Difference between revisions of "Thoughts on Genomics"
imported>Sanzhar Aitbay (Created page with "<p>1) Define Genomics your own way after doing research on what genomes are and how we study.</p> <p> </p> <p> </p> <p>-Genomics is changing the paradigm of biology<...") |
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<p>1) Define Genomics your own way after doing research on what genomes are and how we study.</p> | <p>1) Define Genomics your own way after doing research on what genomes are and how we study.</p> | ||
| − | <p> | + | <p>Genomics is a study of a genome. While genome is a complete set of genes of an organism, including all modifications that structures responsible for gene maintenance can harbor </p> |
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<p>-Genomics is changing the paradigm of biology</p> | <p>-Genomics is changing the paradigm of biology</p> | ||
| − | <p> | + | <p>Indeed the way that NGS enabled scientist to approach the biological phenomena is magnificent. The breakthrough happened just 15-20 years ago, at the fruits of it are still to come. Cancer, aging , neurodegenerative diseases, stem cell research and particularly all other researches in the biological field are taking benefits from this breakthrough. And yes it can be said that paradigm has shifted. </p> |
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Revision as of 02:35, 17 June 2018
1) Define Genomics your own way after doing research on what genomes are and how we study.
Genomics is a study of a genome. While genome is a complete set of genes of an organism, including all modifications that structures responsible for gene maintenance can harbor
-Genomics is changing the paradigm of biology
Indeed the way that NGS enabled scientist to approach the biological phenomena is magnificent. The breakthrough happened just 15-20 years ago, at the fruits of it are still to come. Cancer, aging , neurodegenerative diseases, stem cell research and particularly all other researches in the biological field are taking benefits from this breakthrough. And yes it can be said that paradigm has shifted.
2) What is the origin of genomics?
-The genomics by Darwin & Mendel
- Through Mendel's Cross experiment, we could know about how phenotype is inherited or transfered to their outsprings.
3) History of genomics?
- Darwin>Mendel > 3D Proteins > Cloning, Recombination > Amplification Technologies > Human Reference Genome > Next Gen. Sequencing/Personal Genomics > Synthetic Biology > Genome Engineering
4) The future of genomics?
-The future genomic technologies allow clinicians and biomedical researchers to drastically increase the amount of genomic data collected on large study populations.
5) What is the relationship with other omics?
The related suffix -ome is used to address the objects of study of such fields, such as the genome, proteome or metabolome respectively. The suffix -ome as used in molecular biology refers to a totality of some sort; similarly omics has come to refer generally to the study of large, comprehensive biological data sets. While the growth in the use of the term has led some scientists to claim that it has been oversold, it reflects the change in orientation towards the quantitative analysis of complete or near-complete assortment of all the constituents of a system
6) How can we engineer genomes?
It alters the genetic make-up of an organism using techniques that remove heritable material or that introduce DNA prepared outside the organism either directly into the host or into a cell that is then fused or hybridized with the host.This involves using recombinant nucleic acid techniques to form new combinations of heritable genetic material followed by the incorporation of that material either indirectly through a vector system or directly through micro-injection, macro-injection and micro-encapsulation techniques.
