Difference between revisions of "3. Pick 5 protein sequences and predict their secondary structures using available prediction programs"
From Biolecture.org
imported>Jaehyeok Shin |
imported>Jaehyeok Shin |
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− | <p>I used Jpred 4 program <a href="http://www.compbio.dundee.ac.uk/jpred4/index.html">http://www.compbio.dundee.ac.uk/jpred4/index.html</a></p> | + | <p><span style="font-family:arial,helvetica,sans-serif">I used Jpred 4 program <a href="http://www.compbio.dundee.ac.uk/jpred4/index.html">http://www.compbio.dundee.ac.uk/jpred4/index.html</a></span></p> |
− | <p>'H' - Helix, 'E' - Extended, 'B' - Buried, '-' - other types</p> | + | <p><span style="font-family:arial,helvetica,sans-serif">'H' - Helix, 'E' - Extended, 'B' - Buried, '-' - other types</span></p> |
− | <p>DSCR1(RCAN1) - Down Syndrome Critical Region 1, Regulator of Calcineurin 1</p> | + | <p><span style="font-family:arial,helvetica,sans-serif">DSCR1(RCAN1) - Down Syndrome Critical Region 1, Regulator of Calcineurin 1</span></p> |
<hr /> | <hr /> | ||
<pre> | <pre> | ||
− | <code>MVYAKFESLFRTYDKDITFQYFKSFKRVRINFSNPFSAADARLQLHKTEFLGKEMKLYFAQTLHIGSSHLAPPNPDKQFLISPPASPPVGWKQVEDATPVINYDLLYAISKLGPGEKYELHAATDTTPSVVVHVCESDQEKEEEEEMERMRRPKPKIIQTRRPEYTPIHLS | + | <span style="font-family:courier new,courier,monospace"><code>MVYAKFESLFRTYDKDITFQYFKSFKRVRINFSNPFSAADARLQLHKTEFLGKEMKLYFAQTLHIGSSHLAPPNPDKQFLISPPASPPVGWKQVEDATPVINYDLLYAISKLGPGEKYELHAATDTTPSVVVHVCESDQEKEEEEEMERMRRPKPKIIQTRRPEYTPIHLS |
− | -HHHHHHHHHH-----EEEEE-----EEEEEE--HHHHHHHHHHH--------EEEEEE-------------------------------EEE---------HHHHHHHHH-------EE--------EEEEEE---------------------E---------------</code></pre> | + | -HHHHHHHHHH-----EEEEE-----EEEEEE--HHHHHHHHHHH--------EEEEEE-------------------------------EEE---------HHHHHHHHH-------EE--------EEEEEE---------------------E---------------</code></span></pre> |
<hr /> | <hr /> | ||
− | <p>FMRP - Fragile X syndrome Mental Retardation Protein</p> | + | <p><span style="font-family:arial,helvetica,sans-serif">FMRP - Fragile X syndrome Mental Retardation Protein</span></p> |
<pre> | <pre> | ||
− | <code>MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDINESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKPATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKRAHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGANIQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKNGKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEEKKHLDIKENSTHFSQPNSTKVQRVLVASSVVAGESQKPELKAWQGMVPFVFVGTKDSIANATVLLDYHLNYLKEVDQLRLERLQIDEQLRQIGASSRPPPNRTDKEKSYVTDDGQGMGRGSRPYRNRGHGRRGPGYTSGTNSEASNASETESDHRDELSDWSLAPTEEERESFLRRGDGRRRGGGGRGQGGRGRGGGFKGNDDHSRTDNRPRNPREAKGRTTDGSLQIRVDCNNERSVHTKTLQNTSSEGSRLRTGKDRNQKKEKPDSVDGQQPLVNGVP | + | <span style="font-family:arial,helvetica,sans-serif"><code>MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDINESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKPATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKRAHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGANIQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKNGKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEEKKHLDIKENSTHFSQPNSTKVQRVLVASSVVAGESQKPELKAWQGMVPFVFVGTKDSIANATVLLDYHLNYLKEVDQLRLERLQIDEQLRQIGASSRPPPNRTDKEKSYVTDDGQGMGRGSRPYRNRGHGRRGPGYTSGTNSEASNASETESDHRDELSDWSLAPTEEERESFLRRGDGRRRGGGGRGQGGRGRGGGFKGNDDHSRTDNRPRNPREAKGRTTDGSLQIRVDCNNERSVHTKTLQNTSSEGSRLRTGKDRNQKKEKPDSVDGQQPLVNGVP |
− | ---EEEEEE-----EEEEEEEEE---EEEEEE-------------------------------EEEEEE----------EEEEEEEE----EEEEEE-------EEEEE----------------EEEEEEE--HHHHHHHH-HHHHHHHHH---EEEEEE-----EEEEEE-----EEEEEH-HEEE----HHHHHHHHHHHHHHHHHHHHHHH----EEEEE-----HHHH------HHHHHHH----EEEE------EEEEEE--HHHHHHHHHHHHHHHEEEEE------EEE----HHHHHHH----EEEEEE-------------------HHHHHHHHHHHHHHHHHHH------EEE----------------------------------EEEEEEE--HHHHHHHHHHHHHHHHHHH-HHHHHEE-------------------EE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------</code></pre> | + | ---EEEEEE-----EEEEEEEEE---EEEEEE-------------------------------EEEEEE----------EEEEEEEE----EEEEEE-------EEEEE----------------EEEEEEE--HHHHHHHH-HHHHHHHHH---EEEEEE-----EEEEEE-----EEEEEH-HEEE----HHHHHHHHHHHHHHHHHHHHHHH----EEEEE-----HHHH------HHHHHHH----EEEE------EEEEEE--HHHHHHHHHHHHHHHEEEEE------EEE----HHHHHHH----EEEEEE-------------------HHHHHHHHHHHHHHHHHHH------EEE----------------------------------EEEEEEE--HHHHHHHHHHHHHHHHHHH-HHHHHEE-------------------EE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------</code></span></pre> |
<hr /> | <hr /> | ||
− | <p>Death associated protein kinase 3</p> | + | <p><span style="font-family:arial,helvetica,sans-serif">Death associated protein kinase 3</span></p> |
<pre> | <pre> | ||
− | <code>MSTFRQEDVEDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSNTSELAKDFIRRLLVKDPKRRMTIAQSLEHSWIKAIRRRNVRGEDSGRKPERRRLKTTRLKEYTIKSHSSLPPNNSYADFERFSKVLEEAAAAEEGLRELQRSRRLCHEDVEALAAIYEEKEAWYREESDSLGQDLRRLRQELLKTEALKRQAQEEAKGALLGTSGLKRRFSRLENRYEALAKQVASEMRFVQDLVRALEQEKLQGVECGLR | + | <span style="font-family:arial,helvetica,sans-serif"><code>MSTFRQEDVEDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSNTSELAKDFIRRLLVKDPKRRMTIAQSLEHSWIKAIRRRNVRGEDSGRKPERRRLKTTRLKEYTIKSHSSLPPNNSYADFERFSKVLEEAAAAEEGLRELQRSRRLCHEDVEALAAIYEEKEAWYREESDSLGQDLRRLRQELLKTEALKRQAQEEAKGALLGTSGLKRRFSRLENRYEALAKQVASEMRFVQDLVRALEQEKLQGVECGLR |
− | ------------EEEEEEEEE---EEEEEEEE----EEEEEEEEE--------HHHHHHHHHHHHHHHHH-----EEEEEEEE----EEEEEEEE----HHHHHHHH-----HHHHHHHHHHHHHHHHHHHH---EEE-----EEEE---------EEEEE---EEEE----EEEEE------HHHHHH----------HHHHHHHHHHHHH---------HHHHHHHHH---------------HHHHHHHHHHH---------HHHHHH---------------------------------------------------------------------HHHHHH------------HHHH-----------HHHHHHHHH-----HHHHHH---------------HHHHHHHHHHHHHHHHHHH---HHHHHHHHHHHHH-----------</code></pre> | + | ------------EEEEEEEEE---EEEEEEEE----EEEEEEEEE--------HHHHHHHHHHHHHHHHH-----EEEEEEEE----EEEEEEEE----HHHHHHHH-----HHHHHHHHHHHHHHHHHHHH---EEE-----EEEE---------EEEEE---EEEE----EEEEE------HHHHHH----------HHHHHHHHHHHHH---------HHHHHHHHH---------------HHHHHHHHHHH---------HHHHHH---------------------------------------------------------------------HHHHHH------------HHHH-----------HHHHHHHHH-----HHHHHH---------------HHHHHHHHHHHHHHHHHHH---HHHHHHHHHHHHH-----------</code></span></pre> |
<hr /> | <hr /> | ||
− | <p>Calcineurin</p> | + | <p><span style="font-family:arial,helvetica,sans-serif">Calcineurin</span></p> |
<pre> | <pre> | ||
− | <code>MGVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGAAQMSLGQRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLNLE | + | <span style="font-family:arial,helvetica,sans-serif"><code>MGVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGAAQMSLGQRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLNLE |
− | --EEEEEEEE-----------EEEEEEEEEE----EEEE------EEEEEE----HHHHHHHHH-------EEEEEE--------------------EEEEEEEEE--</code></pre> | + | --EEEEEEEE-----------EEEEEEEEEE----EEEE------EEEEEE----HHHHHHHHH-------EEEEEE--------------------EEEEEEEEE--</code></span></pre> |
<hr /> | <hr /> | ||
− | <p>Fc region of Immunoglobluin G</p> | + | <p><span style="font-family:arial,helvetica,sans-serif">Fc region of Immunoglobluin G</span></p> |
− | < | + | <pre> |
+ | <code>MDWTWRFLFVVAAATGVQSQMQVVQSGAEVKKPGSSVTVSCKASGGTFSNYAISWVRQAPGQGLEWMGGIIPLFGTPTYSQNFQGRVTITADKSTSTAHMELISLRSEDTAVYYCATDRYRQANFDRARVGWFDPWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK | ||
+ | --HHHHHHHHHHHH------EEEEE----EEE----EEEEEEE--------EEEEEEE------EEEEEE----------------EEEE-------EEEEE---------EEEE------------------EE-----EEEE------------------------EEEEEEE--------EEEE-----EE--EEEEE---------EEEEEE---------EEEEEEE-------EEE----------------------------------------------EEEEEE-------EEEEEE---------------------EEEEEEEE----------EEEEEE-------EEEEEEEE--------EEEEE------------EEEEEEE------EEEEEE--------------------EEEEEEEEEE---------EEEEEEEE------EEEEEEE-----</code></pre> | ||
− | <p> </p> | + | <p><span style="font-family:arial,helvetica,sans-serif"> </span></p> |
Latest revision as of 11:15, 15 June 2016
I used Jpred 4 program http://www.compbio.dundee.ac.uk/jpred4/index.html
'H' - Helix, 'E' - Extended, 'B' - Buried, '-' - other types
DSCR1(RCAN1) - Down Syndrome Critical Region 1, Regulator of Calcineurin 1
<span style="font-family:courier new,courier,monospace"><code>MVYAKFESLFRTYDKDITFQYFKSFKRVRINFSNPFSAADARLQLHKTEFLGKEMKLYFAQTLHIGSSHLAPPNPDKQFLISPPASPPVGWKQVEDATPVINYDLLYAISKLGPGEKYELHAATDTTPSVVVHVCESDQEKEEEEEMERMRRPKPKIIQTRRPEYTPIHLS -HHHHHHHHHH-----EEEEE-----EEEEEE--HHHHHHHHHHH--------EEEEEE-------------------------------EEE---------HHHHHHHHH-------EE--------EEEEEE---------------------E---------------</code></span>
FMRP - Fragile X syndrome Mental Retardation Protein
<span style="font-family:arial,helvetica,sans-serif"><code>MEELVVEVRGSNGAFYKAFVKDVHEDSITVAFENNWQPDRQIPFHDVRFPPPVGYNKDINESDEVEVYSRANEKEPCCWWLAKVRMIKGEFYVIEYAACDATYNEIVTIERLRSVNPNKPATKDTFHKIKLDVPEDLRQMCAKEAAHKDFKKAVGAFSVTYDPENYQLVILSINEVTSKRAHMLIDMHFRSLRTKLSLIMRNEEASKQLESSRQLASRFHEQFIVREDLMGLAIGTHGANIQQARKVPGVTAIDLDEDTCTFHIYGEDQDAVKKARSFLEFAEDVIQVPRNLVGKVIGKNGKLIQEIVDKSGVVRVRIEAENEKNVPQEEEIMPPNSLPSNNSRVGPNAPEEKKHLDIKENSTHFSQPNSTKVQRVLVASSVVAGESQKPELKAWQGMVPFVFVGTKDSIANATVLLDYHLNYLKEVDQLRLERLQIDEQLRQIGASSRPPPNRTDKEKSYVTDDGQGMGRGSRPYRNRGHGRRGPGYTSGTNSEASNASETESDHRDELSDWSLAPTEEERESFLRRGDGRRRGGGGRGQGGRGRGGGFKGNDDHSRTDNRPRNPREAKGRTTDGSLQIRVDCNNERSVHTKTLQNTSSEGSRLRTGKDRNQKKEKPDSVDGQQPLVNGVP ---EEEEEE-----EEEEEEEEE---EEEEEE-------------------------------EEEEEE----------EEEEEEEE----EEEEEE-------EEEEE----------------EEEEEEE--HHHHHHHH-HHHHHHHHH---EEEEEE-----EEEEEE-----EEEEEH-HEEE----HHHHHHHHHHHHHHHHHHHHHHH----EEEEE-----HHHH------HHHHHHH----EEEE------EEEEEE--HHHHHHHHHHHHHHHEEEEE------EEE----HHHHHHH----EEEEEE-------------------HHHHHHHHHHHHHHHHHHH------EEE----------------------------------EEEEEEE--HHHHHHHHHHHHHHHHHHH-HHHHHEE-------------------EE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------</code></span>
Death associated protein kinase 3
<span style="font-family:arial,helvetica,sans-serif"><code>MSTFRQEDVEDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILREIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSNTSELAKDFIRRLLVKDPKRRMTIAQSLEHSWIKAIRRRNVRGEDSGRKPERRRLKTTRLKEYTIKSHSSLPPNNSYADFERFSKVLEEAAAAEEGLRELQRSRRLCHEDVEALAAIYEEKEAWYREESDSLGQDLRRLRQELLKTEALKRQAQEEAKGALLGTSGLKRRFSRLENRYEALAKQVASEMRFVQDLVRALEQEKLQGVECGLR ------------EEEEEEEEE---EEEEEEEE----EEEEEEEEE--------HHHHHHHHHHHHHHHHH-----EEEEEEEE----EEEEEEEE----HHHHHHHH-----HHHHHHHHHHHHHHHHHHHH---EEE-----EEEE---------EEEEE---EEEE----EEEEE------HHHHHH----------HHHHHHHHHHHHH---------HHHHHHHHH---------------HHHHHHHHHHH---------HHHHHH---------------------------------------------------------------------HHHHHH------------HHHH-----------HHHHHHHHH-----HHHHHH---------------HHHHHHHHHHHHHHHHHHH---HHHHHHHHHHHHH-----------</code></span>
Calcineurin
<span style="font-family:arial,helvetica,sans-serif"><code>MGVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGAAQMSLGQRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLNLE --EEEEEEEE-----------EEEEEEEEEE----EEEE------EEEEEE----HHHHHHHHH-------EEEEEE--------------------EEEEEEEEE--</code></span>
Fc region of Immunoglobluin G
<code>MDWTWRFLFVVAAATGVQSQMQVVQSGAEVKKPGSSVTVSCKASGGTFSNYAISWVRQAPGQGLEWMGGIIPLFGTPTYSQNFQGRVTITADKSTSTAHMELISLRSEDTAVYYCATDRYRQANFDRARVGWFDPWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK --HHHHHHHHHHHH------EEEEE----EEE----EEEEEEE--------EEEEEEE------EEEEEE----------------EEEE-------EEEEE---------EEEE------------------EE-----EEEE------------------------EEEEEEE--------EEEE-----EE--EEEEE---------EEEEEE---------EEEEEEE-------EEE----------------------------------------------EEEEEE-------EEEEEE---------------------EEEEEEEE----------EEEEEE-------EEEEEEEE--------EEEEE------------EEEEEEE------EEEEEE--------------------EEEEEEEEEE---------EEEEEEEE------EEEEEEE-----</code>