Difference between revisions of "Genomics for JS"

From Biolecture.org
imported>Jungsu Shin
imported>Jungsu Shin
Line 1: Line 1:
 +
<p>Genomics database by Mike</p>
 +
 
<p>SNPedia : (www.snpedia.com)</p>
 
<p>SNPedia : (www.snpedia.com)</p>
  
Line 18: Line 20:
 
<p>&nbsp;</p>
 
<p>&nbsp;</p>
  
<p>Research approches by presentation.</p>
+
<p>Research approches by presentation</p>
  
 
<ul>
 
<ul>
Line 26: Line 28:
 
</ul>
 
</ul>
  
<p style="margin-left: 40px;">-&gt; family linkage study +&nbsp;genome wide association study =&nbsp;candidate gene association study (hypothesis -&gt; target gene search, specific&nbsp;gene research possibly, but unpredictable&nbsp;gene reasearch&nbsp;impossibly)</p>
+
<p style="margin-left:40px">-&gt; family linkage study +&nbsp;genome wide association study =&nbsp;candidate gene association study (hypothesis -&gt; target gene search, specific&nbsp;gene research possibly, but unpredictable&nbsp;gene reasearch&nbsp;impossibly)</p>
 +
 
 +
<p style="margin-left:40px">-&gt; limitation : it is remained to examine functional implications and identify the&nbsp;casual gene, gene doesn&#39;t&nbsp;tell about everything.</p>
 +
 
 +
<p>&nbsp;</p>
  
<p style="margin-left: 40px;">-&gt; limitation : it is remained to examine functional implications and identify the&nbsp;casual gene, gene doesn&#39;t&nbsp;tell about everything.</p>
+
<p>Genomics in the lecture</p>
 +
 
 +
<ul>
 +
<li>Geno + Envriro = Pheno</li>
 +
<li>Solution : exact data,&nbsp;principles, laws, algorithms, etc..</li>
 +
<li>Typing&nbsp;: Sequencing -&gt; Imaging</li>
 +
<li>For example :&nbsp;High altitude adaptation, baleen whale -&gt; hypothesis-driven</li>
 +
</ul>

Revision as of 15:19, 27 May 2016

Genomics database by Mike

SNPedia : (www.snpedia.com)

For examples..

Promethease : (www,promethease.com)

For example..

 

Research approches by presentation

  • hypothesis-driven : candidate gene studies
  • data-driven (hypothesis-generating) : familiy linakge studies, genome wide association studies
  • which one is better? nothing is better.

-> family linkage study + genome wide association study = candidate gene association study (hypothesis -> target gene search, specific gene research possibly, but unpredictable gene reasearch impossibly)

-> limitation : it is remained to examine functional implications and identify the casual gene, gene doesn't tell about everything.

 

Genomics in the lecture

  • Geno + Envriro = Pheno
  • Solution : exact data, principles, laws, algorithms, etc..
  • Typing : Sequencing -> Imaging
  • For example : High altitude adaptation, baleen whale -> hypothesis-driven