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<div class="fm-title"><span style="font-size: large">Accurate Whole Human Genome Sequencing using Reversible Terminator Chemistry</span></div> <div class="fm-title">&nbsp;</div> <div class="contrib-group fm-author"><span style="font-size: x-small">David R. Bentley,¹ Shankar Balasubramanian,^2* Harold P. Swerdlow,^1&dagger; Geoffrey P. Smith,¹ John Milton,^1&sect; Clive G. Brown,^1&sect; Kevin P. Hall,¹ Dirk J. Evers,¹ Colin L. Barnes,^1,2 Helen R. Bignell,¹ Jonathan M. Boutell,¹ Jason Bryant,¹ Richard J. Carter,¹ R. Keira Cheetham,¹ Anthony J. Cox,¹ Darren J. Ellis,¹ Michael R. Flatbush,³ Niall A. Gormley,¹ Sean J. Humphray,¹ Leslie J. Irving,¹ Mirian S. Karbelashvili,³ Scott M. Kirk,³ Heng Li,⁴ Xiaohai Liu,^1,2 Klaus S. Maisinger,¹ Lisa J. Murray,¹ Bojan Obradovic,¹ Tobias Ost,¹ Michael L. Parkinson,¹ Mark R. Pratt,³ Isabelle M. J. Rasolonjatovo,¹ Mark T. Reed,³ Roberto Rigatti,¹ Chiara Rodighiero,¹ Mark T. Ross,¹ Andrea Sabot,¹ Subramanian V. Sankar,³ Aylwyn Scally,⁴ Gary P. Schroth,³ Mark E. Smith,¹ Vincent P. Smith,¹ Anastassia Spiridou,¹ Peta E. Torrance,¹ Svilen S. Tzonev,³ Eric H. Vermaas,³ Klaudia Walter,⁴ Xiaolin Wu,¹ Lu Zhang,³ Mohammed D. Alam,³ Carole Anastasi,¹ Ify C. Aniebo,¹ David M. D. Bailey,¹ Iain R. Bancarz,¹ Saibal Banerjee,³ Selena G. Barbour,¹ Primo A. Baybayan,³ Vincent A. Benoit,¹ Kevin F. Benson,¹ Claire Bevis,¹ Phillip J. Black,¹ Asha Boodhun,¹ Joe S. Brennan,¹ John A. Bridgham,³ Rob C. Brown,¹ Andrew A. Brown,¹ Dale H. Buermann,³ Abass A. Bundu,¹ James C. Burrows,³ Nigel P. Carter,⁴ Nestor Castillo,³ Maria Chiara E. Catenazzi,¹ Simon Chang,³ R. Neil Cooley,¹ Natasha R. Crake,¹ Olubunmi O. Dada,¹ Konstantinos D. Diakoumakos,¹ Belen Dominguez-Fernandez,¹ David J. Earnshaw,^1,2 Ugonna C. Egbujor,¹ David W. Elmore,³ Sergey S. Etchin,³ Mark R. Ewan,³ Milan Fedurco,⁵ Louise J. Fraser,¹ Karin V. Fuentes Fajardo,¹ W. Scott Furey,² David George,³ Kimberley J. Gietzen,⁶ Colin P. Goddard,¹ George S. Golda,³ Philip A. Granieri,³ David E. Green,¹ David L. Gustafson,³ Nancy F. Hansen,⁷ Kevin Harnish,¹ Christian D. Haudenschild,³ Narinder I. Heyer,¹ Matthew M. Hims,¹ Johnny T. Ho,³ Adrian M. Horgan,¹ Katya Hoschler,¹ Steve Hurwitz,³ Denis V. Ivanov,³ Maria Q. Johnson,³ Terena James,¹ T. A. Huw Jones,¹ Gyoung-Dong Kang,¹ Tzvetana H. Kerelska,³ Alan D. Kersey,¹ Irina Khrebtukova,³ Alex P. Kindwall,³ Zoya Kingsbury,¹ Paula I. Kokko-Gonzales,¹ Anil Kumar,¹ Marc A. Laurent,⁶ Cynthia T. Lawley,⁶ Sarah E. Lee,¹ Xavier Lee,³ Arnold K. Liao,³ Jennifer A. Loch,¹ Mitch Lok,³ Shujun Luo,³ Radhika M. Mammen,¹ John W. Martin,³ Patrick G. McCauley,¹ Paul McNitt,³ Parul Mehta,¹ Keith W. Moon,³ Joe W. Mullens,³ Taksina Newington,¹ Zemin Ning,⁴ Bee Ling Ng,⁴ Sonia M. Novo,¹ Michael J. O'Neill,³ Mark A. Osborne,^1,2 Andrew Osnowski,¹ Omead Ostadan,^3,6 Lambros L. Paraschos,³ Lea Pickering,¹ Andrew C. Pike,¹ Alger C. Pike,³ D. Chris Pinkard,³ Daniel P. Pliskin,³ Joe Podhasky,³ Victor J. Quijano,³ Come Raczy,¹ Vicki H. Rae,¹ Stephen R. Rawlings,¹ Ana Chiva Rodriguez,¹ Phyllida M. Roe,¹ John Rogers,¹ Maria C. Rogert Bacigalupo,¹ Nikolai Romanov,¹ Anthony Romieu,⁵ Rithy K. Roth,³ Natalie J. Rourke,¹ Silke T. Ruediger,¹ Eli Rusman,³ Raquel M. Sanches-Kuiper,¹ Martin R. Schenker,¹ Josefina M. Seoane,³ Richard J. Shaw,¹ Mitch K. Shiver,³ Steven W. Short,³ Ning L. Sizto,³ Johannes P. Sluis,³ Melanie A. Smith,¹ Jean Ernest Sohna Sohna,¹ Eric J. Spence,³ Kim Stevens,¹ Neil Sutton,¹ Lukasz Szajkowski,¹ Carolyn L. Tregidgo,¹ Gerardo Turcatti,⁵ Stephanie vandeVondele,¹ Yuli Verhovsky,³ Selene M. Virk,³ Suzanne Wakelin,³ Gregory C. Walcott,³ Jingwen Wang,¹ Graham J. Worsley,¹ Juying Yan,³ Ling Yau,³ Mike Zuerlein,³ Jane Rogers,⁴ James C. Mullikin,⁷ Matthew E. Hurles,⁴ Nick J. McCooke,^1&Dagger; John S. West,³ Frank L. Oaks,³ Peter L. Lundberg,³ David Klenerman,^2* [[Richard Durbin]],⁴ and Anthony J. Smith¹</span></div> <div class="contrib-group fm-author">&nbsp;</div> <div class="fm-affl">^{<font size="2">1</font>}<span style="font-size: small">Illumina Cambridge Ltd., (Formerly Solexa Ltd) Chesterford Research Park, Little Chesterford, Nr Saffron Walden, Essex. CB10 1XL, UK</span></div> <div class="fm-affl"><span style="font-size: small">²Department of Chemistry, University of Cambridge, The University Chemical Laboratory, Lensfield Road, Cambridge, CB2 1EW, UK</span></div> <div class="fm-affl"><span style="font-size: small">³Illumina Hayward, (Formerly Solexa Inc) 23851 Industrial Bvld, Hayward, CA 94343, USA</span></div> <div class="fm-affl"><span style="font-size: small">⁴The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK</span></div> <div class="fm-affl"><span style="font-size: small">⁵Manteia Predictive Medicine S.A. Zone Industrielle, Coinsins, CH-1267, Switzerland</span></div> <div class="fm-affl"><span style="font-size: small">⁶Illumina Inc. ,Corporate Headquarters, 9883 Towne Centre Drive, San Diego, CA 92121, USA</span></div> <div class="fm-affl"><span style="font-size: small">⁷National Human Genome Research Institute, National Institutes of Health, 41 Center Drive, MSC 2132, 9000 Rockville Pike, Bethesda, MD 20892-2132, USA</span></div> <div id="FN1" class="fm-footnote"><span style="font-size: small">^*Inventors and founders of Solexa Ltd</span></div> <div id="FN2" class="fm-footnote"><span style="font-size: small">^&dagger;The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK</span></div> <div id="FN3" class="fm-footnote"><span style="font-size: small">^&sect;Oxford Nanopore Technologies, Begbroke Science Park, Sandy Lane, Kidlington. OX5 1PF</span></div> <div id="FN4" class="fm-footnote"><span style="font-size: small">^&Dagger;Pronota, NV, VIB Bio-Incubator, Technologiepark 4, B-9052 Zwijnaarde / Ghent, Belgium</span></div> <div id="cor1" class="fm-footnote"><span style="font-size: small">Correspondence and requests for materials should be addressed to David.R. Bentley (<span class="email-label">Email: </span></span><span class="e_id4842102"><a class="ext-reflink" href="mailto:dbentley@illumina.com"><span style="font-size: small">dbentley@illumina.com</span></a></span><span style="font-size: small"> <script language="JavaScript" type="text/javascript"><!-- try{initUnObscureEmail ("e_id4842102", '<a class="ext-reflink" href="' + reverseAndReplaceString('moc.animulli/ta/yeltnebd:otliam', '/at/', '@') + '">' + reverseAndReplaceString('moc.animulli/ta/yeltnebd', '/at/','@') + '</a>')}catch(e){} //--></script>)</span></div> <p><span style="font-size: small">&nbsp;</span></p>

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