Difference between revisions of "KSH 0611 Review Epigenetic modifications regulate gene expression"

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imported>Seung-hoon Kim
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<h2>Epigenetic&nbsp; modifications are crucial for packaging and interpreting the genome</h2>
 
  
 
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<h3>The patterns of epigenetic modifications&nbsp; can serve as</h3>
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<h2>Why is it important ? &gt;&gt;&gt; Epigenetic&nbsp; modifications regulate gene activity and expression during development and differentiation, or in response to environmental stimuli</h2>
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<h2>Epigenetics is considered a bridge between genotype and phenotype</h2>
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<h2>Explain how cells carrying identical DNA differentiate into different cell types &gt;&gt;&gt; Epigenetics</h2>
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<h2>Epigenome - global analyses of epigenetic markers across the entire genome</h2>
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<h2>Chromatin - Histone protein / DNA complex&nbsp;in eukaryotic cells</h2>
  
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<li>Epigenetic markers to represent gene activity and expression</li>
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<li>Epigenetic markers to represent chromatin state</li>
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Revision as of 01:26, 11 June 2016

 Epigenetics

Definition : Heritable changes in gene activity and expression that occur without alteration in DNA sequence

Two well-known epigenetic modifications

  1. Chemical modification to the cytosine residues of DNA (DNA methylation)
  2. Histone modification

Why is it important ? >>> Epigenetic  modifications regulate gene activity and expression during development and differentiation, or in response to environmental stimuli

Epigenetics is considered a bridge between genotype and phenotype

Explain how cells carrying identical DNA differentiate into different cell types >>> Epigenetics

Epigenome - global analyses of epigenetic markers across the entire genome

Chromatin - Histone protein / DNA complex in eukaryotic cells

 

 

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