Seunggyu Jeon.

 Genomics

 What is genomics?

Genomics is a analysis of the function and structure of genes. and by telling the differences, we can find out genetic regulation or expression related with biologicl phenomenon.

 Interesting terminologies and subject

 We can simply tell the difference between micro and macro.

 Micro- : Things that we can't see.

 Macro- : Things that we can see.

 Ome-

- This is the term to present something complex

 Algorithm  

It's not just one single, but multiple complex. And there are step by step operations.

 How do we solve some problems?

 - We firstly need to gather data. And analyze them.

 Who analyzes statistic problems?

- Inteesting thing is there is just two things that can ananlze statistics in universe.:Natural neuronal network(Brain)  and artificial neuronal network(Computer).

I think somehow, alien may be added as new catalog.

 PSG

- For example, in tiger, there are tiger's variants. They are kinda prior genes, compared to other species

 Is there gene which can predict car accident?

 - Maybe yes, For example, genes related with eye sight or mental desease can tell us probability of car accident.

In aspect of this logic,  Ithink from analyzing genes, talant of each person can be predicted in the young. For example, if muscle gene for swimming is overexpressed, he will be good at swimming later.

 Interesting point in this class is that

 Can we obtain PSG s from other species? If we can, human being can live more than 100 years like whale. And we can eat law matrial like tiger.

To obtain some super phenotype or cure desease, genomics is important.

 Transcriptomics

 What is transcriptomics?

The transcriptome is the set of all RNA molecules, including mRNA, rRNA,tRNA, and other non-coding RNA sequence in one cell or a population of cell.  We can simply say this concept is that RNA is more important than DNA and protein.

 

 

 Protemics

 Interesting terminologies and subject

 Ligand

- Anything with which proteins interect or bind.

Protein in water? Protein in oil?

Sequnce identity

 

Major mechanisms in terms of protein are

 - Expressions

 - Degradation

  - Interaction.

 How do we find out all of proteins(around 10,000 type) in the cell?

- Difficult point of this is that it's hard to detect certain  small amount of protein.

So, my idea is ampifying like PCR for DNA. If we can ampify proteins, all of proteins in one cell could be identified.

Then, how can we amplify certain protein? Over express genes related with translation. Over translation would make more proteins than before.

Or bloking genes and organelle related with potein degradation would give high amount of proteins.

But it would kill cell because of abnormal amount of poteins. We need to think antoehr idea.

 

 Epigenomics

 What is epigenomics?

Epigenetics is the study of cellular and physiological trait variations that are not caused by changes in the DNA sequence. Simply, this is the concept saying histon code is more important than genetic code.

 Interesting terminologies and subject

 Yeast - Sngle cell eukaryote.

 Canceromics and Geromics

 What is canceromic and geromics?

Oncogenomics is a study that applies high throughput technologies to characterize genes associated with cancer.

Simply, this is ananalisis of genes related with cancer.

 

 Geromics is a study that applies high throughput technologies to characterize genes associated with aging.

Simply, this is ananalisis of genes related with aging.

 Interesting terminologies and subject

Problems of cancer and aging

 Cancer : Probleim with non-dying celsl.

 Aging : Problem with dying cells.

Both of them is because of unbalance betwenn dying cells and living cells.

 

There are some specific animanl which doesn't die or get cancer.

 We don't know yet, what is the difference between this animal's gene and human's.

If we find out this difference, we expect to screat of surviing and not having cancer.

 

Calorie reduction

 Intereting thing is that more calore reduction induce organism to die early.

There is some statistical data which is that athlete dies faster than ordinary person.

 Thinking

What is lecture and presentation?

'Lecture'
Lecture is delivery of what some people know efficiently. And the point of lecture is listener can ask some question about topic of lecture and right after that, lecture giver can answer. That means the difference lecture and internet material is communication.

'Presentation'
Presentation is one of efficient ways to delivery  information during lecture.  It is powerful visual delivery material to give information. Durimg presentation, we can use words, image,vedio, etc. Any kinds of visual things can be used to understand listener. With this visual material, we should give talk or lecture efficiently.

What is reality?

'Reality'
This term is needed to tell the difference that something is exist or not. But, sometimes it is very ambiguous. What is exect 'real'? The criteria is important whether is real or not. I will brifely show some kind of criteria to be able to say 'real'. First

Is Darwin evolutionary theory correct?

I don't agree with Darwin's theory of evolution. Firstly let's check basic concept of this theory briefly.

 

Darwin's Theory of Evolution

He said complex creatures evolve from more simplistic ancestors naturally over time. In a nutshell, as random genetic mutations occur within an organism's genetic code, the beneficial mutations are preserved because they are easier to survive. This is called "natural selection." These beneficial mutations are passed on to the next generation. Over time, beneficial mutations accumulate and the result is an entirely different organism. And then, he emphasized organisms reproduce many offsprings for them to survive. It means all offsprings can not survive against the enviorment. The one which has superior gene survives.

 

What I want to say is that the concept of evolution should be separated to human being and other organisms. Let me talk about the differences between human being and other organisms in the aspect evolution.

First, Human can think but other organism can't. In Dawin's theory of evolution, other organisms reproduce offsprings as much as possible for them to survive. But human being is different. Nowadays, birth rate is very low. They usually give a birth to two or just one baby because of many problems of society. Although human has the biological ability to reproduce many offsprings, they do not reproduce as much as possible. It's because human can think. Animal has a brain. But animal can not control themselves. What I mean by that is human can regulate showing or solving desire such as sleep, sex, or eating. But in animal system, there is no regulation. So, animals give a birth their offspring without any fear. In animal system, they should have prior gene to survive against predator or environment Then, How do human preserve generation without reproducing many offsprings? When human is young, they can learn many what is dangerous in advance such as which species are dangerous or whichever dangerous situation. It can be possible people can think, have the ability to teach someone, learn and remember what they learned. Human who has some bad genes absolutely relate with survival. Finally, the way to survive in environment is totally different.

And let's see again how human and animal are different to against environment. For example, when it is cold, birds fly to the warm region. How about human? Even though season or weather is changed, human live where they already lived. They make something like cloths, air conditional, etc and use them to survive the environment. The surviving style is totally different. Therefore Dawin's theory is applied.

Before human exist, Dawin's theory, especially natural selection from many offsprings. is adapted. Many organisms have evolved and finally human being is created from other animal. I guess human being is final stage of Dawin's evolution. From human, we can not explain evolution by Dawin's theory. We need to think other concept of evolution for human.