Difference between revisions of "2017.06.02 YS"
From Biolecture.org
imported>Yeonsong Choi (Created page with "<ul> <li>Marker</li> <li>SNP(Single Nucleotide Polymorphism)</li> </ul> <p style="margin-left: 40px;">⇒ is a variation in a single <a href="https://en.wikipedia.org/...") |
imported>Yeonsong Choi |
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| − | <p style="margin-left: 40px | + | <p style="margin-left:40px">⇒ is a variation in a single <a href="https://en.wikipedia.org/wiki/Nucleotide" title="Nucleotide">nucleotide</a> that occurs at a specific position in the <a href="https://en.wikipedia.org/wiki/Genome" title="Genome">genome</a>, where each variation is present to some appreciable degree within a population.[1]</p> |
| − | <p style="margin-left: 40px | + | <p style="margin-left:40px">⇒ 한개의 염기서열이 바뀐 부분을 말한다</p> |
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| − | <p style="margin-left: 40px | + | <p style="margin-left:40px">⇒ Transcription : reflection (mirror) / DNA → RNA</p> |
| − | <p style="margin-left: 40px | + | <p style="margin-left:40px">⇒ Translation : make different / 3 base pair(codon) → 1 Amino acid</p> |
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| − | <p style="margin-left: 40px | + | <p style="margin-left:40px">⇒ 가장 큰 차이점은 oxygen</p> |
| − | <p style="margin-left: 40px | + | <p style="margin-left:40px">⇒ DNA는 oxygen이 없기때문에 stable / RNA 는 oxygen이 존재함</p> |
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| − | <p style="margin-left: 40px | + | <p style="margin-left:40px">protein A : stable mRNA, transcribe 5</p> |
| − | <p style="margin-left: 40px | + | <p style="margin-left:40px">protein B : unstable mRNA, transcribe 100</p> |
| − | <p style="margin-left: 40px | + | <p style="margin-left:40px">⇒ answer is A</p> |
| − | <p style="margin-left: 40px | + | <p style="margin-left:40px"> stable 한 mRNA가 cell 내에 더 오래 머물기 때문에 더 많은 protein을 만든다. </p> |
| − | <p style="margin-left: 40px | + | <p style="margin-left:40px"><img alt="" src="/ckfinder/userfiles/images/%EA%B7%B8%EB%A6%BC.png" style="height:150px; width:300px" /></p> |
| − | <p style="margin-left: 40px | + | <p style="margin-left:40px">blue is A , red is B</p> |
<ul> | <ul> | ||
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<p>[1] https://en.wikipedia.org/wiki/Single-nucleotide_polymorphism</p> | <p>[1] https://en.wikipedia.org/wiki/Single-nucleotide_polymorphism</p> | ||
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| + | <hr /> | ||
| + | <p><strong><a href="http://biolecture.org/index.php/Lecture_YS" title="Lecture YS">Lecture_YS</a></strong></p> | ||
Latest revision as of 16:57, 6 June 2017
- Marker
- SNP(Single Nucleotide Polymorphism)
⇒ is a variation in a single nucleotide that occurs at a specific position in the genome, where each variation is present to some appreciable degree within a population.[1]
⇒ 한개의 염기서열이 바뀐 부분을 말한다
- Functional genomics
- Transcription / Translation
⇒ Transcription : reflection (mirror) / DNA → RNA
⇒ Translation : make different / 3 base pair(codon) → 1 Amino acid
- DNA / RNA
⇒ 가장 큰 차이점은 oxygen
⇒ DNA는 oxygen이 없기때문에 stable / RNA 는 oxygen이 존재함
- Which protein make more in cell?
protein A : stable mRNA, transcribe 5
protein B : unstable mRNA, transcribe 100
⇒ answer is A
stable 한 mRNA가 cell 내에 더 오래 머물기 때문에 더 많은 protein을 만든다.
blue is A , red is B
- Hidden markov model (HMM)
- RNA는 environment change에 따라 차이가 있으니까 연구에 활용 가능할 듯.
[1] https://en.wikipedia.org/wiki/Single-nucleotide_polymorphism
