Changes
From Biolecture.org
no edit summary
<p> Human genome project is a large scale research project. Its aim are defining DNA sequence of human, find genes and mapping genes in gemone. This project is done in 2004 and people found that human has 3 billion nucleotides and 20,500 genes.[https://en.wikipedia.org/wiki/Human_Genome_Project]</p>
<h1>Epigenomics and Phenomics</h1>
<h2h3>Epigenomics</h2h3>
<p> Epigenomics study the epigenetic molecule in a cell, which are DNA methylation, histone modification and RNA interference.</p>
<h3h4>Techniques</h3h4>
<h5>ChIp-chip</h5>
<p> ChIp-chip is a combined technique for chromatin immunoprecipitation and DNA microarray. It can detect interactions between proteins and DNA, especially DNA-binding proteins.[https://en.wikipedia.org/wiki/ChIP-on-chip]</p>
<h5>ChIp-seq</h5>
<p> ChIp-seq is another method for detecting DNA-binding protein sites, which is combination of chromatin immunoprecipitation and DNA sequencing.[https://en.wikipedia.org/wiki/ChIP-sequencing]</p>
<h5>Bisulfite sequencing</h5>
<p> Bisulfite sequencing is a technique for detecting DNA methylation pattern. The idea is coming from that bisulfite can change cytosine to uracil but can't change 5-methylcystosine. So by compairing orginal DNA and bisulfite-treated DNA, people can find DNA methylation pattern.[https://en.wikipedia.org/wiki/Bisulfite_sequencing]</p>
<h3>Phenomics</h3>
<p> Phenomics study the phenomenon of a organism in respond to gene mutation and environment change.</p>
<h1>Canceromics and Geromics</h1>
<p> </p>
