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<p>9/23 question</p>
<pstyle="margin-left: 40px;">Regarding phylogenetic tree</p>
<pstyle="margin-left: 40px;">My question: How can we know the divergence time?</p>
<pstyle="margin-left: 40px;">-> We cannot know the exact divergence time so this tree can be wrong.</p>
<pstyle="margin-left: 40px;"> We can just compare their genes and roughly estimate it by their genetic difference.</p>
<pstyle="margin-left: 40px;">Also we can use fossil record.</p>
<pstyle="margin-left: 40px;"> </p>
<p style="margin-left: 40px;">Jhong said it is a good question.</p> <p style="margin-left: 40px;"> </p> <p>10/8 2 questions</p>
<p>Regarding DNA sequencing</p>
<pstyle="margin-left: 40px;">My question: How do we know whether the sequence is right or wrong by linking fragments?</p> <p style="margin-left: 40px;">-> 1.Sequence genome multiple times to reduce error.</p> <p style="margin-left: 40px;">2. Experimentally we can seperate each DNA in a well then we know certain fragemnts are come from 1 DNA. And linking them.</p>
<pstyle="margin-left: 40px;">->nbsp; 1.Sequence genome multiple times to reduce error.</p>
<pstyle="margin-left: 40px;">2. Experimentally we can seperate each DNA in Jhong said it is a well then we know certain fragemnts are come from 1 DNA. And linking themgood question.</p>
<pstyle="margin-left: 40px;">My question: When using second method, we can know that they are all in one line but how can we control the distance between each fragment? </p>
<p>style="margin->left: 40px; By ">My question: When using long sequencesecond method, computer we can link them easily know that they are all in one line but if it is not, how can we can do pair-end sequencing.control the distance between each fragment?</p>
<pstyle="margin-left: 40px;">-> By using long scaffold and fill the gap. If the gaps fill sequence, computer can link them easily, it means but if it is accurate. Alsonot, compare with other species's genome by using CEGMA or BUSCOwe can do pair-end sequencing.</p>
<pstyle="margin-left: 40px;">By using long scaffold and fill the gap. If the gaps fill easily, it means it is accurate. Also, compare with other species's genome by using CEGMA or BUSCO.</p> <p style="margin-left: 40px;"> </p> <p style="margin-left: 40px;">Jhong said it is a good question.</p> <p style="margin-left: 40px;"> </p>
<p>10/14 Question and answering</p>
<pstyle="margin-left: 40px;">Regarding the question that 'what topic or question would you make relating with vulture genomics?'</p>
<pstyle="margin-left: 40px;">My answer: their digestive system, which can digest rotten meat. Also their habitat because they can live in harsh environment.</p>
<pstyle="margin-left: 40px;">My question: If we inject certain genes to different species, that species can get same property that we inject? </p>
<p>style="margin->left: 40px; It can">Jhong said their digestive system could be good topic. BecauseIn case of habitat, most of sequence it also can be a topic but is similar although they are different speciesnot much related with human.</p>
<pstyle="margin-left: 80px;"> </p> <p style="margin-left: 40px;">My question: If we inject certain genes to different species, that species can get same property that we inject?</p> <p style="margin-left: 40px;">-> It can. Because, most of sequence is similar although they are different species.</p> <p style="margin-left: 40px;"> </p>
<p>10/28 Question</p>
<pstyle="margin-left: 40px;">Regarding oncomics, after seeing the data about genome squencing .</p>
<pstyle="margin-left: 40px;">My question: 'Why men's cancer mortality is higher than women although Y chromosome does not occur mutation in that data? '</p>
<pstyle="margin-left: 40px;">-> In case of men, they have X, Y chromosomes so, it can be because their X chromosome is unstable. </p>
<pstyle="margin-left: 40px;">(However, this is different that I estimated in my essay that I already had written. But Jhong also said it is his guess.)</p>
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<p>11/11 2Answers</p>
<pstyle="margin-left: 40px;">Regarding telomere sequence, 'Why the sequence is TTAGGG?'</p> <p style="margin-left: 40px;">My Answer:</p>
<pstyle="margin-left: 40px;">It can be related with stop codon. Because, TAG among the T<strong>TAG</strong>GG sequence is stop codon and by using it as a template, <strong>My Answer:AAT</strong>CCC in different strand.</p>
<pstyle="margin-left: 40px;">It can be related with stop codon. BecauseSo, TAG among by the T<strong>TAG</strong>GG sequence opposite direction, TAA is also stop codon and by using it as a template, <strong>AAT</strong>CCC in different strand.</p>
<pstyle="margin-left: 40px;">So, by the opposite direction, TAA is also stop codon. </p>
<pstyle="margin-left: 40px;">Jhong said it is a good estimation. </p>
<pstyle="margin-left: 40px;">Regarding telomere length, in animal, if you have a longer telomere, it means die earlier. (By comparing mouse and human.) </p>
<pstyle="margin-left: 40px;">Regarding telomere length, in animal, if you have a longer telomere, it means die earlier. (By comparing mouse and human.) </p>
<pstyle="margin-left: 40px;">My answer:</p>
<pstyle="margin-left: 40px;">Although the telomere length is longer but the cell cycle time can be different.</p>
<pstyle="margin-left: 40px;"> </p>
<pstyle="margin-left: 40px;">Jhong siad it could be a reason because, they can die early if the cell cycle time is short eventhough they have longer telomere. </p>
<pstyle="margin-left: 40px;"> </p>
