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3. Pick 5 protein sequences and predict their secondary structures using available prediction programs

Revision as of 11:15, 15 June 2016 by imported>Jaehyeok Shin
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)

I used Jpred 4 program http://www.compbio.dundee.ac.uk/jpred4/index.html

'H' - Helix, 'E' - Extended, 'B' - Buried, '-' - other types

DSCR1(RCAN1) - Down Syndrome Critical Region 1, Regulator of Calcineurin 1


<span style="font-family:courier new,courier,monospace"><code>MVYAKFESLFRTYDKDITFQYFKSFKRVRINFSNPFSAADARLQLHKTEFLGKEMKLYFAQTLHIGSSHLAPPNPDKQFLISPPASPPVGWKQVEDATPVINYDLLYAISKLGPGEKYELHAATDTTPSVVVHVCESDQEKEEEEEMERMRRPKPKIIQTRRPEYTPIHLS
-HHHHHHHHHH-----EEEEE-----EEEEEE--HHHHHHHHHHH--------EEEEEE-------------------------------EEE---------HHHHHHHHH-------EE--------EEEEEE---------------------E---------------</code></span>

FMRP - Fragile X syndrome Mental Retardation Protein

<span style="font-family:arial,helvetica,sans-serif"><code>MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDINESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKPATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKRAHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGANIQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKNGKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEEKKHLDIKENSTHFSQPNSTKVQRVLVASSVVAGESQKPELKAWQGMVPFVFVGTKDSIANATVLLDYHLNYLKEVDQLRLERLQIDEQLRQIGASSRPPPNRTDKEKSYVTDDGQGMGRGSRPYRNRGHGRRGPGYTSGTNSEASNASETESDHRDELSDWSLAPTEEERESFLRRGDGRRRGGGGRGQGGRGRGGGFKGNDDHSRTDNRPRNPREAKGRTTDGSLQIRVDCNNERSVHTKTLQNTSSEGSRLRTGKDRNQKKEKPDSVDGQQPLVNGVP
---EEEEEE-----EEEEEEEEE---EEEEEE-------------------------------EEEEEE----------EEEEEEEE----EEEEEE-------EEEEE----------------EEEEEEE--HHHHHHHH-HHHHHHHHH---EEEEEE-----EEEEEE-----EEEEEH-HEEE----HHHHHHHHHHHHHHHHHHHHHHH----EEEEE-----HHHH------HHHHHHH----EEEE------EEEEEE--HHHHHHHHHHHHHHHEEEEE------EEE----HHHHHHH----EEEEEE-------------------HHHHHHHHHHHHHHHHHHH------EEE----------------------------------EEEEEEE--HHHHHHHHHHHHHHHHHHH-HHHHHEE-------------------EE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------</code></span>

Death associated protein kinase 3

<span style="font-family:arial,helvetica,sans-serif"><code>MSTFRQEDVEDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSNTSELAKDFIRRLLVKDPKRRMTIAQSLEHSWIKAIRRRNVRGEDSGRKPERRRLKTTRLKEYTIKSHSSLPPNNSYADFERFSKVLEEAAAAEEGLRELQRSRRLCHEDVEALAAIYEEKEAWYREESDSLGQDLRRLRQELLKTEALKRQAQEEAKGALLGTSGLKRRFSRLENRYEALAKQVASEMRFVQDLVRALEQEKLQGVECGLR
------------EEEEEEEEE---EEEEEEEE----EEEEEEEEE--------HHHHHHHHHHHHHHHHH-----EEEEEEEE----EEEEEEEE----HHHHHHHH-----HHHHHHHHHHHHHHHHHHHH---EEE-----EEEE---------EEEEE---EEEE----EEEEE------HHHHHH----------HHHHHHHHHHHHH---------HHHHHHHHH---------------HHHHHHHHHHH---------HHHHHH---------------------------------------------------------------------HHHHHH------------HHHH-----------HHHHHHHHH-----HHHHHH---------------HHHHHHHHHHHHHHHHHHH---HHHHHHHHHHHHH-----------</code></span>

Calcineurin

<span style="font-family:arial,helvetica,sans-serif"><code>MGVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGAAQMSLGQRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLNLE
--EEEEEEEE-----------EEEEEEEEEE----EEEE------EEEEEE----HHHHHHHHH-------EEEEEE--------------------EEEEEEEEE--</code></span>

Fc region of Immunoglobluin G

<code>MDWTWRFLFVVAAATGVQSQMQVVQSGAEVKKPGSSVTVSCKASGGTFSNYAISWVRQAPGQGLEWMGGIIPLFGTPTYSQNFQGRVTITADKSTSTAHMELISLRSEDTAVYYCATDRYRQANFDRARVGWFDPWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
--HHHHHHHHHHHH------EEEEE----EEE----EEEEEEE--------EEEEEEE------EEEEEE----------------EEEE-------EEEEE---------EEEE------------------EE-----EEEE------------------------EEEEEEE--------EEEE-----EE--EEEEE---------EEEEEE---------EEEEEEE-------EEE----------------------------------------------EEEEEE-------EEEEEE---------------------EEEEEEEE----------EEEEEE-------EEEEEEEE--------EEEEE------------EEEEEEE------EEEEEE--------------------EEEEEEEEEE---------EEEEEEEE------EEEEEEE-----</code>