6.10.2016
presentation by 김건우
Why not in Korea?
He think 'mind' and 'accent' are the casues.
Koreans be afraid to ask question.
He thought that accent affects mind.
'mindset'
Investment on the Basic science
accent can induce racism. asian accent can make the theories not understandable.
Nobel Prize It's all about contribution
Epigenomics
Epi(outside)
Reversible DNA and Histone modification and RNA interference -> causing chage of gene expression
histone acetylation/methylation
Diseases related to the histone modification
How do we study?
1. Bisulfite sequencing : treat cytosine with bisulfite changing it to be uracil ! but leaves methylcytosine unaffected. see with cytosine is changed by sequencing the DNA before and after the bisulfite treatment
2. Nonmethylated specific PCR
Proteomic
Phosphorylation is the switch of proteins. and it requires energy
Proteins - a helix + b sheet for stable structure + coils to bind others
Coils are to bind and to attack.
Glycosylation
Sulfation
How?
1. 2D SDS PAGE
2. Mass spectrometer