downstream 17q21.31 42313325 42388495 -1   NM_003150 NP_003141 ####### Stat3;Mus musculus,Stat3;Rattus norvegicus,stat3;Danio rerio,Stat92E;Drosophila melanogaster,sta-1;Caenorhabditis elegans
23 STAT5A MGF STAT5 signal transducer and activator of transcription 5A 6776 STA5A_HUMAN downstream 17q11.2 42287547 42311942 1   NM_003152 NP_003143 ####### Stat5a;Mus musculus,Stat5a;Rattus norvegicus,Stat92E;Drosophila melanogaster,sta-1;Caenorhabditis elegans,stat5a;Danio rerio,stat5b;Danio rerio
24 NRG1 HRG NDF GGF HGL NRG1-IT2 neuregulin 1 3084 NRG1_HUMAN putative 8p12 32646732 32743252 1   NM_013959 NP_039253 ####### vn;Drosophila melanogaster,Nrg1;Rattus norvegicus,Nrg1;Mus musculus,nrg1;Danio rerio
25 HDAC3 RPD3 HD3 RPD3-2 histone deacetylase 3 8841 HDAC3_HUMAN functional 5q31 1.42E+08 1.42E+08 -1   NM_003883 NP_003874 ####### Hdac3;Rattus norvegicus,Hdac3;Mus musculus,Hdac3;Drosophila melanogaster,hdac3;Danio rerio,RPD3;Saccharomyces cerevisiae
26 GH1 GH-N GHN GH hGH-N growth hormone 1 2688 SOMA_HUMAN mammal,functional,downstream 17q24.2 63917193 63918852 -1 HS_GH1 NM_000515 NP_000506 11487592,12915652,11994335,8944679,14647066,14659590,14583653,2355952,12692087,12630074,12610294,12471175,12393957,12057928,12044358,11983714,10905380,12955026,11855684,12663691,15295107,11133160,15308771,14751587,14871929,15036422,15342923,8612101,15536017,15339240,15664625,15790724,15718052,15699523,15919742,15771611,8670892,10522985,15596027,15621211,15708445,15963853,9180082,16024298,16129095,15985475,15956085,16524678,10654626,11283314,10084571,8350664,16682650,16760634,17183314,17173483,11742825,9630227,17326724,12011468,9045866,15579798,15464751,18434714,16799137,23940366,26990883,27605408,27688483,26268661 Gh;Mus musculus,Gh1;Rattus norvegicus,gh1;Danio rerio
27 IL7R CD127 interleukin 7 receptor 3575 IL7RA_HUMAN putative 5p13 35856875 35879603 1   NM_002185 NP_002176 ####### Il7r;Mus musculus,Il7r;Rattus norvegicus,il7r;Danio rerio
28 IGF1 IGF1A IGFI IGF-I insulin-like growth factor 1 (somatomedin C) 3479 IGF1B_HUMAN functional 12q23.2 1.02E+08 1.02E+08 -1   NM_000618 NP_000609 12933651,10875265,12169020,12843179,10873623,11213270,8402902,12692087,12652183,12630074,12610294,12393957,12057928,12044358,12014835,11983714,14645858,14602984,14580857,12900169,12882326,12882324,12845331,12714272,11381260,10385438,11855684,12865482,12663691,12750521,11175789,8402901,9861016,9593409,15295107,11133160,15308771,14871929,15247062,14745968,15190176,15036422,15342923,14726476,8612101,15192154,15621205,15536017,15339240,15456908,15664625,10022403,15790724,12559758,15205477,15888324,15718052,15919742,15637588,15771611,15820683,15708981,15596027,15621211,16123266,9180082,16024298,16123158,16164423,16129095,15985475,15956085,16269543,16288288,16439206,11172010,16524678,16293644,16298247,16170353,16631584,16682650,16631585,16760634,16890541,16505167,16652371,18054318,17183314,17173483,9630227,11586954,17973971,18316725,10752709,17373631,17326724,21799924,19896963,3197646,19103645,19619420,20351075,18762812,12049864,7664676,20946987,16625210,22021391,9045866,10077613,9353126,11106682,15621218,15579798,15956778,18434714,22733568,11213276,15288688,15272020,20610588,23873963,24341939,25369265,17301034,25244225,24618355 Igf1;Mus musculus,Igf1;Rattus norvegicus,igf1;Danio rerio
29 IGF2 FLJ44734 IGF-II C11orf43 insulin-like growth factor 2 3481 IGF2_HUMAN functional 11p15.5 2129112 2138974 -1 HS_IGF2_4 NM_000612 NP_000603 ####### Igf2;Mus musculus,Igf2;Rattus norvegicus,igf2a;Danio rerio,igf2b;Danio rerio
30 INS IDDM2 IDDM1 insulin 3630 INS_HUMAN functional 11p15.5 2159778 2161209 -1 HS_INS NM_000207 NP_000198 12933651,12169020,12543978,10873623,12610294,11927387,14645858,11738155,14618027,14580857,12955025,12900169,12882326,12882324,12845331,12750520,10066179,11381260,11818964,12750521,12447443,9888854,11274053,12032158,15295107,15190176,15342923,14747284,12023258,15192154,15565107,12559758,15205477,15919793,15888324,15637588,15771611,15820683,15708981,16098828,16123266,16098826,11440717,12530968,16164423,16269543,16288288,11160162,16443777,16524678,16366736,15546000,16631584,16682650,16631585,16611697,16890541,12908874,16505167,17173483,18443001,17908559,17652964,19619420,21873205,20946987,18223156,16625210,15685173,12219087,16282554,10077613,9353126,10747954,11106682,15621218,15175753,11443193,11016890,17928362,15288688,15272020,14747283,25888600 Ins1;Mus musculus,Ins2;Mus musculus,Ins1;Rattus norvegicus,Ins2;Rattus norvegicus,ins;Danio rerio,insb;Danio rerio
31 NGF NGFB nerve growth factor (beta polypeptide) 4803 NGF_HUMAN putative 1p13.1 1.15E+08 1.15E+08 -1   NM_002506 NP_002497 ####### Ngf;Mus musculus,ngfa;Danio rerio,ngfb;Danio rerio,Ngf;Rattus norvegicus
32 IRS1 HIRS-1 insulin receptor substrate 1 3667 IRS1_HUMAN model 2q36 2.27E+08 2.27E+08 -1   NM_005544 NP_005535 ####### Irs1;Mus musculus,Irs1;Rattus norvegicus,chico;Drosophila melanogaster,irs1;Danio rerio
33 PTPN1 PTP1B protein tyrosine phosphatase, non-receptor type 1 5770 PTN1_HUMAN downstream 20q13.1-q1 50510321 50584762 1   NM_002827 NP_002818 ####### Ptpn1;Mus musculus,Ptpn1;Rattus norvegicus,ptpn1;Danio rerio,Ptp61F;Drosophila melanogaster,PTP1;Saccharomyces cerevisiae
34 IRS2   insulin receptor substrate 2 8660 IRS2_HUMAN model,putative 13q34 1.1E+08 1.1E+08 -1   NM_003749 NP_003740 ####### Irs2;Rattus norvegicus,chico;Drosophila melanogaster,Irs2;Mus musculus,irs2a;Danio rerio,irs2b;Danio rerio
35 AKT1 RAC PKB PRKBA AKT v-akt murine thymoma viral oncogene homolog 1 207 AKT1_HUMAN model,cell 14q32.32 1.05E+08 1.05E+08 -1   NM_005163 NP_005154 15767565,11154281,11884591,12719720,11277998,11381260,11544177,12237475,11257494,9005851,10485710,10485711,11607034,12039436,12044943,9716402,9020362,15295107,14871929,15383658,14985531,14726476,15780592,15860463,15888324,15718052,16123266,12530968,16186101,15930121,16288288,12110585,10364160,16170353,14713953,16631584,16675393,16914869,12908874,16505167,15843522,23935948,18223156,21157483,21474066,15084260,12782654,15492215,10051603,21901288 AKT1;Danio rerio,Akt1;Mus musculus,Akt1;Rattus norvegicus,Akt1;Drosophila melanogaster,akt-1;Caenorhabditis elegans,akt-2;Caenorhabditis elegans,YPK1;Saccharomyces cerevisiae,YPK2;Saccharomyces cerevisiae,SCH9;Saccharomyces cerevisiae
36 PIK3CB PIK3C1 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 5291 PK3CB_HUMAN model,downstream 3q22.3 1.39E+08 1.39E+08 -1   NM_006219 NP_006210 ####### LOC100910021;Rattus norvegicus,Pi3K92E;Drosophila melanogaster,Pik3cb;Mus musculus,Pik3cb;Rattus norvegicus,VPS34;Saccharomyces cerevisiae,pik3cb;Danio rerio
37 NGFR TNFRSF16 CD271 p75NTR nerve growth factor receptor 4804 TNR16_HUMAN downstream 17q21-q22 49495293 49515020 1   NM_002507 NP_002498 ####### Ngfr;Mus musculus,Ngfr;Rattus norvegicus,ngfrb;Danio rerio,ngfra;Danio rerio
38 HRAS HRAS1 Harvey rat sarcoma viral oncogene homolog 3265 RASH_HUMAN model,cell 11p15.5 532242 535550 1 HS_HRAS_3 NM_005343 NP_005334 ############################################################################################################################################################################################################################################################### Hras;Mus musculus,Ras85D;Drosophila melanogaster,let-60;Caenorhabditis elegans,Hras;Rattus norvegicus,Hras;Rattus norvegicus,hrasa;Danio rerio,hrasb;Danio rerio,RAS1;Saccharomyces cerevisiae,RAS2;Saccharomyces cerevisiae
39 MYC c-Myc bHLHe39 MYCC v-myc avian myelocytomatosis viral oncogene homolog 4609 MYC_HUMAN cell,upstream 8q24.21 1.28E+08 1.28E+08 1 HS_MYC_2 NM_002467 NP_002458 ####### Myc;Mus musculus,Myc;Rattus norvegicus,myca;Danio rerio,dm;Drosophila melanogaster,mycb;Danio rerio
40 EGFR ERBB1 ERBB epidermal growth factor receptor 1956 EGFR_HUMAN downstream 7p12 55019032 55207338 1 HS_EGFR_2 NM_005228 NP_005219 ####### Egfr;Mus musculus,Egfr;Rattus norvegicus,Egfr;Drosophila melanogaster,egfra;Danio rerio
41 ERBB2 NEU HER-2 CD340 HER2 NGL erb-b2 receptor tyrosine kinase 2 2064 ERBB2_HUMAN downstream 17q12 39699978 39728662 1 HS_ERBB2_2 NM_004448 NP_004439 ####### Erbb2;Mus musculus,Erbb2;Rattus norvegicus,Egfr;Drosophila melanogaster,erbb2;Danio rerio,LOC102552659;Rattus norvegicus
42 INSR CD220 insulin receptor 3643 INSR_HUMAN model 19p13 7112255 7294000 -1   NM_000208 NP_000199 12543978,11292875,11021802,11242085,8247153,11927387,10066179,12882356,9252323,12447443,14698816,9716402,10428762,11274053,15295107,10025399,15190176,15342923,15466429,15565107,15253933,15888324,16123266,12530968,16099946,16524678,2544998,16631585,12908874,9789046,18001293,15582274,15175753,25319083 Insr;Rattus norvegicus,Insr;Mus musculus,InR;Drosophila melanogaster,daf-2;Caenorhabditis elegans,insra;Danio rerio,insrb;Danio rerio
43 NCOR1 N-CoR hCIT529I10 TRAC1 hN-CoR KIAA1047 MGC104216 PPP1R109 nuclear receptor corepressor 1 9611 NCOR1_HUMAN downstream 17p11.2 16030094 16215560 -1   NM_006311 NP_006302 ####### Ncor1;Mus musculus,Smr;Drosophila melanogaster,Ncor1;Rattus norvegicus,gei-8;Caenorhabditis elegans,ncor1;Danio rerio,SNT1;Saccharomyces cerevisiae
44 NBN ATV AT-V2 AT-V1 NBS NBS1 nibrin 4683 NBN_HUMAN functional,putative 8q21 89933336 89984671 -1   NM_002485 NP_002476 ####### Nbn;Mus musculus,nbs;Drosophila melanogaster,Nbn;Rattus norvegicus,nbn;Danio rerio
45 JUND AP-1 jun D proto-oncogene 3727 JUND_HUMAN mammal,putative 19p13.2 18279694 18281656 -1   NM_005354 NP_005345 ####### Jund;Mus musculus,Jund;Rattus norvegicus,Jra;Drosophila melanogaster,jund;Danio rerio
46 IL2 IL-2 TCGF interleukin 2 3558 IL2_HUMAN putative 4q26-q27 1.22E+08 1.22E+08 -1 HS_IL2 NM_000586 NP_000577 ####### Il2;Mus musculus,Il2;Rattus norvegicus
47 PDGFB SSV SIS platelet-derived growth factor beta polypeptide 5155 PDGFB_HUMAN upstream 22q13.1 39223680 39244952 -1 HS_PDGFB NM_002608 NP_002599 ####### Pdgfb;Mus musculus,Pdgfb;Rattus norvegicus,pdgfbb;Danio rerio,pdgfba;Danio rerio
48 EGF   epidermal growth factor 1950 EGF_HUMAN upstream 4q25 1.1E+08 1.1E+08 1   NM_001963 NP_001954 ####### LOC103691699;Rattus norvegicus,Egf;Mus musculus,cue;Drosophila melanogaster,egf;Danio rerio,Egf;Rattus norvegicus
49 IL2RG CD132 SCIDX1 IMD4 CIDX interleukin 2 receptor, gamma 3561 IL2RG_HUMAN downstream Xq13.1 71107406 71111631 -1 HS_IL2RG NM_000206 NP_000197 ####### Gm20489;Mus musculus,Il2rg;Mus musculus,Il2rg;Rattus norvegicus,il2rga;Danio rerio,il2rgb;Danio rerio
50 FOS c-fos AP-1 FBJ murine osteosarcoma viral oncogene homolog 2353 FOS_HUMAN putative 14q24.3 75278778 75282234 1 HS_FOS NM_005252 NP_005243 ####### Fos;Mus musculus,Fos;Rattus norvegicus,FOS (1 of many);Danio rerio,fosaa;Danio rerio,kay;Drosophila melanogaster
51 PDGFRB JTK12 CD140b PDGFR1 PDGFR platelet-derived growth factor receptor, beta polypeptide 5159 PGFRB_HUMAN downstream 5q33.1 1.5E+08 1.5E+08 -1   NM_002609 NP_002600 ####### PDGFRB;Danio rerio,Pdgfrb;Mus musculus,Pdgfrb;Rattus norvegicus,Pvr;Drosophila melanogaster
52 EPOR EPO-R Erythropoietin receptor 2057 EPOR_HUMAN downstream 19p13.2 11377204 11384341 -1   NM_000121 NP_000112 ####### Epor;Mus musculus,Epor;Rattus norvegicus,epor;Danio rerio
53 SST SMST somatostatin 6750 SMS_HUMAN upstream 3q28 1.88E+08 1.88E+08 -1 HS_SST NM_001048 NP_001039 ####### Sst;Mus musculus,Sst;Rattus norvegicus,sst1.1;Danio rerio
54 PRKCD   protein kinase C, delta 5580 KPCD_HUMAN downstream 3p21.31 53161207 53192717 1   NM_006254 NP_006245 ####### pck1;Schizosaccharomyces pombe,Prkcd;Mus musculus,Pkcdelta;Drosophila melanogaster,Prkcd;Rattus norvegicus,tpa-1;Caenorhabditis elegans,prkcda;Danio rerio,PKC1;Saccharomyces cerevisiae,prkcdb;Danio rerio
55 PPARA hPPAR NR1C1 PPAR peroxisome proliferator-activated receptor alpha 5465 PPARA_HUMAN putative 22q13.31 46150596 46243756 1   NM_005036 NP_005027 ####### Ppara;Mus musculus,Ppara;Rattus norvegicus,sex-1;Caenorhabditis elegans,nhr-38;Caenorhabditis elegans,pparab;Danio rerio,pparaa;Danio rerio
56 RET PTC CDHF12 RET51 CDHR16 HSCR1 MEN2A MTC1 MEN2B ret proto-oncogene 5979 RET_HUMAN downstream 10q11.2 43077069 43130349 1   NM_020975 NP_066124 ####### Ret;Mus musculus,Ret;Rattus norvegicus,ret;Danio rerio,Ret;Drosophila melanogaster
57 PLCG2   phospholipase C, gamma 2 (phosphatidylinositol-specific) 5336 PLCG2_HUMAN downstream 16q24.1 81779258 81962693 1   NM_002661 NP_002652 ####### si:ch211-260p9.3;Danio rerio,Plcg2;Rattus norvegicus,sl;Drosophila melanogaster,plc-3;Caenorhabditis elegans,Plcg2;Mus musculus,plcg2;Danio rerio,PLC1;Saccharomyces cerevisiae
58 PEX5 PTS1R PXR1 peroxisomal biogenesis factor 5 5830 PEX5_HUMAN functional 12p13.31 7190362 7211483 1   NM_000319 NP_000310 ####### LOC103690024;Rattus norvegicus,Pex5;Mus musculus,Pex5;Drosophila melanogaster,prx-5;Caenorhabditis elegans,Pex5;Rattus norvegicus,pex5;Danio rerio,PEX5;Saccharomyces cerevisiae
59 TCF3 E2A ITF1 MGC129647 MGC129648 bHLHb21 VDIR E47 transcription factor 3 6929 TFE2_HUMAN putative 19p13.3 1609290 1652329 -1   NM_003200 NP_003191 ####### Tcf3;Mus musculus,tcf3a;Danio rerio,da;Drosophila melanogaster,Tcf3;Rattus norvegicus,hlh-2;Caenorhabditis elegans,tcf3b;Danio rerio
60 PARP1 PARP PPOL ADPRT poly (ADP-ribose) polymerase 1 142 PARP1_HUMAN functional,putative 1q41-q42 2.26E+08 2.26E+08 -1 HS_ADPRT NM_001618 NP_001609 1465394,10471503,14612404,12470832,11906946,11707919,11121685,11016956,9587069,10077636,12543974,12114629,2559326,14734561,15044383,12526788,15292449,12605957,15336909,15545322,17913748,15590998,15205477,16141234,15895395,16140981,16107709,16302026,16207712,16628003,20832105,21680843,19139632,20231360,3103132,9312059,22753495,18835851,15855340,9325154,24843141,26598704 Parp1;Mus musculus,Parp1;Rattus norvegicus,parp-1;Caenorhabditis elegans,parp1;Danio rerio,Parp;Drosophila melanogaster
61 BRCA1 RNF53 BRCC1 PPP1R53 FANCS breast cancer 1, early onset 672 BRCA1_HUMAN mammal 17q21 43044295 43125483 -1   NM_007294 NP_009225 ############################################################################################################################################################################################################################################################### Brca1;Mus musculus,Brca1;Rattus norvegicus
62 PIN1 dod peptidylprolyl cis/trans isomerase, NIMA-interacting 1 5300 PIN1_HUMAN upstream 19p13 9835207 9849689 1 HS_PIN1 NM_006221 NP_006212 ####### pin1;Schizosaccharomyces pombe,pin1;Danio rerio,Pin1;Mus musculus,dod;Drosophila melanogaster,pinn-1;Caenorhabditis elegans,Pin1rt1;Mus musculus,Pin1;Rattus norvegicus,CG32845;Drosophila melanogaster,ESS1;Saccharomyces cerevisiae
63 PTEN MMAC1 TEP1 PTEN1 BZS MHAM phosphatase and tensin homolog 5728 PTEN_HUMAN model 10q23.3 87863438 87971930 1   NM_000314 NP_000305 ####### Pten;Mus musculus,Pten;Drosophila melanogaster,Pten;Rattus norvegicus,daf-18;Caenorhabditis elegans,ptenb;Danio rerio
64 CREBBP RTS CBP KAT3A RSTS CREB binding protein 1387 CBP_HUMAN upstream 16p13.3 3725055 3880120 -1   NM_004380 NP_004371 ####### Crebbp;Mus musculus,nej;Drosophila melanogaster,Crebbp;Rattus norvegicus,cbp-1;Caenorhabditis elegans,F40F12.7;Caenorhabditis elegans,cbp-2;Caenorhabditis elegans,crebbpa;Danio rerio,crebbpb;Danio rerio,BDF1;Saccharomyces cerevisiae,BDF2;Saccharomyces cerevisiae
65 HIF1A MOP1 HIF-1alpha PASD8 HIF1 bHLHe78 hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 3091 HIF1A_HUMAN functional,downstream 14q23.2 61695401 61748259 1 HS_HIF1A NM_001530 NP_001521 ####### Hif1a;Mus musculus,Hif1a;Rattus norvegicus,sima;Drosophila melanogaster,hif-1;Caenorhabditis elegans,hif1ab;Danio rerio,hif1aa;Danio rerio
66 UBB MGC8385 FLJ25987 ubiquitin B 7314 UBIQ_HUMAN putative 17p12-p11. 16380797 16382745 1 HS_UBB NM_018955 NP_061828 ####### ubq-1;Caenorhabditis elegans,UBI4;Saccharomyces cerevisiae
67 RPA1 REPA1 RPA70 HSSB RF-A RP-A replication protein A1, 70kDa 6117 RFA1_HUMAN upstream 17p13.3 1829979 1899554 1   NM_002945 NP_002936 ####### ssb1;Schizosaccharomyces pombe,RpA-70;Drosophila melanogaster,Rpa1;Mus musculus,rpa-1;Caenorhabditis elegans,Rpa1;Rattus norvegicus,rpa1;Danio rerio,RFA1;Saccharomyces cerevisiae
68 BLM BS RECQL3 RECQ2 Bloom syndrome, RecQ helicase-like 641 BLM_HUMAN functional 15q26.1 90717326 90815462 1   NM_000057 NP_000048 ####### rqh1;Schizosaccharomyces pombe,Blm;Mus musculus,Blm;Drosophila melanogaster,him-6;Caenorhabditis elegans,Blm;Rattus norvegicus,blm;Danio rerio,SGS1;Saccharomyces cerevisiae
69 BCL2 Bcl-2 PPP1R50 B-cell CLL/lymphoma 2 596 BCL2_HUMAN functional 18q21.3 63123346 63319380 -1 HS_BCL2_2 NM_000633 NP_000624 9989825,12462383,9315450,8090743,8170972,8692941,11226431,9102310,8358790,9228005,12161751,9288026,15013668,15295107,12218115,8235659,15489059,15618488,15897889,16139996,16198025,16367931,16567372,7946326,16288037,17973971,10656180,22343142,16026332,15911345,7472523 Bcl2;Mus musculus,Bcl2;Rattus norvegicus,bcl2a;Danio rerio,bcl2b;Danio rerio
70 S100B S100beta S100 calcium binding protein B 6285 S100B_HUMAN upstream,putative 21q22.3 46598618 46605122 -1 HS_S100B NM_006272 NP_006263 ####### S100b;Mus musculus,S100b;Rattus norvegicus,s100b;Danio rerio
71 VCP IBMPFD p97 valosin containing protein 7415 TERA_HUMAN downstream 9p13.3 35056068 35072742 -1 HS_VCP_2 NM_007126 NP_009057 ####### cdc48;Schizosaccharomyces pombe,TER94;Drosophila melanogaster,Vcp;Rattus norvegicus,cdc-48.2;Caenorhabditis elegans,cdc-48.1;Caenorhabditis elegans,Vcp;Mus musculus,vcp;Danio rerio,CDC48;Saccharomyces cerevisiae
72 POLG POLG1 POLGA polymerase (DNA directed), gamma 5428 DPOG1_HUMAN mammal 15q25 89316305 89334795 -1   NM_002693 NP_002684 ####### Polg;Mus musculus,tam;Drosophila melanogaster,Polg;Rattus norvegicus,polg-1;Caenorhabditis elegans,MIP1;Saccharomyces cerevisiae,polg;Danio rerio
73 IGFBP3 IBP3 BP-53 insulin-like growth factor binding protein 3 3486 IBP3_HUMAN upstream 7p13-p12 45912245 45921272 -1 HS_IGFBP3 NM_000598 NP_000589 ####### Igfbp3;Mus musculus,Igfbp3;Rattus norvegicus,igfbp3;Danio rerio
74 HSP90AA1 Hsp89 Hsp90 FLJ31884 HSP90N HSPC1 HSPCA heat shock protein 90kDa alpha (cytosolic), class A member 1 3320 HS90A_HUMAN functional 14q32.33 1.02E+08 1.02E+08 -1 HS_HSPCA NM_005348 NP_005339 ####### Hsp90aa1;Mus musculus,hsp90aa1.1;Danio rerio,Hsp83;Drosophila melanogaster,daf-21;Caenorhabditis elegans,LOC103692716;Rattus norvegicus,hsp90aa1.2;Danio rerio,HSC82;Saccharomyces cerevisiae,HSP82;Saccharomyces cerevisiae,Hsp90aa1;Rattus norvegicus
75 NR3C1 GR GRL nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 2908 GCR_HUMAN downstream 5q31.3 1.43E+08 1.43E+08 -1   NM_000176 NP_000167 ####### Nr3c1;Rattus norvegicus,Nr3c1;Mus musculus,nr3c1;Danio rerio
76 EGR1 TIS8 G0S30 NGFI-A KROX-24 ZIF-268 AT225 ZNF225 early growth response 1 1958 EGR1_HUMAN upstream 5q31.1 1.38E+08 1.38E+08 1   NM_001964 NP_001955 ####### prz1;Schizosaccharomyces pombe,Egr1;Mus musculus,Egr1;Rattus norvegicus,egr1;Danio rerio,sr;Drosophila melanogaster,egrh-1;Caenorhabditis elegans,egrh-2;Caenorhabditis elegans,MIG2;Saccharomyces cerevisiae,MIG1;Saccharomyces cerevisiae,MIG3;Saccharomyces cerevisiae
77 VEGFA VEGF-A VPF VEGF vascular endothelial growth factor A 7422 VEGFA_HUMAN putative 6p12 43770209 43786486 1   NM_003376 NP_003367 ####### Vegfa;Mus musculus,vegfaa;Danio rerio,Vegfa;Rattus norvegicus,vegfab;Danio rerio
78 ABL1 JTK7 c-ABL p150 ABL ABL proto-oncogene 1, non-receptor tyrosine kinase 25 ABL1_HUMAN functional,downstream 9q34.1 1.31E+08 1.31E+08 1 HS_ABL1_3 NM_007313 NP_009297 ####### Abl1;Mus musculus,Abl;Drosophila melanogaster,abl-1;Caenorhabditis elegans,Abl1;Rattus norvegicus,abl1;Danio rerio,Abl1;Rattus norvegicus,Abl1;Rattus norvegicus
79 BRCA2 FAD FAD1 BRCC2 XRCC11 FANCD1 FACD FANCD breast cancer 2, early onset 675 BRCA2_HUMAN functional 13q12.3 32315480 32399672 1   NM_000059 NP_000050 ####### Brca2;Mus musculus,Brca2;Rattus norvegicus,brca2;Danio rerio
80 TOP2A TOP2 topoisomerase (DNA) II alpha 7153 TOP2A_HUMAN functional 17q21-q22 40388521 40417950 -1   NM_001067 NP_001058 ####### Top2a;Rattus norvegicus,Top2a;Mus musculus,Top2;Drosophila melanogaster,top-2;Caenorhabditis elegans,cin-4;Caenorhabditis elegans,top2a;Danio rerio,TOP2;Saccharomyces cerevisiae
81 TOP2B   topoisomerase (DNA) II beta 7155 TOP2B_HUMAN functional 3p24 25597905 25664372 -1   NM_001068 NP_001059 ####### top2;Schizosaccharomyces pombe,Top2b;Mus musculus,Top2;Drosophila melanogaster,top-2;Caenorhabditis elegans,cin-4;Caenorhabditis elegans,top2b;Danio rerio,TOP2;Saccharomyces cerevisiae
82 NFKB1 KBF1 p105 NFKB-p50 p50 NF-kappaB NFkappaB NF-kB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 4790 NFKB1_HUMAN functional 4q24 1.03E+08 1.03E+08 1   NM_003998 NP_003989 9989825,12380689,12020944,11491660,11291593,10978675,9143018,10485710,10485711,11931769,12470896,7834752,14561702,10894547,12150997,12391591,10754263,11493922,12424381,16183991,18599449,22706308,19135889,22302838,18362329,23159929,23019125,16723383,23636330,23521863,15685170,15685173,9011632,12529332,24960204,25553648 Nfkb1;Mus musculus,Rel;Drosophila melanogaster,Nfkb1;Rattus norvegicus,nfkb1;Danio rerio
83 TOP1   topoisomerase (DNA) I 7150 TOP1_HUMAN functional 20q12-q13. 41028822 41124486 1   NM_003286 NP_003277 ####### top1mt;Danio rerio,Top1;Mus musculus,Top1;Drosophila melanogaster,Top1;Rattus norvegicus,top-1;Caenorhabditis elegans,Top1;Rattus norvegicus,TOP1;Saccharomyces cerevisiae
84 RAD51 HsRad51 HsT16930 BRCC5 FANCR RAD51A RECA RAD51 recombinase 5888 RAD51_HUMAN cell,functional 15q15.1 40695129 40732158 1 HS_RAD51 NM_002875 NP_002866 ####### rhp51;Schizosaccharomyces pombe,Rad51;Mus musculus,spn-A;Drosophila melanogaster,rad51;Danio rerio,Rad51;Rattus norvegicus,RAD51;Saccharomyces cerevisiae
85 UBE2I UBC9 ubiquitin-conjugating enzyme E2I 7329 UBC9_HUMAN upstream 16p13.3 1309627 1327018 1   NM_194259 NP_919235 ####### hus5;Schizosaccharomyces pombe,LOC102553386;Rattus norvegicus,Ube2i;Mus musculus,Ube2i;Rattus norvegicus,lwr;Drosophila melanogaster,ube2ia;Danio rerio,UBC9;Saccharomyces cerevisiae,ubc-9;Caenorhabditis elegans
86 TNF TNFSF2 DIF TNF-alpha TNFA tumor necrosis factor 7124 TNFA_HUMAN putative 6p21.3 2917465 2920233 1 HS_TNF NM_000594 NP_000585 ############################################################################################################################################################################################################################################################### Tnf;Mus musculus,Tnf;Rattus norvegicus,tnfa;Danio rerio,tnfb;Danio rerio,LOC103694380;Rattus norvegicus
87 PDPK1 PDK1 3-phosphoinositide dependent protein kinase 1 5170 PDPK1_HUMAN downstream 16p13.3 2537964 2603190 1   NM_002613 NP_002604 ####### Pdpk1;Mus musculus,Pdk1;Drosophila melanogaster,Pdpk1;Rattus norvegicus,pdk-1;Caenorhabditis elegans,pdpk1b;Danio rerio,pdpk1a;Danio rerio,PKH3;Saccharomyces cerevisiae,PKH1;Saccharomyces cerevisiae,PKH2;Saccharomyces cerevisiae
88 CEBPA C/EBP-alpha CEBP CCAAT/enhancer binding protein (C/EBP), alpha 1050 CEBPA_HUMAN functional 19q13.1 33299934 33302564 -1   NM_004364 NP_004355 ####### Cebpa;Mus musculus,Cebpa;Rattus norvegicus,cebpa;Danio rerio,cebp-2;Caenorhabditis elegans
89 CEBPB LAP CRP2 NFIL6 IL6DBP C/EBP-beta TCF5 CCAAT/enhancer binding protein (C/EBP), beta 1051 CEBPB_HUMAN mammal 20q13.1 50190583 50192691 1   NM_005194 NP_005185 ####### Cebpb;Mus musculus,Cebpb;Rattus norvegicus,cebpb;Danio rerio,cebp-2;Caenorhabditis elegans
90 MXI1 MXD2 MAD2 MXI bHLHc11 MAX interactor 1, dimerization protein 4601 MXI1_HUMAN putative 10q24-q25 1.1E+08 1.1E+08 1   NM_005962 NP_005953 ####### Mxi1;Mus musculus,Mxi1;Rattus norvegicus,mxi1;Danio rerio,mdl-1;Caenorhabditis elegans
91 TGFB1 CED TGFbeta TGFB DPD1 transforming growth factor, beta 1 7040 TGFB1_HUMAN putative 19q13.1 41330531 41353933 -1   NM_000660 NP_000651 ############################################################################################################################################################################################################################################################### Tgfb1;Mus musculus,daw;Drosophila melanogaster,Tgfb1;Rattus norvegicus,tgfb1a;Danio rerio,tgfb1b;Danio rerio
92 ERCC6 CSB RAD26 ARMD5 CKN2 excision repair cross-complementation group 6 2074 ERCC6_HUMAN functional 10q11.23 49454480 49539123 -1   NM_000124 NP_000115 ####### rhp26;Schizosaccharomyces pombe,Ercc6;Rattus norvegicus,Ercc6;Mus musculus,ercc6;Danio rerio,RAD26;Saccharomyces cerevisiae
93 STK11 PJS LKB1 serine/threonine kinase 11 6794 STK11_HUMAN upstream 19p13.3 1205799 1228435 1   NM_000455 NP_000446 ####### Stk11;Mus musculus,lkb1;Drosophila melanogaster,par-4;Caenorhabditis elegans,Stk11;Rattus norvegicus,stk11;Danio rerio,TOS3;Saccharomyces cerevisiae,SAK1;Saccharomyces cerevisiae
94 EP300 p300 KAT3B E1A binding protein p300 2033 EP300_HUMAN upstream 22q13.2 41092610 41180077 1   NM_001429 NP_001420 ####### Ep300;Rattus norvegicus,nej;Drosophila melanogaster,cbp-1;Caenorhabditis elegans,F40F12.7;Caenorhabditis elegans,cbp-2;Caenorhabditis elegans,Ep300;Mus musculus,BDF1;Saccharomyces cerevisiae,BDF2;Saccharomyces cerevisiae
95 APTX FLJ20157 AOA AOA1 EAOH EOAHA AXA1 aprataxin 54840 APTX_HUMAN functional 9p13.3 32972606 33001641 -1   NM_175073 NP_778243 ####### hnt3;Schizosaccharomyces pombe,CG5316;Drosophila melanogaster,Aptx;Mus musculus,Aptx;Rattus norvegicus,aptx;Danio rerio,HNT3;Saccharomyces cerevisiae
96 PML MYL TRIM19 RNF71 promyelocytic leukemia 5371 PML_HUMAN cell,downstream 15q22 73994673 74047814 1   NM_033238 NP_150241 ####### Pml;Mus musculus,Pml;Rattus norvegicus
97 GSK3B   glycogen synthase kinase 3 beta 2932 GSK3B_HUMAN downstream 3q13.3 1.2E+08 1.2E+08 -1   NM_002093 NP_002084 ####### gsk3b;Danio rerio,sgg;Drosophila melanogaster,Gsk3b;Mus musculus,Gsk3b;Rattus norvegicus,gsk-3;Caenorhabditis elegans,GSK3B (1 of many);Danio rerio,MRK1;Saccharomyces cerevisiae,RIM11;Saccharomyces cerevisiae
98 HTT IT15 HD huntingtin 3064 HD_HUMAN mammal 4p16.3 3074510 3243960 1   NM_002111 NP_002102 ####### Htt;Mus musculus,Htt;Rattus norvegicus,htt;Danio rerio,htt;Drosophila melanogaster
99 PRKCA PKCA protein kinase C, alpha 5578 KPCA_HUMAN downstream 17q22-q23. 66302808 66810744 1   NM_002737 NP_002728 ####### Prkca;Mus musculus,Prkca;Rattus norvegicus,inaC;Drosophila melanogaster,Pkc53E;Drosophila melanogaster,pkc-2;Caenorhabditis elegans,prkca;Danio rerio,PKC1;Saccharomyces cerevisiae,PRKCA (1 of many);Danio rerio
100 SSTR3   somatostatin receptor 3 6753 SSR3_HUMAN downstream 22q13.1 37204237 37212376 -1   NM_001051 NP_001042 ####### Sstr3;Mus musculus,AstC-R2;Drosophila melanogaster,AstC-R1;Drosophila melanogaster,Sstr3;Rattus norvegicus,npr-24;Caenorhabditis elegans,sstr3;Danio rerio,SSTR3 (1 of many);Danio rerio
101 HELLS PASG SMARCA6 LSH Nbla10143 helicase, lymphoid-specific 3070 HELLS_HUMAN mammal 10q24.2 94545767 94602099 1   NM_018063 NP_060533 ####### Hells;Mus musculus,Hells;Rattus norvegicus,LOC100911660;Rattus norvegicus,hells;Danio rerio,IRC5;Saccharomyces cerevisiae,Hells;Rattus norvegicus,LOC100911660;Rattus norvegicus
102 APOC3   apolipoprotein C-III 345 APOC3_HUMAN putative 11q23.3 1.17E+08 1.17E+08 1 HS_APOC3 NM_000040 NP_000031 ####### Apoc3;Mus musculus,Apoc3;Rattus norvegicus
103 EEF2 EEF-2 EF2 eukaryotic translation elongation factor 2 1938 EF2_HUMAN putative 19p13.3 3976056 3985463 -1   NM_001961 NP_001952 ####### eft201;Schizosaccharomyces pombe,Eef2;Mus musculus,Eef2;Rattus norvegicus,EF2;Drosophila melanogaster,eef-2;Caenorhabditis elegans,eef2l2;Danio rerio,EFT1;Saccharomyces cerevisiae,EFT1;Saccharomyces cerevisiae
104 ERCC3 XPB BTF2 RAD25 TFIIH GTF2H excision repair cross-complementation group 3 2071 ERCC3_HUMAN functional 2q21 1.27E+08 1.27E+08 -1 HS_ERCC3 NM_000122 NP_000113 ####### ercc3;Schizosaccharomyces pombe,Ercc3;Mus musculus,hay;Drosophila melanogaster,xpb-1;Caenorhabditis elegans,Ercc3;Rattus norvegicus,ercc3;Danio rerio,SSL2;Saccharomyces cerevisiae
105 TERF1 PIN2 TRF1 TRF TRBF1 telomeric repeat binding factor (NIMA-interacting) 1 7013 TERF1_HUMAN functional 8q21.11 73008862 73047752 1   NM_017489 NP_059523 ####### Terf1;Mus musculus,Terf1;Rattus norvegicus,terf1;Danio rerio
106 PRKDC DNPK1 p350 DNAPK XRCC7 DNA-PKcs HYRC HYRC1 protein kinase, DNA-activated, catalytic polypeptide 5591 PRKDC_HUMAN functional 8q11 47773108 47960183 -1   NM_006904 NP_008835 ####### Prkdc;Mus musculus,atl-1;Caenorhabditis elegans,Prkdc;Rattus norvegicus,prkdc;Danio rerio,MEC1;Saccharomyces cerevisiae
107 CAT   catalase 847 CATA_HUMAN model 11p13 34438925 34472060 1   NM_001752 NP_001743 8108730,12743125,11033419,10968795,11117918,12815103,12792161,12521602,10767579,2268310,2308162,1999334,11382788,10567403,15295107,15308771,11479740,8655605,15879174,16129095,16288288,16260109,16298100,16298747,16518719,16563232,16581216,14996832,16213688,15954861,17446436,17201740,21109199,18772469,23277187,16723383,15101064,15059885,19652361,11182520,25288763,27575890 cta1;Schizosaccharomyces pombe,Cat;Mus musculus,Cat;Rattus norvegicus,cat;Danio rerio,CG9314;Drosophila melanogaster,Cat;Drosophila melanogaster,ctl-2;Caenorhabditis elegans,ctl-3;Caenorhabditis elegans,ctl-1;Caenorhabditis elegans,CTA1;Saccharomyces cerevisiae
109 ERCC5 ERCM2 XPGC excision repair cross-complementation group 5 2073 ERCC5_HUMAN functional 13q33 1.03E+08 1.03E+08 1   NM_000123 NP_000114 ####### rad13;Schizosaccharomyces pombe,Ercc5;Rattus norvegicus,Ercc5;Mus musculus,gen-1;Caenorhabditis elegans,xpg-1;Caenorhabditis elegans,ercc5;Danio rerio,RAD2;Saccharomyces cerevisiae,mus201;Drosophila melanogaster
110 AR AIS NR3C4 SMAX1 HUMARA DHTR SBMA androgen receptor 367 ANDR_HUMAN upstream Xq12 67544032 67730619 1   NM_000044 NP_000035 ####### Ar;Mus musculus,Ar;Rattus norvegicus,ar;Danio rerio
111 GTF2H2 BTF2 TFIIH BTF2P44 T-BTF2P44 p44 general transcription factor IIH, polypeptide 2, 44kDa 2966 TF2H2_HUMAN downstream 5q13.2 70415374 70447906 1   NM_001515 NP_001506 ####### Gtf2h2;Mus musculus,Ssl1;Drosophila melanogaster,T16H12.4;Caenorhabditis elegans,Gtf2h2;Rattus norvegicus,gtf2h2;Danio rerio,SSL1;Saccharomyces cerevisiae
112 XRCC5 KU80 KARP-1 Ku86 KUB2 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 7520 KU86_HUMAN mammal 2q35 2.16E+08 2.16E+08 1   NM_021141 NP_066964 ############################################################################################################################################################################################################################################################### pku80;Schizosaccharomyces pombe,Xrcc5;Mus musculus,Ku80;Drosophila melanogaster,Xrcc5;Rattus norvegicus,xrcc5;Danio rerio
113 PCNA   proliferating cell nuclear antigen 5111 PCNA_HUMAN functional 20pter-p12 5114953 5120001 -1   NM_182649 NP_872590 ####### pcn1;Schizosaccharomyces pombe,Pcna-ps2;Mus musculus,Pcna;Mus musculus,Pcna;Rattus norvegicus,pcna;Danio rerio,CG10262;Drosophila melanogaster,PCNA;Drosophila melanogaster,pcn-1;Caenorhabditis elegans,POL30;Saccharomyces cerevisiae
114 FEN1 FEN-1 MF1 RAD2 flap structure-specific endonuclease 1 2237 FEN1_HUMAN downstream 11q12 61792637 61797242 1 HS_FEN1 NM_004111 NP_004102 ####### rad2;Schizosaccharomyces pombe,Fen1;Mus musculus,Fen1;Rattus norvegicus,crn-1;Caenorhabditis elegans,fen1;Danio rerio,RAD27;Saccharomyces cerevisiae
115 FAS CD95 APO-1 FAS1 APT1 TNFRSF6 Fas cell surface death receptor 355 TNR6_HUMAN putative 10q24.1 88990531 89015785 1   NM_000043 NP_000034 ############################################################################################################################################################################################################################################################### Fas;Mus musculus,Fas;Rattus norvegicus,fas;Danio rerio
116 TERF2 TRF2 TRBF2 telomeric repeat binding factor 2 7014 TERF2_HUMAN functional 16q22.1 69355561 69385988 -1   NM_005652 NP_005643 ####### Terf2;Mus musculus,terfa;Danio rerio,Terf2;Rattus norvegicus
117 XRCC6 D22S731 D22S671 KU70 ML8 G22P1 X-ray repair complementing defective repair in Chinese hamster cells 6 2547 KU70_HUMAN functional 22q13.2 41621163 41664048 1 HS_G22P1 NM_001469 NP_001460 ####### pku70;Schizosaccharomyces pombe,Xrcc6;Mus musculus,Xrcc6;Rattus norvegicus,Irbp;Drosophila melanogaster,cku-70;Caenorhabditis elegans,xrcc6;Danio rerio,YKU70;Saccharomyces cerevisiae
118 POLD1 CDC2 POLD polymerase (DNA directed), delta 1, catalytic subunit 5424 DPOD1_HUMAN downstream 19q13.3 50384323 50418018 1   NM_002691 NP_002682 ####### pol3;Schizosaccharomyces pombe,Pold1;Mus musculus,DNApol-delta;Drosophila melanogaster,Pold1;Rattus norvegicus,F10C2.4;Caenorhabditis elegans,pold1;Danio rerio,POL3;Saccharomyces cerevisiae
119 BAX BCL2L4 BCL2-associated X protein 581 BAX_HUMAN downstream,putative 19q13.3-q1 48954860 48961262 1   NM_004324 NP_004315 ####### BX511080.1;Danio rerio,Bax;Mus musculus,Bax;Rattus norvegicus,baxa;Danio rerio,baxb;Danio rerio,baxa;Danio rerio
120 RB1 RB PPP1R130 OSRC retinoblastoma 1 5925 RB_HUMAN cell 13q14.2 48303747 48481890 1   NM_000321 NP_000312 6320372,2673543,2673546,3162593,8885230,1321348,12581156,10557106,8278403,1641004,8119953,9537419,9353177,10950866,1689463,1406932,12379853,1830372,1655277,2895499,3823889,9491888,1881452,7736585,12607001,10199402,12757710,9468140,10958660,1710781,2594029,15688064,12486224,12882406,12530968,15716376,11035041,16481476,16892051,17664422,2673542,9219514,2163767,1901652,10594030,18800172 Rb1;Mus musculus,Rb1;Rattus norvegicus,Rbf;Drosophila melanogaster,Rbf2;Drosophila melanogaster,lin-35;Caenorhabditis elegans,rb1;Danio rerio
121 EMD STA LEMD5 emerin 2010 EMD_HUMAN functional Xq28 1.54E+08 1.54E+08 1 HS_EMD NM_000117 NP_000108 ####### Emd;Mus musculus,Emd;Rattus norvegicus
122 GRB2 NCKAP2 growth factor receptor-bound protein 2 2885 GRB2_HUMAN downstream 17q24-q25 75318076 75405708 -1   NM_002086 NP_002077 ####### Grb2;Mus musculus,drk;Drosophila melanogaster,Grb2;Rattus norvegicus,sem-5;Caenorhabditis elegans,grb2b;Danio rerio,grb2a;Danio rerio
123 FOXO3 AF6q21 FOXO2 FKHRL1 FOXO3A forkhead box O3 2309 FOXO3_HUMAN model,human_link 6q21 1.09E+08 1.09E+08 1   NM_001455 NP_001446 11884717,15767565,12239572,11154281,11884591,11242085,15604409,8247153,14501182,12882324,12845331,11381260,12763525,12801727,19896443,14604822,12855809,12750521,10102273,11607034,12424797,9360933,10428762,10783894,14976264,14506287,14980222,11964479,15295107,15308771,15190176,15383658,15192154,15565107,15895074,15888324,15820683,15905404,16186101,15930121,16288288,14713953,16631584,16631585,16890541,16288037,12908874,9789046,17446436,17254970,18765803,21113129,22546858,19196970,15084260,9353126,15175753,19652361,24035192,25470651,17895391,27071935 foxo3b;Danio rerio,foxo;Drosophila melanogaster,Foxo3;Mus musculus,daf-16;Caenorhabditis elegans,Foxo3;Rattus norvegicus,foxo3a;Danio rerio,HCM1;Saccharomyces cerevisiae
124 FOXO1 FKH1 FKHR FOXO1A forkhead box O1 2308 FOXO1_HUMAN model 13q14.1 40555664 40666597 -1   NM_002015 NP_002006 15767565,12843179,11242085,14501182,12882324,12845331,11381260,12763525,12801727,12750521,11607034,12424797,9360933,10428762,10783894,14506287,15295107,15220471,14871929,15190176,15192154,15888324,15905404,12530968,16186101,16099946,16288288,15546000,16631584,16631585,9789046,18301748,17446436,17254970,20222901,19426753,20519497,21149440,12219087,9353126,15582274,15272020 foxo;Drosophila melanogaster,Foxo1;Mus musculus,Foxo1;Rattus norvegicus,daf-16;Caenorhabditis elegans,foxo1b;Danio rerio,foxo1a;Danio rerio,HCM1;Saccharomyces cerevisiae
125 HSF1 HSTF1 heat shock transcription factor 1 3297 HSF1_HUMAN model 8q24.3 1.44E+08 1.44E+08 1   NM_005526 NP_005517 ####### hsf1;Schizosaccharomyces pombe,Hsf1;Mus musculus,Hsf;Drosophila melanogaster,hsf1;Danio rerio,Hsf1;Rattus norvegicus,hsf-1;Caenorhabditis elegans,HSF1;Saccharomyces cerevisiae
126 XPA XPAC XP1 xeroderma pigmentosum, complementation group A 7507 XPA_HUMAN functional,putative 9q22.3 97674909 97697409 -1   NM_000380 NP_000371 ####### rhp14;Schizosaccharomyces pombe,Xpa;Mus musculus,Xpac;Drosophila melanogaster,xpa-1;Caenorhabditis elegans,Xpa;Rattus norvegicus,xpa;Danio rerio,RAD14;Saccharomyces cerevisiae
127 MSRA   methionine sulfoxide reductase A 4482 MSRA_HUMAN mammal,model 8p23.1 10054269 10428891 1   NM_012331 NP_036463 ####### mxr1;Schizosaccharomyces pombe,Msra;Rattus norvegicus,Eip71CD;Drosophila melanogaster,Msra;Mus musculus,msra-1;Caenorhabditis elegans,msra;Danio rerio,MXR1;Saccharomyces cerevisiae
128 RECQL4 RecQ4 RecQ helicase-like 4 9401 RECQ4_HUMAN functional 8q24.3 1.45E+08 1.45E+08 -1   NM_004260 NP_004251 ####### RecQ4;Drosophila melanogaster,Recql4;Mus musculus,Recql4;Rattus norvegicus,RECQL4;Danio rerio,SGS1;Saccharomyces cerevisiae
129 SOD2   superoxide dismutase 2, mitochondrial 6648 SODM_HUMAN mammal,model 6q25.3 1.6E+08 1.6E+08 -1 HS_SOD2 NM_000636 NP_000627 12743125,11514315,12239572,10968795,12815103,14679299,12456885,11226230,7493016,9927656,9462746,12624725,8790408,11382788,15308771,14980699,12072463,7593237,15664623,15621215,12067840,16186101,16129095,15933380,16139868,16288288,16260109,16298100,16298747,16500693,16518719,16563232,16581216,16213688,10425186,16281056,15954861,17403371,18599449,17641201,17129739,15130751,21108731,19805130,19197346,19633237,9887369,20003469,9774481,21109198,15452146,16687508,19428448,19478076,15059885,19652361,25016531,26240345 SPBC16A3.14;Schizosaccharomyces pombe,Sod2;Mus musculus,Sod2;Rattus norvegicus,Sod2;Drosophila melanogaster,sod-2;Caenorhabditis elegans,sod-3;Caenorhabditis elegans,sod2;Danio rerio,SOD2;Saccharomyces cerevisiae
130 SOD1 IPOA ALS ALS1 superoxide dismutase 1, soluble 6647 SODC_HUMAN model 21q22.11 31659622 31668930 1 HS_SOD1 NM_000454 NP_000445 8108730,12743125,9620775,8673102,10719757,1383769,12871978,10968795,12815103,12675104,11166032,8643599,8610185,8209258,8351519,2960971,9228005,8650157,7492966,11382788,14993600,15295107,12072463,7593237,15664623,15897889,10381207,12067840,9858546,16260109,16298100,16298747,16500693,16518719,16563232,16581216,16213688,16636275,15130751,12060716,7588627,16723396,11114261,25003023 sod1;Schizosaccharomyces pombe,Sod1;Mus musculus,Sod1;Rattus norvegicus,sod1;Danio rerio,Sod;Drosophila melanogaster,sod-4;Caenorhabditis elegans,SOD1;Saccharomyces cerevisiae
131 FOXM1 HFH-11 trident HNF-3 INS-1 MPP2 MPHOSPH2 TGT3 FKHL16 forkhead box M1 2305 FOXM1_HUMAN functional 12p13 2857681 2877155 -1   NM_021953 NP_068772 ####### Foxm1;Mus musculus,Foxm1;Rattus norvegicus,fkh-9;Caenorhabditis elegans,foxm1;Danio rerio,HCM1;Saccharomyces cerevisiae
132 COQ7 CLK-1 CAT5 coenzyme Q7 homolog, ubiquinone (yeast) 10229 COQ7_HUMAN model 16p12.3 19067595 19080095 1   NM_016138 NP_057222 ####### coq7;Schizosaccharomyces pombe,Coq7;Rattus norvegicus,Coq7;Mus musculus,COQ7;Drosophila melanogaster,clk-1;Caenorhabditis elegans,coq7;Danio rerio,CAT5;Saccharomyces cerevisiae
133 CACNA1A Cav2.1 EA2 APCA HPCA FHM CACNL1A4 SCA6 MHP1 MHP calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 773 CAC1A_HUMAN putative 19p13 13206442 13506460 -1   NM_000068 NP_000059 ####### Cacna1a;Mus musculus,Cacna1a;Rattus norvegicus,cac;Drosophila melanogaster,unc-2;Caenorhabditis elegans,nalcn;Danio rerio,CCH1;Saccharomyces cerevisiae
134 LRP2 gp330 DBS low density lipoprotein receptor-related protein 2 4036 LRP2_HUMAN downstream 2q31.1 1.69E+08 1.69E+08 -1   NM_004525 NP_004516 ####### lrp2a;Danio rerio,Lrp2;Mus musculus,Lrp2;Rattus norvegicus,lrp-1;Caenorhabditis elegans,mgl;Drosophila melanogaster
135 AIFM1 AIF CMTX4 PDCD8 NAMSD apoptosis-inducing factor, mitochondrion-associated, 1 9131 AIFM1_HUMAN functional Xq26.1 1.3E+08 1.3E+08 -1   NM_004208 NP_004199 ####### Aifm1;Mus musculus,AIF;Drosophila melanogaster,Aifm1;Rattus norvegicus,wah-1;Caenorhabditis elegans,aifm1;Danio rerio
136 UCHL1 PGP9.5 Uch-L1 PARK5 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 7345 UCHL1_HUMAN putative 4p14 41256881 41268429 1 HS_UCHL1 NM_004181 NP_004172 ####### uch1;Schizosaccharomyces pombe,Uchl1;Mus musculus,Uchl1;Rattus norvegicus,Uch;Drosophila melanogaster,ubh-1;Caenorhabditis elegans,ubh-3;Caenorhabditis elegans,uchl1;Danio rerio,YUH1;Saccharomyces cerevisiae,ubh-2;Caenorhabditis elegans
137 APP AD1 amyloid beta (A4) precursor protein 351 A4_HUMAN putative 21q21.3 25880550 26170820 -1 HS_APP NM_000484 NP_000475 12708616,12150997,10611368,9796810,1302033,1925564,8346443,10959035,9697696,15176485,11528419,15174014,11567612,10206645,11959919,11901170,12398927,12470843,11520987,16554819,15339646,7704018,15778722,16751189,16641106,16815330,16914869,16923396,22120149,22801501,11978814,12761548,9114023,16687508,16723396,8705854 App;Mus musculus,App;Rattus norvegicus,appa;Danio rerio,appb;Danio rerio
138 APOE AD2 apolipoprotein E 348 APOE_HUMAN human_link 19q13.2 44905748 44909395 1 HS_APOE NM_000041 NP_000032 8136829,10611368,14724064,14688198,8346443,1411543,3283935,7544347,15365129,14718482,12431986,7583250,15584785,15519757,15477624,15461196,15621215,11173885,10571241,10702411,15919593,16079201,7498401,15013661,18054318,19046569,11726538,21418511,22883908,23990795,10587578,24497847,25476875,17234687 Apoe;Mus musculus,Apoe;Rattus norvegicus,apoeb;Danio rerio,apoea;Danio rerio
139 A2M FWP007 S863-7 CPAMD5 alpha-2-macroglobulin 2 A2MG_HUMAN putative 12p13.31 9067708 9115962 -1   NM_000014 NP_000005 ####### CABZ01075618.1;Danio rerio,si:ch211-212c13.8;Danio rerio,zgc:171426;Danio rerio,A2m;Rattus norvegicus,Tep2;Drosophila melanogaster,Tep3;Drosophila melanogaster,Tep1;Drosophila melanogaster,Tep4;Drosophila melanogaster,Tep5;Drosophila melanogaster,Mcr;Drosophila melanogaster,A2m;Mus musculus,;Danio rerio,;Danio rerio,;Danio rerio,;Danio rerio,;Danio rerio,;Danio rerio,;Danio rerio,a2ml;Danio rerio,;Danio rerio,;Danio rerio,LOC100911545;Rattus norvegicus
140 SNCG BCSG1 SR persyn synuclein, gamma (breast cancer-specific protein 1) 6623 SYUG_HUMAN upstream 10q23.2-q2 86958531 86963260 1   NM_003087 NP_003078 ####### Sncg;Mus musculus,Sncg;Rattus norvegicus
141 PRDX1 NKEFA PAGA peroxiredoxin 1 5052 PRDX1_HUMAN functional,putative 1p34.1 45511035 45521938 -1   NM_181697 NP_859048 ####### AABR07012795.1;Rattus norvegicus,Prdx1;Mus musculus,CG6888;Drosophila melanogaster,Jafrac1;Drosophila melanogaster,Prdx1;Rattus norvegicus,prdx-2;Caenorhabditis elegans,prdx1;Danio rerio,TSA2;Saccharomyces cerevisiae,TSA1;Saccharomyces cerevisiae
142 PON1 ESA PON paraoxonase 1 5444 PON1_HUMAN putative 7q21.3 95298357 95324572 -1   NM_000446 NP_000437 ####### Pon1;Mus musculus,Pon1;Rattus norvegicus,poml-2;Caenorhabditis elegans,mec-6;Caenorhabditis elegans,pon2;Danio rerio,pon1;Danio rerio,pon3.2;Danio rerio,pon3.2;Danio rerio,poml-4;Caenorhabditis elegans,poml-3;Caenorhabditis elegans
143 RELA p65 NFKB3 v-rel avian reticuloendotheliosis viral oncogene homolog A 5970 TF65_HUMAN functional 11q13 65653596 65662972 -1 HS_RELA NM_021975 NP_068810 8051093,9989825,10094826,12380689,12020944,11491660,11291593,10978675,9143018,11533489,10485710,10485711,11931769,12470896,10894547,11713531,12150997,7603567,12391591,10754263,11493922,12424381,16183991,15152190,18599449,22706308,19135889,21738489,9660950,23159929,23019125,16723383,23636330,23521863,15685170,15685173,12392794,9011632,12529332 Rela;Mus musculus,Dif;Drosophila melanogaster,dl;Drosophila melanogaster,Rela;Rattus norvegicus,rela;Danio rerio
144 IL6 IL-6 BSF2 HGF HSF IFNB2 interleukin 6 3569 IL6_HUMAN putative 7p21 22727147 22732002 1 HS_IL6_2 NM_000600 NP_000591 ####### Il6;Mus musculus,Il6;Rattus norvegicus
145 RGN SMP30 RC regucalcin 9104 RGN_HUMAN putative Xp11.3 47078355 47093314 1   NM_004683 NP_004674 ####### Rgn;Mus musculus,Rgn;Rattus norvegicus,regucalcin;Drosophila melanogaster,smp-30;Drosophila melanogaster,rgn;Danio rerio
146 ATP5O OSCP ATPO ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit 539 ATPO_HUMAN model 21q22.11 33903453 33915854 -1 HS_ATP5O NM_001697 NP_001688 ####### atp5;Schizosaccharomyces pombe,Atp5o;Mus musculus,Oscp;Drosophila melanogaster,atp-3;Caenorhabditis elegans,Atp5o;Rattus norvegicus,atp5o;Danio rerio,ATP5;Saccharomyces cerevisiae
147 RAD52   RAD52 homolog, DNA repair protein 5893 RAD52_HUMAN cell,functional 12p13-p12. 912077 990053 -1   NM_002879 NP_002870 ####### Rad52;Mus musculus,Rad52;Rattus norvegicus,rad52;Danio rerio,RAD52;Saccharomyces cerevisiae
148 TOP3B   topoisomerase (DNA) III beta 8940 TOP3B_HUMAN functional,putative 22q11.22 21957025 21982843 -1   NM_003935 NP_003926 ####### Top3b;Mus musculus,Top3beta;Drosophila melanogaster,Y48C3A.14;Caenorhabditis elegans,Top3b;Rattus norvegicus,top3b;Danio rerio,TOP3;Saccharomyces cerevisiae
149 ERCC1 RAD10 excision repair cross-complementation group 1 2067 ERCC1_HUMAN mammal,functional 19q13.32 45413434 45423562 -1 HS_ERCC1 NM_202001 NP_973730 ####### swi10;Schizosaccharomyces pombe,Ercc1;Mus musculus,Ercc1;Drosophila melanogaster,ercc-1;Caenorhabditis elegans,Ercc1;Rattus norvegicus,RAD10;Saccharomyces cerevisiae,ercc1;Danio rerio
150 SIRT1 SIR2L1 sirtuin 1 23411 SIRT1_HUMAN mammal,model,cell 10q21.3 67884669 67918390 1   NM_012238 NP_036370 11242085,10521401,12482959,12459580,15604409,12524341,12006491,11672523,12960381,14976264,15189148,11672522,14980222,15220471,15175761,15520384,15254550,15205477,12024027,16054100,16098828,9278054,16219030,16286010,16257164,16293764,16183991,16079181,15310905,16269335,16288288,15941577,16443777,16366736,16441846,16170353,12887892,16207712,16628003,16751189,16873059,16892051,15152190,16288037,16596166,16939484,16756498,17347648,18054318,16940753,18203716,18599449,17877786,17908559,18590691,17446436,17180656,16923962,22546858,22169038,20023410,19229036,19299583,19286518,20008932,18550784,19503100,20622856,21187328,18799131,20631301,20020036,20869593,18662547,18184747,24011076,23791176,21938067,23473037,21651395,19295512,20668205,15744310,18835033,19041753,17581637,24145446,23941528,25440059,24936455,25100619,18335035,25389371,17505061,17895433,18704159,17996922,27732836,27346580 Sirt1;Rattus norvegicus,Sir2;Drosophila melanogaster,Sirt1;Mus musculus,sir-2.1;Caenorhabditis elegans,sirt1;Danio rerio,SIR2;Saccharomyces cerevisiae,HST1;Saccharomyces cerevisiae
151 HDAC1 HD1 GON-10 RPD3L1 histone deacetylase 1 3065 HDAC1_HUMAN functional 1p34 32292107 32333623 1 HS_HDAC1 NM_004964 NP_004955 ####### Gm10093;Mus musculus,Rpd3;Drosophila melanogaster,Hdac1l;Rattus norvegicus,hda-3;Caenorhabditis elegans,hda-1;Caenorhabditis elegans,hdac1;Danio rerio,Hdac1;Rattus norvegicus,Hdac1;Mus musculus,RPD3;Saccharomyces cerevisiae
152 HSPA9 GRP75 PBP74 mot-2 mthsp75 HSPA9B heat shock 70kDa protein 9 (mortalin) 3313 GRP75_HUMAN model 5q31.1 1.39E+08 1.39E+08 -1 HS_HSPA9B_1 NM_004134 NP_004125 ####### ssp1;Schizosaccharomyces pombe,Hspa9;Mus musculus,Hsc70-5;Drosophila melanogaster,hsp-6;Caenorhabditis elegans,Hspa9;Rattus norvegicus,hspa9;Danio rerio,SSC1;Saccharomyces cerevisiae
153 GPX1   glutathione peroxidase 1 2876 GPX1_HUMAN functional 3p21.3 49357176 49358358 -1 HS_GPX1 NM_000581 NP_000572 ############################################################################################################################################################################################################################################################### Gpx1;Mus musculus,Gpx1;Rattus norvegicus,gpx-5;Caenorhabditis elegans,gpx-3;Caenorhabditis elegans,gpx-4;Caenorhabditis elegans,GPX1;Saccharomyces cerevisiae,HYR1;Saccharomyces cerevisiae
154 GSR   glutathione reductase 2936 GSHR_HUMAN functional 8p21.1 30678063 30727969 -1   NM_000637 NP_000628 ####### pgr1;Schizosaccharomyces pombe,Gsr;Mus musculus,Gsr;Rattus norvegicus,gsr-1;Caenorhabditis elegans,gsr;Danio rerio,GLR1;Saccharomyces cerevisiae
155 GSS   glutathione synthetase 2937 GSHB_HUMAN functional 20q11.2 34928433 34955798 -1 HS_GSS NM_000178 NP_000169 ####### gsa1;Schizosaccharomyces pombe,Gss;Mus musculus,Gss;Rattus norvegicus,CG32495;Drosophila melanogaster,GS;Drosophila melanogaster,gss-1;Caenorhabditis elegans,CG32495;Drosophila melanogaster,GS;Drosophila melanogaster,gss;Danio rerio,GSH2;Saccharomyces cerevisiae
156 GSTA4   glutathione S-transferase alpha 4 2941 GSTA4_HUMAN functional 6p12.1 52977948 52995380 -1   NM_001512 NP_001503 ####### gst-6;Caenorhabditis elegans,gst-7;Caenorhabditis elegans,gst-20;Caenorhabditis elegans,gst-16;Caenorhabditis elegans,gst-19;Caenorhabditis elegans,gst-27;Caenorhabditis elegans,gst-40;Caenorhabditis elegans,gst-3;Caenorhabditis elegans,gst-2;Caenorhabditis elegans,gst-4;Caenorhabditis elegans,gst-33;Caenorhabditis elegans,gst-22;Caenorhabditis elegans,gst-8;Caenorhabditis elegans,gst-38;Caenorhabditis elegans,gst-24;Caenorhabditis elegans,gst-12;Caenorhabditis elegans,gst-14;Caenorhabditis elegans,gst-15;Caenorhabditis elegans,gst-17;Caenorhabditis elegans,gst-18;Caenorhabditis elegans,gst-5;Caenorhabditis elegans,gst-9;Caenorhabditis elegans,gst-36;Caenorhabditis elegans,gst-13;Caenorhabditis elegans,gst-37;Caenorhabditis elegans,gst-26;Caenorhabditis elegans,gst-28;Caenorhabditis elegans,gst-29;Caenorhabditis elegans,gst-39;Caenorhabditis elegans,gst-31;Caenorhabditis elegans,gst-32;Caenorhabditis elegans,gst-30;Caenorhabditis elegans,gst-21;Caenorhabditis elegans,gst-35;Caenorhabditis elegans,gst-34;Caenorhabditis elegans,gsta.1;Danio rerio,gsta.2;Danio rerio,gsta.2;Danio rerio
157 GSTP1 GSTP FAEES3 GST3 glutathione S-transferase pi 1 2950 GSTP1_HUMAN functional 11q13 67583595 67586653 1 HS_GSTP1 NM_000852 NP_000843 ####### Gstp2;Mus musculus,Gstp1;Mus musculus,Gstp1;Rattus norvegicus,gstp1;Danio rerio,gst-1;Caenorhabditis elegans,gst-41;Caenorhabditis elegans,gst-23;Caenorhabditis elegans,gstp2;Danio rerio,gst-25;Caenorhabditis elegans
158 MT-CO1 COX1 COI MTCO1 mitochondrially encoded cytochrome c oxidase I 4512 COX1_HUMAN cell,functional 7444 7518 0   NM_173704 NP_776052 ####### cox1;Schizosaccharomyces pombe,mt-Co1;Mus musculus,Mt-co1;Rattus norvegicus,mt-co1;Danio rerio,COX1;Saccharomyces cerevisiae,ctc-1;Caenorhabditis elegans,mt:CoI;Drosophila melanogaster
159 HSPD1 GroEL HSP60 SPG13 heat shock 60kDa protein 1 (chaperonin) 3329 CH60_HUMAN functional 2q33.1 1.97E+08 1.97E+08 -1 HS_HSPD1 NM_002156 NP_002147 ####### hsp60;Schizosaccharomyces pombe,Hspd1;Mus musculus,Hsp60;Drosophila melanogaster,Hsp60C;Drosophila melanogaster,Hsp60D;Drosophila melanogaster,Hsp60B;Drosophila melanogaster,Hspd1;Rattus norvegicus,hsp-60;Caenorhabditis elegans,hspd1;Danio rerio,HSP60;Saccharomyces cerevisiae
160 HSPA1A HSP70-1 HSPA1 heat shock 70kDa protein 1A 3303 HSP71_HUMAN mammal,model,functional,putative 6p21.3 31815514 31817942 1 HS_HSPA1A NM_005345 NP_005336 9363888,12470898,12814804,11518492,10360681,7737368,7988669,8934873,15176485,11226747,11448943,10205060,12677068,7977810,12470839,12115981,11382788,8473688,1491731,15078873,15063109,9821948,15013664,15308771,15970415,16139996,16254069,16518701,19072255,18223156,16723383,7706448,9637782,15695762,17304350,27582425 Hspa1b;Mus musculus,Hspa1a;Rattus norvegicus,hsp70.3;Danio rerio,Hsc70-1;Drosophila melanogaster,Hsc70-4;Drosophila melanogaster,hsp-1;Caenorhabditis elegans,Hspa1a;Mus musculus,Hspa1b;Rattus norvegicus,hsp70l;Danio rerio,si:ch211-199o1.2;Danio rerio,SSA1;Saccharomyces cerevisiae,Hspa1a;Rattus norvegicus,Hspa1b;Rattus norvegicus
161 HSPA1B HSP70-2 heat shock 70kDa protein 1B 3304 HSP71_HUMAN functional,putative 6p21.3 3075514 3078033 1   NM_005346 NP_005337 ####### Hspa1b;Mus musculus,Hspa1a;Rattus norvegicus,hsp70.3;Danio rerio,Hsc70-1;Drosophila melanogaster,Hsc70-4;Drosophila melanogaster,hsp-1;Caenorhabditis elegans,Hspa1a;Mus musculus,Hspa1b;Rattus norvegicus,hsp70l;Danio rerio,si:ch211-199o1.2;Danio rerio,SSA1;Saccharomyces cerevisiae,Hspa1a;Rattus norvegicus,Hspa1b;Rattus norvegicus
162 PCMT1   protein-L-isoaspartate (D-aspartate) O-methyltransferase 5110 PIMT_HUMAN functional,putative 6q24-q25 1.5E+08 1.5E+08 1   NM_005389 NP_005380 ####### pcm2;Schizosaccharomyces pombe,Pcmt1;Rattus norvegicus,Pcmt1;Mus musculus,pcmt;Danio rerio,Pcmt;Drosophila melanogaster,pcm-1;Caenorhabditis elegans
163 MAPK8 JNK JNK1 SAPK1 PRKM8 mitogen-activated protein kinase 8 5599 MK08_HUMAN model 10q11.22 48401612 48439359 1   NM_139049 NP_620637 ############################################################################################################################################################################################################################################################### Mapk8;Mus musculus,bsk;Drosophila melanogaster,mapk8b;Danio rerio,Mapk8;Rattus norvegicus,jnk-1;Caenorhabditis elegans,mapk8a;Danio rerio,HOG1;Saccharomyces cerevisiae
164 YWHAZ KCIP-1 14-3-3-zeta YWHAD tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 7534 1433Z_HUMAN downstream 8q23.1 1.01E+08 1.01E+08 -1   NM_145690 NP_663723 ####### Ywhaz;Mus musculus,Ywhaz;Rattus norvegicus,14-3-3zeta;Drosophila melanogaster,par-5;Caenorhabditis elegans,ftt-2;Caenorhabditis elegans,M117.3;Caenorhabditis elegans,BMH2;Saccharomyces cerevisiae,BMH1;Saccharomyces cerevisiae
165 PTK2B CAKB PYK2 RAFTK PTK CADTK FAK2 protein tyrosine kinase 2 beta 2185 FAK2_HUMAN downstream 8p21.1 27311482 27459391 1   NM_173174 NP_775266 ####### Ptk2b;Mus musculus,Ptk2b;Rattus norvegicus,kin-32;Caenorhabditis elegans,ptk2bb;Danio rerio,ptk2ba;Danio rerio
166 PTK2 FAK FADK FAK1 PPP1R71 protein tyrosine kinase 2 5747 FAK1_HUMAN downstream 8q24.3 1.41E+08 1.41E+08 -1   NM_153831 NP_722560 ####### ptk2aa;Danio rerio,Ptk2;Mus musculus,Ptk2;Rattus norvegicus,Fak;Drosophila melanogaster,ptk2ab;Danio rerio,kin-32;Caenorhabditis elegans
167 IL7 IL-7 interleukin 7 3574 IL7_HUMAN putative 8q12-q13 78732772 78805523 -1   NM_000880 NP_000871 ####### Il7;Mus musculus,Il7;Rattus norvegicus
168 MAPK14 PRKM14 p38 Mxi2 PRKM15 CSPB1 CSBP1 CSBP2 mitogen-activated protein kinase 14 1432 MK14_HUMAN cell,functional 6p21 36027677 36111236 1   NM_001315 NP_001306 12581156,10856288,10581258,9712902,12419465,10480932,12885591,10943842,11593045,11557281,12213555,14612426,8974401,7601337,16099992,16339323,16449798,16272318,16170353,12639989,15130668,16652371,21399611,11978814,19619499,10949032,11069918,14566971,24531378,25083993,25151490,24531379 Mapk14;Mus musculus,p38b;Drosophila melanogaster,p38a;Drosophila melanogaster,mapk14a;Danio rerio,Mapk14;Rattus norvegicus,pmk-2;Caenorhabditis elegans,pmk-1;Caenorhabditis elegans,mapk14b;Danio rerio,HOG1;Saccharomyces cerevisiae,p38c;Drosophila melanogaster
169 FGFR1 H2 H3 H4 H5 CEK FLG BFGFR N-SAM CD331 FLT2 KAL2 fibroblast growth factor receptor 1 2260 FGFR1_HUMAN putative 8p12 38411138 38468834 -1   NM_000604 NP_000595 ####### Fgfr1;Mus musculus,fgfr1a;Danio rerio,btl;Drosophila melanogaster,htl;Drosophila melanogaster,Fgfr1;Rattus norvegicus,egl-15;Caenorhabditis elegans,fgfr1b;Danio rerio,fgfr1bl;Danio rerio
170 SP1   Sp1 transcription factor 6667 SP1_HUMAN upstream 12q13.1 53380195 53416442 1   NM_138473 NP_612482 ####### Sp1;Mus musculus,Sp1;Rattus norvegicus,Spps;Drosophila melanogaster,sptf-2;Caenorhabditis elegans,sp1;Danio rerio
171 FLT1 VEGFR1 FLT fms-related tyrosine kinase 1 2321 VGFR1_HUMAN downstream 13q12 28300346 28495128 -1   NM_002019 NP_002010 ####### Flt1;Mus musculus,Pvr;Drosophila melanogaster,Flt1;Rattus norvegicus,flt1;Danio rerio
172 JUN c-Jun AP-1 jun proto-oncogene 3725 JUN_HUMAN upstream 1p32-p31 58780791 58784113 -1 HS_JUN NM_002228 NP_002219 ####### Jun;Mus musculus,Jun;Rattus norvegicus,Jra;Drosophila melanogaster,jun;Danio rerio
173 MED1 PBP TRAP220 RB18A DRIP230 CRSP200 CRSP1 TRIP2 PPARGBP PPARBP mediator complex subunit 1 5469 MED1_HUMAN putative 17q12 39404285 39451274 -1   NM_004774 NP_004765 ####### med1;Danio rerio,Med1;Mus musculus,MED1;Drosophila melanogaster,Med1;Rattus norvegicus
174 MAPK9 JNK2 p54a SAPK PRKM9 mitogen-activated protein kinase 9 5601 MK09_HUMAN model 5q35 1.8E+08 1.8E+08 -1   NM_002752 NP_002743 ####### Mapk9;Mus musculus,bsk;Drosophila melanogaster,Mapk9;Rattus norvegicus,jnk-1;Caenorhabditis elegans,HOG1;Saccharomyces cerevisiae,mapk9;Danio rerio
175 MAPK3 ERK1 p44mapk p44erk1 PRKM3 mitogen-activated protein kinase 3 5595 MK03_HUMAN downstream 16p11.2 30114105 30123309 -1   NM_002746 NP_002737 ####### spk1;Schizosaccharomyces pombe,Mapk3;Mus musculus,Mapk3;Rattus norvegicus,mpk-1;Caenorhabditis elegans,mapk3;Danio rerio,FUS3;Saccharomyces cerevisiae,KSS1;Saccharomyces cerevisiae,rl;Drosophila melanogaster
176 HMGB1 HMG3 SBP-1 DKFZp686A04236 HMG1 high mobility group box 1 3146 HMGB1_HUMAN downstream 13q12 30457916 30465965 -1   NM_002128 NP_002119 ####### AC135696.1;Rattus norvegicus,Dsp1;Drosophila melanogaster,hmg-1.2;Caenorhabditis elegans,hmgb1a;Danio rerio,Hmg1l1;Rattus norvegicus,hmgb1b;Danio rerio,NHP6B;Saccharomyces cerevisiae,NHP6A;Saccharomyces cerevisiae
177 CCNA2 CCNA CCN1 cyclin A2 890 CCNA2_HUMAN downstream 4q27 1.22E+08 1.22E+08 -1   NM_001237 NP_001228 ####### Ccna2;Mus musculus,CycA;Drosophila melanogaster,Ccna2;Rattus norvegicus,ccna2;Danio rerio,CLB4;Saccharomyces cerevisiae,CLB3;Saccharomyces cerevisiae,CLB1;Saccharomyces cerevisiae,CLB6;Saccharomyces cerevisiae,CLB2;Saccharomyces cerevisiae,CLB5;Saccharomyces cerevisiae
178 HMGB2 HMG2 high mobility group box 2 3148 HMGB2_HUMAN downstream 4q31 1.73E+08 1.73E+08 -1 HS_HMGB2 NM_002129 NP_002120 ####### RGD1561694;Rattus norvegicus,Hmgb2;Rattus norvegicus,Hmgb2l1;Rattus norvegicus,Hmgb2;Mus musculus,Dsp1;Drosophila melanogaster,hmg-1.2;Caenorhabditis elegans,Hmgb2l1;Rattus norvegicus,RGD1559962;Rattus norvegicus,hmgb2a;Danio rerio,NHP6B;Saccharomyces cerevisiae,NHP6A;Saccharomyces cerevisiae
179 MAP3K5 MAPKKK5 ASK1 MEKK5 mitogen-activated protein kinase kinase kinase 5 4217 M3K5_HUMAN downstream 6q22.33 1.37E+08 1.37E+08 -1   NM_005923 NP_005914 ####### Map3k5;Mus musculus,Pk92B;Drosophila melanogaster,Map3k5;Rattus norvegicus,map3k5;Danio rerio,STE11;Saccharomyces cerevisiae,BCK1;Saccharomyces cerevisiae,nsy-1;Caenorhabditis elegans
180 TAF1 NSCL2 TAFII250 KAT4 DYT3/TAF1 TAF2A BA2R CCG1 CCGS DYT3 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa 6872 TAF1_HUMAN downstream Xq13.1 71366239 71466005 1   NM_138923 NP_620278 ####### Taf1;Drosophila melanogaster,taf-1;Caenorhabditis elegans,Taf1;Mus musculus,taf1;Danio rerio,TAF1;Saccharomyces cerevisiae
181 LMNB1   lamin B1 4001 LMNB1_HUMAN functional 5q23.2 1.27E+08 1.27E+08 1   NM_005573 NP_005564 ####### Lmnb1;Mus musculus,Lam;Drosophila melanogaster,LamC;Drosophila melanogaster,Lmnb1;Rattus norvegicus,lmn-1;Caenorhabditis elegans,lmnb1;Danio rerio
182 SDHC CYB560 PGL3 succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 6391 C560_HUMAN model 1q23.3 1.61E+08 1.61E+08 1 HS_SDHC NM_003001 NP_002992 ####### sdh3;Schizosaccharomyces pombe,CG6629;Drosophila melanogaster,SdhC;Drosophila melanogaster,Sdhc;Mus musculus,mev-1;Caenorhabditis elegans,Sdhc;Rattus norvegicus,sdhc;Danio rerio
183 FOXO4 AFX1 MLLT7 forkhead box O4 4303 FOXO4_HUMAN model Xq13.1 71096149 71103534 1   NM_005938 NP_005929 ####### sep1;Schizosaccharomyces pombe,foxo;Drosophila melanogaster,Foxo4;Mus musculus,daf-16;Caenorhabditis elegans,Foxo4;Rattus norvegicus,foxo4;Danio rerio,HCM1;Saccharomyces cerevisiae
184 HESX1 RPX ANF HESX homeobox 1 8820 HESX1_HUMAN upstream 3p14.3 57197916 57200252 -1   NM_003865 NP_003856 ####### hesx1;Danio rerio,Hesx1;Mus musculus,Hesx1;Rattus norvegicus
185 PIK3R1 GRB1 p85-ALPHA p85 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 5295 P85A_HUMAN downstream 5q13.1 68215756 68301821 1   NM_181523 NP_852664 ####### Pik3r1;Mus musculus,Pik3r1;Rattus norvegicus,Pi3K21B;Drosophila melanogaster,aap-1;Caenorhabditis elegans,pik3r1;Danio rerio
186 BSCL2 GNG3LG SPG17 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 26580 BSCL2_HUMAN putative 11q13 62690262 62706315 -1   NM_032667 NP_116056 ####### SPAC3A11.04;Schizosaccharomyces pombe,Bscl2;Rattus norvegicus,Bscl2;Mus musculus,Seipin;Drosophila melanogaster,bscl2l;Danio rerio,bscl2;Danio rerio
187 AGPAT2 LPAAT-beta BSCL 1-acylglycerol-3-phosphate O-acyltransferase 2 10555 PLCB_HUMAN putative 9q34.3 1.37E+08 1.37E+08 -1   NM_006412 NP_006403 ####### CG3812;Drosophila melanogaster,fu12;Drosophila melanogaster,Agpat2;Mus musculus,acl-2;Caenorhabditis elegans,acl-1;Caenorhabditis elegans,Agpat2;Rattus norvegicus,agpat2;Danio rerio,SLC1;Saccharomyces cerevisiae
188 BMI1 RNF51 PCGF4 BMI1 proto-oncogene, polycomb ring finger 648 BMI1_HUMAN putative 10p11.23 22321210 22331485 1   NM_005180 NP_005171 ####### Bmi1;Mus musculus,Psc;Drosophila melanogaster,Su(z)2;Drosophila melanogaster,Bmi1;Rattus norvegicus,bmi1a;Danio rerio,bmi1b;Danio rerio
189 EEF1A1 EE1A1 EF1A EEF1A LENG7 eukaryotic translation elongation factor 1 alpha 1 1915 EF1A1_HUMAN model 6q14.1 73515750 73521032 -1   NM_001402 NP_001393 ####### LOC100360413;Rattus norvegicus,LOC100911991;Rattus norvegicus,Eef1a1;Mus musculus,Ef1alpha100E;Drosophila melanogaster,Eef1a1;Rattus norvegicus,eef1a1a;Danio rerio,TEF1;Saccharomyces cerevisiae,TEF1;Saccharomyces cerevisiae,eef1a1b;Danio rerio
190 TFAP2A AP-2 TFAP2 AP2TF transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 7020 AP2A_HUMAN upstream 6p24 10396683 10415237 -1   NM_003220 NP_003211 ####### Tfap2a;Mus musculus,TfAP-2;Drosophila melanogaster,tfap2a;Danio rerio,aptf-1;Caenorhabditis elegans,Tfap2a;Rattus norvegicus
191 BDNF   brain-derived neurotrophic factor 627 BDNF_HUMAN putative 11p13 27654895 27659649 -1   NM_170735 NP_733931 ############################################################################################################################################################################################################################################################### Bdnf;Mus musculus,Bdnf;Rattus norvegicus,bdnf;Danio rerio
192 CREB1   cAMP responsive element binding protein 1 1385 CREB1_HUMAN upstream,putative 2q34 2.08E+08 2.08E+08 1   NM_134442 NP_604391 ####### Creb1;Mus musculus,CrebB;Drosophila melanogaster,Creb1;Rattus norvegicus,crh-1;Caenorhabditis elegans,creb1b;Danio rerio,creb1a;Danio rerio,Creb1;Rattus norvegicus
193 ATF2 TREB7 CRE-BP1 HB16 CREB2 activating transcription factor 2 1386 ATF2_HUMAN downstream 2q32 1.75E+08 1.75E+08 -1   NM_001880 NP_001871 ####### Atf2;Mus musculus,Atf2;Rattus norvegicus,atf2;Danio rerio
194 TBP TFIID GTF2D1 SCA17 TATA box binding protein 6908 TBP_HUMAN upstream 6q27 1.71E+08 1.71E+08 1   NM_003194 NP_003185 ####### Tbp;Mus musculus,Tbp;Drosophila melanogaster,Tbp;Rattus norvegicus,tbp-1;Caenorhabditis elegans,tbp;Danio rerio,SPT15;Saccharomyces cerevisiae
195 APEX1 APE REF1 HAP1 APX APEN REF-1 APE-1 APEX APEX nuclease (multifunctional DNA repair enzyme) 1 328 APEX1_HUMAN functional 14q11.2 20455131 20457772 1 HS_APEX1 NM_001641 NP_001632 ####### Apex1;Mus musculus,Rrp1;Drosophila melanogaster,Apex1;Rattus norvegicus,exo-3;Caenorhabditis elegans,apex1;Danio rerio,APN2;Saccharomyces cerevisiae
196 HBP1   HMG-box transcription factor 1 26959 HBP1_HUMAN downstream 7q22-q31 1.07E+08 1.07E+08 1 HS_HBP1 NM_012257 NP_036389 ####### Hbp1;Rattus norvegicus,Hbp1;Mus musculus,hbp1;Danio rerio
197 BUB1B BUBR1 MAD3L Bub1A SSK1 BUB1 mitotic checkpoint serine/threonine kinase B 701 BUB1B_HUMAN mammal 15q15 40161009 40221136 1   NM_001211 NP_001202 ####### bub1;Schizosaccharomyces pombe,Bub1b;Mus musculus,Bub1;Drosophila melanogaster,BubR1;Drosophila melanogaster,Bub1b;Rattus norvegicus,bub-1;Caenorhabditis elegans,bub1bb;Danio rerio,BUB1;Saccharomyces cerevisiae,MAD3;Saccharomyces cerevisiae
198 PTGS2 COX2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 5743 PGH2_HUMAN putative 1q25.2-q25 1.87E+08 1.87E+08 -1   NM_000963 NP_000954 ####### Ptgs2;Mus musculus,Ptgs2;Rattus norvegicus,ptgs2a;Danio rerio,ptgs2b;Danio rerio
199 HSPA8 HSC71 HSC70 HSP73 HSPA10 heat shock 70kDa protein 8 3312 HSP7C_HUMAN functional 11q24.1 1.23E+08 1.23E+08 -1 HS_HSPA8 NM_006597 NP_006588 ####### AABR07011951.1;Rattus norvegicus,Hspa8;Rattus norvegicus,Hspa8;Rattus norvegicus,Hspa8;Mus musculus,Hsc70-1;Drosophila melanogaster,Hsc70-4;Drosophila melanogaster,hsp-1;Caenorhabditis elegans,HSPA8 (1 of many);Danio rerio,hspa8;Danio rerio,LOC680121;Rattus norvegicus,SSA1;Saccharomyces cerevisiae
200 SIN3A KIAA0700 DKFZP434K2235 SIN3 transcription regulator family member A 25942 SIN3A_HUMAN putative 15q24.2 75369379 75451585 -1   NM_015477 NP_056292 ####### Sin3a;Mus musculus,Sin3A;Drosophila melanogaster,sin-3;Caenorhabditis elegans,sin3ab;Danio rerio,Sin3a;Rattus norvegicus,sin3aa;Danio rerio,SIN3;Saccharomyces cerevisiae
201 CDK1 CDC28A CDC2 cyclin-dependent kinase 1 983 CDC2_HUMAN downstream 10q21.1 60778454 60794852 1 HS_CDC2 NM_001786 NP_001777 ####### Cdk1;Mus musculus,Cdk1;Drosophila melanogaster,Cdk1;Rattus norvegicus,cdk1;Danio rerio,cdk-1;Caenorhabditis elegans,CDC28;Saccharomyces cerevisiae
202 TFDP1 Dp-1 DRTF1 DP1 transcription factor Dp-1 7027 TFDP1_HUMAN cell,downstream 13q34 1.14E+08 1.14E+08 1   NM_007111 NP_009042 ####### Tfdp1;Mus musculus,Dp;Drosophila melanogaster,dpl-1;Caenorhabditis elegans,Tfdp1;Rattus norvegicus,tfdp1a;Danio rerio
203 DDIT3 CHOP10 GADD153 CHOP DNA-damage-inducible transcript 3 1649 DDIT3_HUMAN putative 12q13.1-q1 57516588 57520517 -1   NM_004083 NP_004074 ####### Ddit3;Mus musculus,Ddit3;Rattus norvegicus,ddit3;Danio rerio
204 POLA1 p180 POLA NSX polymerase (DNA directed), alpha 1, catalytic subunit 5422 DPOLA_HUMAN cell Xp22.1-p21 24693947 24996985 1   NM_016937 NP_058633 ####### pol1;Schizosaccharomyces pombe,Pola1;Rattus norvegicus,Pola1;Mus musculus,DNApol-alpha180;Drosophila melanogaster,Y47D3A.29;Caenorhabditis elegans,pola1;Danio rerio,POL1;Saccharomyces cerevisiae
205 MAPT MTBT1 tau PPND FTDP-17 TAU MSTD MTBT2 FLJ31424 MGC138549 PPP1R103 DDPAC MAPTL microtubule-associated protein tau 4137 TAU_HUMAN putative 17q21.1 45894382 46028333 1   NM_016835 NP_058519 10391244,8866683,11959919,10595944,11901170,15341514,14512841,12398927,12470843,12368474,11173885,11159192,7970209,8506352,10571241,10702411,10932182,11520987,15044677,9856453,10595524,11710889,16123158,16171847,16518719,16371324,11226152,7498401,16687499,16914869,16877359,22120149,11978814,20869593,18786355,8673924 mapta;Danio rerio,Mapt;Mus musculus,Mapt;Rattus norvegicus,ptl-1;Caenorhabditis elegans,tau;Drosophila melanogaster,maptb;Danio rerio
206 CTGF IGFBP8 CCN2 connective tissue growth factor 1490 CTGF_HUMAN putative 6q23.1 1.32E+08 1.32E+08 -1 HS_CTGF NM_001901 NP_001892 ####### Ctgf;Mus musculus,Ccn;Drosophila melanogaster,Ctgf;Rattus norvegicus,ctgfa;Danio rerio
207 HDAC2 RPD3 YAF1 histone deacetylase 2 3066 HDAC2_HUMAN functional,upstream 6q21 1.14E+08 1.14E+08 -1 HS_HDAC2 NM_001527 NP_001518 ####### clr6;Schizosaccharomyces pombe,Hdac2;Mus musculus,Rpd3;Drosophila melanogaster,Hdac2;Rattus norvegicus,hda-3;Caenorhabditis elegans,hda-1;Caenorhabditis elegans,RPD3;Saccharomyces cerevisiae
208 MAX bHLHd4 bHLHd5 bHLHd6 bHLHd7 bHLHd8 MYC associated factor X 4149 MAX_HUMAN functional 14q23 65075124 65102544 -1   NM_002382 NP_002373 ####### Max;Mus musculus,max;Danio rerio,Max;Drosophila melanogaster,Max;Rattus norvegicus,mxl-1;Caenorhabditis elegans,mxl-3;Caenorhabditis elegans
209 MXD1 MAD1 bHLHc58 MAD MAX dimerization protein 1 4084 MAD1_HUMAN functional 2p13-p12 69915041 69942944 1   NM_002357 NP_002348 ####### Mxd1;Mus musculus,mdl-1;Caenorhabditis elegans,Mxd1;Rattus norvegicus,mxd1;Danio rerio
210 MDM2 HDM2 MGC5370 MDM2 proto-oncogene, E3 ubiquitin protein ligase 4193 MDM2_HUMAN upstream 12q14.3-q1 68808172 68845544 1   NM_002392 NP_002383 ####### Mdm2;Mus musculus,mdm2;Danio rerio,Mdm2;Rattus norvegicus
211 SUMO1 PIC1 GMP1 SMT3C SUMO-1 SMT3H3 OFC10 UBL1 small ubiquitin-like modifier 1 7341 SUMO1_HUMAN upstream 2q33 2.02E+08 2.02E+08 -1 HS_UBL1 NM_003352 NP_003343 ####### pmt3;Schizosaccharomyces pombe,Sumo1;Mus musculus,smo-1;Caenorhabditis elegans,Sumo1;Rattus norvegicus,sumo1;Danio rerio,SMT3;Saccharomyces cerevisiae
212 H2AFX H2AX H2A histone family, member X 3014 H2AX_HUMAN functional 11q23.3 1.19E+08 1.19E+08 -1   NM_002105 NP_002096 ####### H2afx;Mus musculus,His2A:CG33826;Drosophila melanogaster,His2A:CG33847;Drosophila melanogaster,His2A:CG33865;Drosophila melanogaster,h2afx;Danio rerio,zgc:101846;Danio rerio,H2afx;Rattus norvegicus,zgc:110434;Danio rerio,HTA1;Saccharomyces cerevisiae,His2A:CG33826;Drosophila melanogaster,His2A:CG33847;Drosophila melanogaster,His2A:CG33865;Drosophila melanogaster,His2A:CG33826;Drosophila melanogaster,His2A:CG33847;Drosophila melanogaster,His2A:CG33865;Drosophila melanogaster,His2A:CG33826;Drosophila melanogaster,His2A:CG33847;Drosophila melanogaster,His2A:CG33865;Drosophila melanogaster,His2A:CG33826;Drosophila melanogaster,His2A:CG33847;Drosophila melanogaster,His2A:CG33865;Drosophila melanogaster,His2A:CG33826;Drosophila melanogaster,His2A:CG33847;Drosophila melanogaster,His2A:CG33865;Drosophila melanogaster,His2A:CG33826;Drosophila melanogaster,His2A:CG33847;Drosophila melanogaster,His2A:CG33865;Drosophila melanogaster,His2A:CG33826;Drosophila melanogaster,His2A:CG33847;Drosophila melanogaster,His2A:CG33865;Drosophila melanogaster,His2A:CG33826;Drosophila melanogaster,His2A:CG33847;Drosophila melanogaster,His2A:CG33865;Drosophila melanogaster,His2A:CG33826;Drosophila melanogaster,His2A:CG33847;Drosophila melanogaster,His2A:CG33865;Drosophila melanogaster,His2A:CG33826;Drosophila melanogaster,His2A:CG33847;Drosophila melanogaster,His2A:CG33865;Drosophila melanogaster,His2A:CG33826;Drosophila melanogaster,His2A:CG33847;Drosophila melanogaster,His2A:CG33865;Drosophila melanogaster,His2A:CG33826;Drosophila melanogaster,His2A:CG33847;Drosophila melanogaster,His2A:CG33865;Drosophila melanogaster,His2A:CG33826;Drosophila melanogaster,His2A:CG33847;Drosophila melanogaster,His2A:CG33865;Drosophila melanogaster,His2A:CG33826;Drosophila melanogaster,His2A:CG33847;Drosophila melanogaster,His2A:CG33865;Drosophila melanogaster,His2A:CG33826;Drosophila melanogaster,His2A:CG33847;Drosophila melanogaster,His2A:CG33865;Drosophila melanogaster,His2A:CG33826;Drosophila melanogaster,His2A:CG33847;Drosophila melanogaster,His2A:CG33865;Drosophila melanogaster,zgc:165551;Danio rerio,si:ch73-368j24.15;Danio rerio,zgc:165551;Danio rerio,zgc:195633;Danio rerio,zgc:195633;Danio rerio,zgc:110434;Danio rerio,si:ch1073-159d7.9;Danio rerio
213 HOXB7 HOX2 HOX2C homeobox B7 3217 HXB7_HUMAN putative 17q21.3 48607233 48611021 -1   NM_004502 NP_004493 ####### Hoxb7;Mus musculus,Antp;Drosophila melanogaster,hoxb7a;Danio rerio,Hoxb7;Rattus norvegicus
214 HOXC4 HOX3 HOX3E homeobox C4 3221 HXC4_HUMAN putative 12q13.3 54053877 54056030 1   NM_153633 NP_705897 ####### Hoxc4;Mus musculus,Hoxc4;Rattus norvegicus,hoxc4a;Danio rerio,Dfd;Drosophila melanogaster,lin-39;Caenorhabditis elegans
215 JAK2 JTK10 Janus kinase 2 3717 JAK2_HUMAN downstream 9p24 4985245 5128183 1   NM_004972 NP_004963 ####### Jak2;Mus musculus,Jak2;Rattus norvegicus,jak2b;Danio rerio,hop;Drosophila melanogaster
216 ESR1 NR3A1 Era ESR estrogen receptor 1 2099 ESR1_HUMAN upstream 6q25.1 1.52E+08 1.52E+08 1 HS_ESR1 NM_000125 NP_000116 ####### Esr1;Mus musculus,Esr1;Rattus norvegicus,esr1;Danio rerio
217 LEP OBS OB leptin 3952 LEP_HUMAN putative 7q31.3 1.28E+08 1.28E+08 1   NM_000230 NP_000221 11818964,15289464,15247061,14764310,14747284,14724075,14651995,12023258,12031989,11572787,11149898,10843181,10868965,9790175,9392492,7984236,7624776,12431986,10660043,12594516,8584938,14613274,11457594,15919793,9511737,12530968,8974400,9202122,16611697,16960019,18443001,16845389,11970899,23732375,16625210,11533494,15044360,11445560,25888600 Lep;Mus musculus,Lep;Rattus norvegicus
218 LEPR OBR CD295 leptin receptor 3953 LEPR_HUMAN putative 1p31 65420652 65637493 1   NM_002303 NP_002294 ####### Lepr;Rattus norvegicus,Lepr;Mus musculus,lepr;Danio rerio
219 NFKBIA IKBA MAD-3 IkappaBalpha NFKBI nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 4792 IKBA_HUMAN mammal,putative 14q13 35401510 35404754 -1 HS_NFKBIA NM_020529 NP_065390 ####### Nfkbia;Mus musculus,Nfkbia;Rattus norvegicus,cact;Drosophila melanogaster,nfkbiab;Danio rerio,nfkbiaa;Danio rerio
220 CLU SGP-2 SP-40 TRPM-2 KUB1 CLU1 CLU2 CLI APOJ clusterin 1191 CLUS_HUMAN model,putative 8p21-p12 27596917 27615031 -1   NM_203339 NP_976084 ####### Clu;Mus musculus,Clu;Rattus norvegicus,clu;Danio rerio
221 MTOR RAFT1 RAPT1 FLJ44809 FRAP FRAP2 FRAP1 mechanistic target of rapamycin (serine/threonine kinase) 2475 FRAP_HUMAN mammal,model,cell 1p36.2 11106531 11262551 -1   NM_004958 NP_004949 15186745,15780592,14668850,15253933,12559758,15860463,15545625,8008069,15797377,12080086,23317514,16293764,16675393,16890541,12908874,16505167,16847060,17403371,18443001,17502379,15928081,19934433,19733540,20526321,23549082,23994476,23325216,21157483,20080789,21179166,25059582,24481314,22461615,26017155,26147250,27618784 tor2;Schizosaccharomyces pombe,Tor;Drosophila melanogaster,Mtor;Mus musculus,Mtor;Rattus norvegicus,mtor;Danio rerio,TOR1;Saccharomyces cerevisiae
222 GHRHR   growth hormone releasing hormone receptor 2692 GHRHR_HUMAN upstream,putative 7p14 30964021 30979531 1   NM_000823 NP_000814 ####### Ghrhr;Mus musculus,Ghrhr;Rattus norvegicus,ghrhrl;Danio rerio
223 CTNNB1 beta-catenin armadillo CTNNB catenin (cadherin-associated protein), beta 1, 88kDa 1499 CTNB1_HUMAN downstream 3p21 41199451 41240448 1   NM_001904 NP_001895 ####### Ctnnb1;Mus musculus,ctnnb1;Danio rerio,arm;Drosophila melanogaster,Ctnnb1;Rattus norvegicus
224 PSEN1 FAD S182 PS1 AD3 presenilin 1 5663 PSN1_HUMAN putative 14q24.3 73136435 73223691 1   NM_000021 NP_000012 ####### Psen1;Mus musculus,Psen1;Rattus norvegicus,psen1;Danio rerio,Psn;Drosophila melanogaster,hop-1;Caenorhabditis elegans,spe-4;Caenorhabditis elegans,sel-12;Caenorhabditis elegans
225 DLL3 SCDO1 delta-like 3 (Drosophila) 10683 DLL3_HUMAN putative 19q13 39498917 39508481 1   NM_016941 NP_058637 ####### Dll3;Mus musculus,Dll3;Rattus norvegicus
226 CDKN2A CDK4I p16 INK4a MTS1 CMM2 ARF p19 p14 INK4 p16INK4a p19Arf p14ARF CDKN2 MLM cyclin-dependent kinase inhibitor 2A 1029 CD2A2_HUMAN mammal,cell 9p21 21967752 21975133 -1   NM_000077 NP_000068 14574365,9624006,15520862,11544530,11544531,12015983,12486224,8153634,15582292,15520276,14722607,7987387,9529248,15361884,16054100,16107615,12882406,15964994,16476774,17227869,18516091,17637672,17664422,16957737,19907431,22048312,16957738,19934433,19013273,19239418,17459456,18957199,10594030,22888763,23332765,17713536,20173736,17463246,19118192,16957735,16537449,20551323,23124852,17225865,24522534,25481981,25990896,26840489,26950362 cdkn2a/b;Danio rerio
227 PPP1CA PP1A PP-1A PP1alpha PPP1A protein phosphatase 1, catalytic subunit, alpha isozyme 5499 PP1A_HUMAN cell,putative 11q13 67398181 67401905 -1 HS_PPP1CA NM_002708 NP_002699 ####### Ppp1ca;Mus musculus,Ppp1ca;Rattus norvegicus,Pp1alpha-96A;Drosophila melanogaster,Pp1-13C;Drosophila melanogaster,Pp1-87B;Drosophila melanogaster,GLC7;Saccharomyces cerevisiae,gsp-2;Caenorhabditis elegans
228 DBN1 D0S117E drebrin 1 1627 DREB_HUMAN putative 5q35.3 1.77E+08 1.77E+08 -1   NM_004395 NP_004386 ####### app1;Schizosaccharomyces pombe,Dbn1;Mus musculus,Dbn1;Rattus norvegicus,dbn1;Danio rerio
229 NOG SYNS1 SYM1 noggin 9241 NOGG_HUMAN putative 17q22 56593699 56595590 1   NM_005450 NP_005441 ####### Nog;Mus musculus,Nog;Rattus norvegicus,nog3;Danio rerio,nog1;Danio rerio
230 ELN WBS WS SVAS elastin 2006 ELN_HUMAN human_link 7q11.23 74027789 74069906 1   NM_000501 NP_000492 ####### Eln;Mus musculus,Eln;Rattus norvegicus
231 ATR FRP1 SCKL SCKL1 MEC1 ATR serine/threonine kinase 545 ATR_HUMAN mammal 3q23 1.42E+08 1.43E+08 -1   NM_001184 NP_001175 ####### rad3;Schizosaccharomyces pombe,mei-41;Drosophila melanogaster,Atr;Mus musculus,atr;Danio rerio,Atr;Rattus norvegicus,MEC1;Saccharomyces cerevisiae
232 UCP3 SLC25A9 uncoupling protein 3 (mitochondrial, proton carrier) 7352 UCP3_HUMAN functional 11q13.4 74000281 74009237 -1   NM_003356 NP_003347 ####### Ucp3;Mus musculus,Ucp3;Rattus norvegicus,ucp3;Danio rerio,DIC1;Saccharomyces cerevisiae
233 ZMPSTE24 FACE-1 Ste24p STE24 HGPS PRO1 zinc metallopeptidase STE24 10269 FACE1_HUMAN upstream,putative 1p34 40258050 40294184 1   NM_005857 NP_005848 ####### SPAC3H1.05;Schizosaccharomyces pombe,ste24b;Drosophila melanogaster,ste24a;Drosophila melanogaster,CG7573;Drosophila melanogaster,fce-1;Caenorhabditis elegans,Zmpste24;Mus musculus,Zmpste24;Rattus norvegicus,zmpste24;Danio rerio,STE24;Saccharomyces cerevisiae,ste24c;Drosophila melanogaster
234 TP63 p51 SHFM4 EEC3 p63 p73L OFC8 KET p73H NBP p53CP TP73L TP53L TP53CP tumor protein p63 8626 P63_HUMAN mammal 3q28 1.9E+08 1.9E+08 1   NM_003722 NP_003713 ####### Trp63;Mus musculus,Tp63;Rattus norvegicus,tp63;Danio rerio
235 UCP2 SLC25A8 BMIQ4 uncoupling protein 2 (mitochondrial, proton carrier) 7351 UCP2_HUMAN model 11q13 73974671 73982844 -1 HS_UCP2 NM_003355 NP_003346 ############################################################################################################################################################################################################################################################### Ucp2;Mus musculus,Ucp2;Rattus norvegicus,ucp2;Danio rerio,DIC1;Saccharomyces cerevisiae
236 POLB   polymerase (DNA directed), beta 5423 DPOLB_HUMAN functional 8p11.2 42338455 42371813 1   NM_002690 NP_002681 ####### Polb;Mus musculus,Polb;Rattus norvegicus,polb;Danio rerio
237 GCLC GCS GLCLC GLCL glutamate-cysteine ligase, catalytic subunit 2729 GSH1_HUMAN functional 6p12 53497341 53545129 -1   NM_001498 NP_001489 ####### gcs1;Schizosaccharomyces pombe,Gclc;Mus musculus,Gclc;Rattus norvegicus,Gclc;Drosophila melanogaster,gcs-1;Caenorhabditis elegans,gclc;Danio rerio,GSH1;Saccharomyces cerevisiae
238 GCLM GLCLR glutamate-cysteine ligase, modifier subunit 2730 GSH0_HUMAN model 1p22.1 93885200 93909598 -1   NM_002061 NP_002052 ####### SPCC737.06c;Schizosaccharomyces pombe,Gclm;Mus musculus,Gclm;Rattus norvegicus,E01A2.1;Caenorhabditis elegans,Gclm;Drosophila melanogaster,gclm;Danio rerio
239 SIRT6   sirtuin 6 51548 SIRT6_HUMAN mammal 19p13.3 4174109 4182599 -1   NM_016539 NP_057623 ####### SIRT6;Danio rerio,Sirt6;Drosophila melanogaster,Sirt6;Mus musculus,sir-2.4;Caenorhabditis elegans,Sirt6;Rattus norvegicus
240 BUB3 BUB3L BUB3 mitotic checkpoint protein 9184 BUB3_HUMAN mammal 10q26 1.23E+08 1.23E+08 1 HS_BUB3 NM_004725 NP_004716 ####### bub3;Schizosaccharomyces pombe,Bub3;Mus musculus,Bub3;Drosophila melanogaster,bub-3;Caenorhabditis elegans,Bub3;Rattus norvegicus,bub3;Danio rerio,GLE2;Saccharomyces cerevisiae
241 RAE1 Mnrp41 ribonucleic acid export 1 8480 RAE1L_HUMAN mammal 20q13.31 57351089 57378463 1 HS_RAE1 NM_003610 NP_003601 ####### rae1;Schizosaccharomyces pombe,Rae1;Drosophila melanogaster,Rae1;Mus musculus,rae-1;Caenorhabditis elegans,Rae1;Rattus norvegicus,rae1;Danio rerio,GLE2;Saccharomyces cerevisiae
242 PMCH MCH pro-melanin-concentrating hormone 5367 MCH_HUMAN functional 12q23.2 1.02E+08 1.02E+08 -1   NM_002674 NP_002665 ####### Pmch;Rattus norvegicus,Pmch;Mus musculus
243 MLH1 HNPCC FCC2 HNPCC2 COCA2 mutL homolog 1 4292 MLH1_HUMAN functional,putative 3p21.3 36993350 37050846 1   NM_000249 NP_000240 ####### mlh1;Schizosaccharomyces pombe,Mlh1;Mus musculus,Mlh1;Drosophila melanogaster,Mlh1;Rattus norvegicus,mlh-1;Caenorhabditis elegans,mlh1;Danio rerio,MLH1;Saccharomyces cerevisiae
244 CSNK1E HCKIE CKIE CKIepsilon casein kinase 1, epsilon 1454 KC1E_HUMAN putative 22q13.1 38290691 38318084 -1   NM_001894 NP_001885 ####### Csnk1e;Mus musculus,dco;Drosophila melanogaster,Csnk1e;Rattus norvegicus,kin-20;Caenorhabditis elegans,HRR25;Saccharomyces cerevisiae,csnk1e;Danio rerio
245 STUB1 UBOX1 CHIP SDCCAG7 HSPABP2 NY-CO-7 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 10273 STUB1_HUMAN mammal 16p13.3 680111 682768 1 HS_STUB1 NM_005861 NP_005852 18411298 CHIP;Drosophila melanogaster,Stub1;Mus musculus,chn-1;Caenorhabditis elegans,Stub1;Rattus norvegicus,stub1;Danio rerio
246 PPM1D Wip1 PP2C-DELTA protein phosphatase, Mg2+/Mn2+ dependent, 1D 8493 PPM1D_HUMAN downstream,putative 17q23.2 60600183 60666279 1   NM_003620 NP_003611 ####### Pp2C1;Drosophila melanogaster,Ppm1d;Mus musculus,Y54F10BM.1;Caenorhabditis elegans,Ppm1d;Rattus norvegicus,ppm1da;Danio rerio,ppm1db;Danio rerio,PTC1;Saccharomyces cerevisiae
247 CHEK2 CDS1 CHK2 HuCds1 PP1425 bA444G7 RAD53 checkpoint kinase 2 11200 CHK2_HUMAN functional 22q12.1 28687743 28741834 -1   NM_001005735 NP_001005735 ####### cds1;Schizosaccharomyces pombe,lok;Drosophila melanogaster,Chek2;Mus musculus,Chek2;Rattus norvegicus,chk-2;Caenorhabditis elegans,T08D2.7;Caenorhabditis elegans,chek2;Danio rerio,RAD53;Saccharomyces cerevisiae
248 PCK1 PEPCK-C phosphoenolpyruvate carboxykinase 1 (soluble) 5105 PCKGC_HUMAN putative 20q13.31 57561081 57566457 1   NM_002591 NP_002582 ####### Pck1;Mus musculus,CG10924;Drosophila melanogaster,Pepck;Drosophila melanogaster,pck-2;Caenorhabditis elegans,pck-1;Caenorhabditis elegans,pck-3;Caenorhabditis elegans,Pck1;Rattus norvegicus,pck1;Danio rerio
249 ARHGAP1 RhoGAP p50rhoGAP CDC42GAP Cdc42GAP Rho GTPase activating protein 1 392 RHG01_HUMAN mammal 11p11.2 46677075 46700665 -1   NM_004308 NP_004299 17227869 RhoGAP68F;Drosophila melanogaster,rga-1;Caenorhabditis elegans,Arhgap1;Mus musculus,Arhgap1;Rattus norvegicus,arhgap1;Danio rerio
250 CDC42 G25K CDC42Hs cell division cycle 42 998 CDC42_HUMAN cell,downstream 1p36.1 22052627 22092943 1   NM_001791 NP_001782 ####### cdc42;Schizosaccharomyces pombe,Cdc42;Mus musculus,Cdc42;Drosophila melanogaster,Cdc42;Rattus norvegicus,cdc42;Danio rerio,CDC42;Saccharomyces cerevisiae
251 ARNTL MOP3 JAP3 BMAL1 PASD3 bHLHe5 aryl hydrocarbon receptor nuclear translocator-like 406 BMAL1_HUMAN mammal 11p15 13277727 13387265 1   NM_001178 NP_001169 ####### Arntl;Mus musculus,Arntl;Rattus norvegicus,cyc;Drosophila melanogaster,arntl1a;Danio rerio,arntl1b;Danio rerio
252 CLOCK KIAA0334 KAT13D bHLHe8 clock circadian regulator 9575 CLOCK_HUMAN functional,downstream 4q12 55427901 55546909 -1   NM_004898 NP_004889 ####### Clock;Mus musculus,clocka;Danio rerio,Clk;Drosophila melanogaster,Clock;Rattus norvegicus,clockb;Danio rerio
253 HIC1 ZBTB29 ZNF901 hypermethylated in cancer 1 3090 HIC1_HUMAN upstream 17p13.3 2055099 2059687 1   NM_006497 NP_006488 ####### Hic1;Rattus norvegicus,Hic1;Mus musculus,hic1;Danio rerio,LOC100912068;Rattus norvegicus
254 PAPPA PAPP-A PAPPA1 IGFBP-4ase PAPA ASBABP2 DIPLA1 pregnancy-associated plasma protein A, pappalysin 1 5069 PAPP1_HUMAN functional,putative 9q33.2 1.16E+08 1.16E+08 1   NM_002581 NP_002572 ####### pappaa;Danio rerio,Pappa;Mus musculus,Pappa;Rattus norvegicus,pappab;Danio rerio
255 ADCY5 AC5 adenylate cyclase 5 111 ADCY5_HUMAN mammal 3q21.1 1.23E+08 1.23E+08 -1   NM_183357 NP_899200 ####### CG43373;Drosophila melanogaster,Adcy5;Rattus norvegicus,Adcy5;Mus musculus,adcy5;Danio rerio
256 PPARGC1A PGC1 PGC1A PPARGC1 peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 10891 PRGC1_HUMAN mammal,upstream,downstream 4p15.1 23792021 23890077 -1   NM_013261 NP_037393 ####### Ppargc1a;Mus musculus,srl;Drosophila melanogaster,Ppargc1a;Rattus norvegicus,ppargc1a;Danio rerio
257 GPX4 PHGPx MCSP glutathione peroxidase 4 2879 GPX4_HUMAN putative 19p13.3 1103926 1106789 1 HS_GPX4 NM_002085 NP_002076 ####### gpx1;Schizosaccharomyces pombe,gpx4b;Danio rerio,Gpx4;Rattus norvegicus,gpx4a;Danio rerio,Gpx4;Mus musculus,GPX1;Saccharomyces cerevisiae,HYR1;Saccharomyces cerevisiae
258 UCP1 SLC25A7 UCP uncoupling protein 1 (mitochondrial, proton carrier) 7350 UCP1_HUMAN putative 4q28-q31 1.41E+08 1.41E+08 -1   NM_021833 NP_068605 ####### Ucp1;Mus musculus,Ucp1;Rattus norvegicus,ucp1;Danio rerio,DIC1;Saccharomyces cerevisiae,LOC100909612;Rattus norvegicus
259 FGF23   fibroblast growth factor 23 8074 FGF23_HUMAN downstream,putative 12p13.3 4368227 4379728 -1   NM_020638 NP_065689 ####### Fgf23;Mus musculus,Fgf23;Rattus norvegicus,fgf23;Danio rerio
260 EFEMP1 S1-5 FBLN3 MTLV DHRD FBNL EGF containing fibulin-like extracellular matrix protein 1 2202 FBLN3_HUMAN mammal 2p16 55865967 55924139 -1   NM_004105 NP_004096 ####### CG31999;Drosophila melanogaster,fbl-1;Caenorhabditis elegans,Efemp1;Mus musculus,Efemp1;Rattus norvegicus,EFEMP1 (1 of many);Danio rerio,EFEMP1 (1 of many);Danio rerio
261 ERCC4 RAD1 FANCQ XPF excision repair cross-complementation group 4 2072 XPF_HUMAN functional,putative 16p13.12 13920157 13952348 1   NM_005236 NP_005227 ####### rad16;Schizosaccharomyces pombe,AC117889.1;Rattus norvegicus,Ercc4;Rattus norvegicus,mei-9;Drosophila melanogaster,Ercc4;Mus musculus,xpf-1;Caenorhabditis elegans,ercc4;Danio rerio,RAD1;Saccharomyces cerevisiae
262 CETP BPIFF cholesteryl ester transfer protein, plasma 1071 CETP_HUMAN human_link 16q21 56961923 56983844 1   NM_000078 NP_000069 ####### cetp;Danio rerio
263 PPARG PPARG1 PPARG2 NR1C3 PPARgamma peroxisome proliferator-activated receptor gamma 5468 D2KUA6_HUMAN functional 3p25 12287850 12434356 1   NM_005037 NP_005028 ####### pparg;Danio rerio,Pparg;Mus musculus,Pparg;Rattus norvegicus,sex-1;Caenorhabditis elegans,nhr-38;Caenorhabditis elegans
264 AGTR1 AT1 AT2R1 AGTR1A AT2R1A HAT1R AG2S AT2R1B AT1B AGTR1B angiotensin II receptor, type 1 185 AGTR1_HUMAN mammal 3q24 1.49E+08 1.49E+08 1   NM_000685 NP_000676 ####### Agtr1a;Mus musculus,Agtr1b;Mus musculus,Agtr1a;Rattus norvegicus,Agtr1b;Rattus norvegicus,agtr1a;Danio rerio,agtr1b;Danio rerio
265 CISD2 Miner1 ERIS NAF-1 ZCD2 WFS2 CDGSH iron sulfur domain 2 493856 CISD2_HUMAN mammal 4q24 1.03E+08 1.03E+08 1   NM_001008388 NP_001008389 ####### Cisd2;Drosophila melanogaster,Cisd2;Mus musculus,Cisd2;Rattus norvegicus,cisd2;Danio rerio,cisd-1;Caenorhabditis elegans
266 EEF1E1 AIMP3 P18 eukaryotic translation elongation factor 1 epsilon 1 9521 MCA3_HUMAN mammal 6p24.3 8073360 8102595 -1   NM_001135650 NP_001129122 ####### CG30185;Drosophila melanogaster,eef1e1;Danio rerio
267 EPS8   epidermal growth factor receptor pathway substrate 8 2059 B4DX66_HUMAN mammal 12p12.3 15620141 15789576 -1   NM_004447 NP_004438 ####### Eps8;Mus musculus,aru;Drosophila melanogaster,CG8907;Drosophila melanogaster,eps-8;Caenorhabditis elegans,Eps8;Rattus norvegicus,eps8;Danio rerio
268 KCNA3 Kv1.3 MK3 HLK3 HPCN3 potassium channel, voltage gated shaker related subfamily A, member 3 3738 KCNA3_HUMAN mammal 1p13.3 1.11E+08 1.11E+08 -1   NM_002232 NP_002223 ####### Kcna3;Mus musculus,Kcna3;Rattus norvegicus,Sh;Drosophila melanogaster,shk-1;Caenorhabditis elegans,KCNA3;Danio rerio
269 SIRT7   sirtuin 7 51547 SIR7_HUMAN functional,putative 17q25 81911939 81918182 -1   NM_016538 NP_057622 ####### Sirt7;Drosophila melanogaster,Sirt7;Mus musculus,Sirt7;Rattus norvegicus,sirt7;Danio rerio
270 SLC13A1 NaSi-1 NAS1 solute carrier family 13 (sodium/sulfate symporter), member 1 6561 A4D0X1_HUMAN mammal,model 7q31.32 1.23E+08 1.23E+08 -1   NM_022444 NP_071889 ####### CG7309;Drosophila melanogaster,Indy;Drosophila melanogaster,Slc13a1;Mus musculus,Slc13a1;Rattus norvegicus,nac-3;Caenorhabditis elegans,nac-1;Caenorhabditis elegans,slc13a1;Danio rerio,CG33934;Drosophila melanogaster,Indy-2;Drosophila melanogaster
271 SOCS2 STATI2 SSI2 SOCS-2 SSI-2 CIS2 Cish2 suppressor of cytokine signaling 2 8835 SOCS2_HUMAN functional,upstream 12q 93569822 93576745 1   NM_003877 NP_003868 ####### AC124896.1;Rattus norvegicus,Gm9847;Mus musculus,Socs44A;Drosophila melanogaster,Socs2;Mus musculus,socs2;Danio rerio
273 TPP2   tripeptidyl peptidase II 7174 Q5VZU9_HUMAN mammal 13q32-q33 1.03E+08 1.03E+08 1   NM_003291 NP_003282 ####### tpp2;Schizosaccharomyces pombe,Tpp2;Mus musculus,TppII;Drosophila melanogaster,Tpp2;Rattus norvegicus,tpp-2;Caenorhabditis elegans,TPP2;Danio rerio
274 TP53BP1 53BP1 p202 TDRD30 tumor protein p53 binding protein 1 7158 F8VY86_HUMAN functional 15q15-q21 43407214 43493156 -1   NM_001141979 NP_001135451 ####### Trp53bp1;Mus musculus,Tp53bp1;Rattus norvegicus,tp53bp1;Danio rerio,hsr-9;Caenorhabditis elegans
275 SIRT3 SIR2L3 sirtuin 3 23410 E9PK80_HUMAN functional 11p15.5 215030 236362 -1   NM_001017524 NP_001017524 ####### Sirt3;Mus musculus,Sirt3;Rattus norvegicus,sirt3;Danio rerio,HST2;Saccharomyces cerevisiae
276 NCOR2 SMRT SMRTE TRAC-1 CTG26 TNRC14 nuclear receptor corepressor 2 9612 C9J0Q5_HUMAN mammal 12q24 1.24E+08 1.25E+08 -1   NM_001206654 NP_001193583 ####### Ncor2;Mus musculus,Smr;Drosophila melanogaster,gei-8;Caenorhabditis elegans,Ncor2;Rattus norvegicus,ncor2;Danio rerio,SNT1;Saccharomyces cerevisiae
277 SUN1 KIAA0810 FLJ12407 UNC84A Sad1 and UNC84 domain containing 1 23353 SUN1_HUMAN upstream 7p22.3 816615 874920 1   NM_001171944 NP_001165415 ####### koi;Drosophila melanogaster,Sun1;Mus musculus,unc-84;Caenorhabditis elegans,Sun1;Rattus norvegicus,sun1;Danio rerio
278 BAK1 BCL2L7 BAK CDN1 BCL2-antagonist/killer 1 578 BAK_HUMAN functional 6p21.3 33572546 33580293 -1 HS_BAK1 NM_001188 NP_001179 ####### Bak1;Mus musculus,Bak1;Rattus norvegicus
279 IGFBP2 IBP2 insulin-like growth factor binding protein 2, 36kDa 3485 C9JMY1_HUMAN mammal,functional 2q33-q34 2.17E+08 2.17E+08 1   NM_000597 NP_000588 ####### Igfbp2;Mus musculus,Igfbp2;Rattus norvegicus,igfbp2a;Danio rerio,igfbp2b;Danio rerio
280 PYCR1 P5C pyrroline-5-carboxylate reductase 1 5831 B4DMU0_HUMAN putative 17q25.3 81932386 81937257 -1   NM_153824 NP_722546 ####### Pycr1;Rattus norvegicus,P5cr-2;Drosophila melanogaster,M153.1;Caenorhabditis elegans,Pycr1;Mus musculus,pycr1a;Danio rerio,PRO3;Saccharomyces cerevisiae,pycr1b;Danio rerio,pycr1a;Danio rerio
281 TP73 P73 tumor protein p73 7161 C9J521_HUMAN functional,putative 1p36.3 3698046 3736201 1   NM_001204192 NP_001191121 ####### Trp73;Mus musculus,Tp73;Rattus norvegicus,tp73;Danio rerio
282 CNR1 CB1K5 CB-R CB1 CANN6 CB1A CNR cannabinoid receptor 1 (brain) 1268 CNR1_HUMAN putative 6q14-q15 88139865 88166048 -1   NM_001160226 NP_001153698 ####### Cnr1;Mus musculus,Cnr1;Rattus norvegicus,cnr1;Danio rerio
283 NFE2L2 NRF2 nuclear factor, erythroid 2-like 2 4780 NF2L2_HUMAN cell,upstream 2q31 1.77E+08 1.77E+08 -1   NM_001145413 NP_001138885 ####### Nfe2l2;Mus musculus,cnc;Drosophila melanogaster,Nfe2l2;Rattus norvegicus,nfe2l2a;Danio rerio
284 CDKN1A P21 CIP1 WAF1 SDI1 CAP20 p21CIP1 p21Cip1/Waf1 CDKN1 cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1026 CDN1A_HUMAN cell 6p21.2 36678679 36687339 1 HS_CDKN1A NM_000389 NP_000380 ####### Cdkn1a;Mus musculus,Cdkn1a;Rattus norvegicus,cdkn1a;Danio rerio
285 PDGFRA CD140a PDGFR2 platelet-derived growth factor receptor, alpha polypeptide 5156 PGFRA_HUMAN downstream 4q12 54229097 54298245 1   NM_006206 NP_006197 ####### Pdgfra;Mus musculus,Pdgfra;Rattus norvegicus,Pvr;Drosophila melanogaster,pdgfra;Danio rerio
286 PIK3CA PI3K phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 5290 PK3CA_HUMAN upstream 3q26.3 1.79E+08 1.79E+08 1   NM_006218 NP_006209 ####### Pik3ca;Mus musculus,Pi3K92E;Drosophila melanogaster,Pik3ca;Rattus norvegicus,pik3ca;Danio rerio,AABR07037536.1;Rattus norvegicus,VPS34;Saccharomyces cerevisiae
287 C1QA   complement component 1, q subcomponent, A chain 712 C1QA_HUMAN upstream 1p36.12 22636625 22639682 1   NM_015991 NP_057075 ####### C1qa;Mus musculus,C1qa;Rattus norvegicus,c1qa;Danio rerio
288 CDKN2B P15 MTS2 INK4B TP15 CDK4I p15INK4b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 1030 CDN2B_HUMAN cell 9p21 22002903 22009313 -1   NM_004936 NP_004927 ####### Cdkn2b;Mus musculus,Cdkn2b;Rattus norvegicus,cdkn2a/b;Danio rerio
289 EIF5A2   eukaryotic translation initiation factor 5A2 56648 IF5A2_HUMAN mammal 3q26.2 1.71E+08 1.71E+08 -1   NM_020390 NP_065123 ####### tif51b;Schizosaccharomyces pombe,eIF-5A;Drosophila melanogaster,Eif5a2;Mus musculus,Eif5a2;Rattus norvegicus,eif5a;Danio rerio,HYP2;Saccharomyces cerevisiae
290 MIF GIF GLIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 4282 I4AY87_HUMAN mammal 22q11.23 23894378 23895222 1 HS_MIF NM_002415 NP_002406 ####### AABR07016805.1;Rattus norvegicus,AABR07059201.1;Rattus norvegicus,LOC679748;Rattus norvegicus,RGD1559921;Rattus norvegicus,RGD1560513;Rattus norvegicus,RGD1565459;Rattus norvegicus,Mif;Mus musculus,LOC103694877;Rattus norvegicus,Mif;Rattus norvegicus,mif-1;Caenorhabditis elegans,mif;Danio rerio,LOC103694877;Rattus norvegicus,Mif;Rattus norvegicus
291 DGAT1 ARGP1 DGAT diacylglycerol O-acyltransferase 1 8694 DGAT1_HUMAN mammal 8q24.3 1.44E+08 1.44E+08 -1   NM_012079 NP_036211 ####### are1;Schizosaccharomyces pombe,Dgat1;Mus musculus,mdy;Drosophila melanogaster,Dgat1;Rattus norvegicus,mboa-2;Caenorhabditis elegans,dgat1a;Danio rerio,dgat1b;Danio rerio,ARE1;Saccharomyces cerevisiae,ARE2;Saccharomyces cerevisiae
292 MT1E MTD MT1 metallothionein 1E 4493 MT1E_HUMAN putative 16q13 56625673 56627113 1   NM_175617 NP_783316 16585059 Mt1;Mus musculus,Mt1;Rattus norvegicus
293 FGF21   fibroblast growth factor 21 26291 FGF21_HUMAN mammal 19q13.33 48756087 48758325 1   NM_019113 NP_061986 ####### Fgf21;Mus musculus,Fgf21;Rattus norvegicus,fgf21;Danio rerio
294 HTRA2 OMI PARK13 PRSS25 HtrA serine peptidase 2 27429 HTRA2_HUMAN mammal 2p12 74529405 74533556 1   NM_013247 NP_037379 ####### BX469935.1;Danio rerio,HTRA2;Danio rerio,si:dkey-112g5.11;Danio rerio,si:dkey-112g5.12;Danio rerio,si:dkey-19p15.4;Danio rerio,si:dkey-265c15.6;Danio rerio,si:dkey-33c12.10;Danio rerio,si:dkey-33c12.11;Danio rerio,si:dkey-33c12.12;Danio rerio,si:dkey-33c12.14;Danio rerio,si:dkey-84o3.3;Danio rerio,si:dkey-84o3.6;Danio rerio,HtrA2;Drosophila melanogaster,Htra2;Mus musculus,Htra2;Rattus norvegicus,si:dkey-10b15.8;Danio rerio,zgc:174193;Danio rerio,si:dkey-112g5.13;Danio rerio,si:dkey-112g5.14;Danio rerio,si:dkey-112g5.16;Danio rerio,si:dkey-84o3.7;Danio rerio,si:dkey-33c12.12;Danio rerio,si:dkey-112g5.13;Danio rerio,zgc:173425;Danio rerio,si:dkey-112g5.14;Danio rerio,zgc:174193;Danio rerio,si:dkey-84o3.7;Danio rerio
295 GSK3A   glycogen synthase kinase 3 alpha 2931 GSK3A_HUMAN mammal 19q13.2 42230186 42242584 -1   NM_019884 NP_063937 ####### gsk3;Schizosaccharomyces pombe,gsk3ab;Danio rerio,sgg;Drosophila melanogaster,gsk-3;Caenorhabditis elegans,gsk3aa;Danio rerio,MRK1;Saccharomyces cerevisiae,RIM11;Saccharomyces cerevisiae
296 NUDT1 MTH1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 4521 8ODP_HUMAN mammal 7p22 2242221 2251145 1   NM_002452 NP_002443 ####### Nudt1;Mus musculus,Nudt1;Rattus norvegicus,nudt1;Danio rerio
297 IKBKB IKK2 NFKBIKB IKK-beta IKKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 3551 IKKB_HUMAN mammal 8p11.2 42271302 42332653 1   NM_001190720 NP_001177649 ####### ird5;Drosophila melanogaster,Ikbkb;Mus musculus,Ikbkb;Rattus norvegicus,T07F12.4;Caenorhabditis elegans,ikbkb;Danio rerio,ATG1;Saccharomyces cerevisiae
298 SQSTM1 p62 p60 p62B A170 PDB3 OSIL sequestosome 1 8878 SQSTM_HUMAN putative 5q35 1.8E+08 1.8E+08 1   NM_001142298 NP_001135770 ####### Sqstm1;Mus musculus,Sqstm1;Rattus norvegicus,sqstm1;Danio rerio
299 CDK7 CAK1 CDKN7 MO15 STK1 CAK cyclin-dependent kinase 7 1022 CDK7_HUMAN mammal 5q12.1 69234795 69277430 1 HS_CDK7_2 NM_001799 NP_001790 ####### crk1;Schizosaccharomyces pombe,Cdk7;Mus musculus,Cdk7;Drosophila melanogaster,Cdk7;Rattus norvegicus,cdk-7;Caenorhabditis elegans,cdk7;Danio rerio,KIN28;Saccharomyces cerevisiae
300 GRN PCDGF PGRN CLN11 granulin 2896 GRN_HUMAN putative 17q21.32 44345086 44353106 1 HS_GRN NM_002087 NP_002078 ####### Grn;Mus musculus,Grn;Rattus norvegicus,pgrn-1;Caenorhabditis elegans,grnb;Danio rerio,grna;Danio rerio
301 SERPINE1 PAI PLANH1 PAI1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 5054 A0A024QYT5_HUMAN upstream 7q22.1 1.01E+08 1.01E+08 1   NM_000602 NP_000593 ####### Serpine1;Mus musculus,Serpine1;Rattus norvegicus,Spn28B;Drosophila melanogaster,Spn28Da;Drosophila melanogaster,Spn42Db;Drosophila melanogaster,Spn42Dc;Drosophila melanogaster,Spn42De;Drosophila melanogaster,Spn47C;Drosophila melanogaster,Spn43Ab;Drosophila melanogaster,Spn43Aa;Drosophila melanogaster,nec;Drosophila melanogaster,Spn55B;Drosophila melanogaster,Spn42Da;Drosophila melanogaster,Spn38F;Drosophila melanogaster,Spn28F;Drosophila melanogaster,Spn42Dd;Drosophila melanogaster,srp-1;Caenorhabditis elegans,srp-2;Caenorhabditis elegans,srp-3;Caenorhabditis elegans,srp-6;Caenorhabditis elegans,srp-7;Caenorhabditis elegans,srp-8;Caenorhabditis elegans,Spn28Db;Drosophila melanogaster,serpine1;Danio rerio
302 SPRTN DKFZP547N043 Spartan DVC1 C1orf124 SprT-like N-terminal domain 83932 A0A024R3U2_HUMAN putative 1q42-q43 2.31E+08 2.31E+08 1   NM_032018 NP_114407 ####### CG9203;Drosophila melanogaster,dvc-1;Caenorhabditis elegans,Sprtn;Mus musculus,Sprtn;Rattus norvegicus,SPRTN;Danio rerio
303 RICTOR MGC39830 AVO3 PIA KIAA1999 RPTOR independent companion of MTOR, complex 2 253260 RICTR_HUMAN functional,putative 5p13.1 38937921 39074408 -1   NM_152756 NP_689969 ####### ste16;Schizosaccharomyces pombe,rictor;Drosophila melanogaster,Rictor;Mus musculus,Rictor;Rattus norvegicus,rictora;Danio rerio,rictorb;Danio rerio,TSC11;Saccharomyces cerevisiae,rict-1;Caenorhabditis elegans
304 CTF1 CT-1 CT1 cardiotrophin 1 1489 CTF1_HUMAN putative 16p11.2 30896607 30903560 1   NM_001330 NP_001321 ####### Ctf1;Mus musculus,Ctf1;Rattus norvegicus
305 TRAP1 HSP75 HSP90L TNF receptor-associated protein 1 10131 Q53FS6_HUMAN functional,putative 16p13.3 3658037 3717597 -1 HS_TRAP1 NM_016292 NP_057376 ####### Trap1;Drosophila melanogaster,Trap1;Mus musculus,hsp-75;Caenorhabditis elegans,Trap1;Rattus norvegicus,trap1;Danio rerio,HSC82;Saccharomyces cerevisiae,HSP82;Saccharomyces cerevisiae
306 TRPV1 VR1 transient receptor potential cation channel subfamily V member 1 7442 TRPV1_HUMAN mammal 17p13.2 3565445 3609410 -1   NM_018727 NP_061197 ####### iav;Drosophila melanogaster,nan;Drosophila melanogaster,Trpv1;Rattus norvegicus,osm-9;Caenorhabditis elegans,ocr-4;Caenorhabditis elegans,ocr-1;Caenorhabditis elegans,ocr-2;Caenorhabditis elegans,ocr-3;Caenorhabditis elegans,Trpv1;Mus musculus,trpv1;Danio rerio
307 NFE2L1 NRF1 LCR-F1 FLJ00380 TCF11 nuclear factor, erythroid 2-like 1 4779 J9JIE5_HUMAN model,functional 17q21.3 48048324 48061545 1   NM_003204 NP_003195 ####### Nfe2l1;Mus musculus,cnc;Drosophila melanogaster,Nfe2l1;Rattus norvegicus,nfe2l1a;Danio rerio
308 IFNB1 IFB IFF IFNB IFN-beta Interferon beta 3456 IFNB_HUMAN mammal,cell 9p21.3 21077104 21077962 -1   NM_002176 NP_002167 ####### Ifnb1;Mus musculus,Ifnb1;Rattus norvegicus
309 GDF11 BMP11 BMP-11 growth differentiation factor 11 10220 A0A024RB20_HUMAN mammal,human_link 12q13.2 55743277 55757193 1   NM_005811 NP_005802 ####### Gdf11;Mus musculus,Gdf11;Rattus norvegicus,myo;Drosophila melanogaster,gdf11;Danio rerio
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