Difference between revisions of "KSH 0611 Review Epigenetic modifications regulate gene expression"
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Revision as of 01:13, 11 June 2016
Contents
Epigenetics
Definition : Heritable changes in gene activity and expression that occur without alteration in DNA sequence
Epigenetic modifications are crucial for packaging and interpreting the genome
Two well-known epigenetic modifications
- Chemical modification to the cytosine residues of DNA (DNA methylation)
- Histone modification
The patterns of epigenetic modifications can serve as
- Epigenetic markers to represent gene activity and expression
- Epigenetic markers to represent chromatin state
