Changes
From Biolecture.org
no edit summary
<p class="MsoNormal" align="left"><span lang="EN-US">4-1 What is transcriptomics?</span><span lang="EN-US"><br />
</span></p>
<p class="MsoNormal" align="left"><span lang="EN-US">Transcriptomics is study to research transcriptome which means the set of all RNA molecules including mRNA, rRNA, tRNA, and other non-coding RNA transcribed in one cell or a population of cells.<o:p></o:p></span><span lang="EN-US"><br />
</span></p>
<p class="MsoNormal" align="left"><span lang="EN-US">4-2 Relationship between genomics and transcriptomics<o:p></o:p></span><span lang="EN-US"><br />
</span></p>
<p class="MsoNormal" align="left"><span lang="EN-US">Transcriptomics is bigdata which is role of transcriptomes and environment to transcript DNA of organisms. Result from DNA sequence which is known by Genomics, we can expect transcriptome. And if we know certain environment which organism transcript DNA, we can know more about DNA. So I think it is complementary relation.</span><span lang="EN-US"><br />
</span></p>
<p class="MsoNormal" align="left"><span lang="EN-US">4-3 What are mRNAs?<o:p></o:p></span><span lang="EN-US"><br />
</span></p>
<p class="MsoNormal" align="left"><span lang="EN-US">mRNA is a large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression. Following transcription of primary transcript mRNA (known as pre-mRNA) by RNA polymerase, processed, mature mRNA is translated into a polymer of amino acids: a protein, as summarized in the central dogma of molecular biology.</span><span lang="EN-US"><br />
</span></p>
<p class="MsoNormal" align="left"><span lang="EN-US">4-4 Relationship between Transcriptome and Proteome.<o:p></o:p></span><span lang="EN-US"><br />
</span></p>
<p class="MsoNormal" align="left"><span lang="EN-US">Transcriptome have information for translation to proteins and have ability to accomplish translation. So Transcriptomics is some kinds of prior task for study of proteomics. <o:p></o:p></span><span lang="EN-US"><br />
</span></p>
<p class="MsoNormal" align="left"><span lang="EN-US"> 4-5 What is UTR?<o:p></o:p></span><span lang="EN-US"><br />
</span></p>
<p class="MsoNormal" align="left"><span lang="EN-US">In molecular genetics, an untranslated region refers to either of two sections, one on each side of a coding sequence on a strand of mRNA. If it is found on the 5' side, it is called the 5' UTR (or leader sequence), or if it is found on the 3' side, it is called the 3' UTR (or trailer sequence).<o:p></o:p></span><span lang="EN-US"><br />
</span></p>
<p class="MsoNormal" align="left"><span lang="EN-US"> 4-6What is ncRNA?<o:p></o:p></span><span lang="EN-US"><br />
</span></p>
<p class="MsoNormal" align="left"><span lang="EN-US">A non-coding RNA (ncRNA) is a functional RNA molecule that is not translated into a protein. It can be regulation factor.</span><span lang="EN-US"><br />
</span></p>
<p class="MsoNormal" align="left"><span lang="EN-US">4-7What is poly A?<o:p></o:p></span><span lang="EN-US"><br />
</span></p>
<p class="MsoNormal" align="left"><span lang="EN-US" style="font-size:10.0pt;mso-bidi-font-size:11.0pt;line-height:
