Difference between revisions of "5/27 ask"
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imported>S (Created page with "<p>Genetics : study about genome variation and its effect</p> <p>presentation summary :</p> <p>There are hypothesis-driven and hypothesis-generating(data-driven) approaches.</p...") |
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<p>First, it does not tell us the causality. It tells us the correlation. So we need to find the causal gene.</p> | <p>First, it does not tell us the causality. It tells us the correlation. So we need to find the causal gene.</p> | ||
| − | <p>Second, the gene does not tell everything.</p> | + | <p>Second, the gene does not tell everything. Actually, protein structures are well preserved than DNA sequence.</p> |
<p>To solve these promblems, we have to research multiple types of data such as protein, mRNA and metabolite</p> | <p>To solve these promblems, we have to research multiple types of data such as protein, mRNA and metabolite</p> | ||
Revision as of 00:01, 30 May 2016
Genetics : study about genome variation and its effect
presentation summary :
There are hypothesis-driven and hypothesis-generating(data-driven) approaches.
Both approaches is useful and compensate each other.
However, in my opinion, there are limitations.
First, it does not tell us the causality. It tells us the correlation. So we need to find the causal gene.
Second, the gene does not tell everything. Actually, protein structures are well preserved than DNA sequence.
To solve these promblems, we have to research multiple types of data such as protein, mRNA and metabolite
and then integrate all together to interpret the biological system.
