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<p><font size="3">Genomics inevitably employs high performance computing and bioinformatics technologies.</font></p>
<p><span class="mw-headline"><font size="4"> </font></span></p>
<div v:shape="_x0000_s1026"><span style="FONTfont-SIZEsize: 32pt"><font color="#339966" size="5">"[[Genome sequencing is not Genomics]]"</font></span></div>
<p> </p>
<p><strong><span class="mw-headline"><font size="4">History of the field</font></span></strong></p>
<p><font size="3">At present there are 24 cyanobacteria for which a total genome sequence is available. 15 of these cyanobacteria come from the marine environment. These are six <em>Prochlorococcus</em><em>Synechococcus</em> strains, <em>Trichodesmium erythraeum</em> IMS101 and <em>Crocosphaera watsonii</em> [[WH8501. Several studies have demonstrated how these sequences could be used very successfully to infer important ecological and physiological characteristics of marine cyanobacteria. However, there are many more genome projects currently in progress, amongst those there are further <em>Prochlorococcus</em> and marine <em>Synechococcus</em> isolates, <em>Acaryochloris</em> and <em>Prochloron</em>, the N<sub>2</sub>-fixing filamentous cyanobacteria <em>Nodularia spumigena</em>, <em>Lyngbya aestuarii</em> and <em>Lyngbya majuscula</em>, as well as bacteriophages infecting marine cyanobaceria. Thus, the growing body of genome information can also be tapped in a more general way to address global problems by applying a comparative approach. Some new and exciting examples of progress in this field are the identification of genes for regulatory RNAs, insights into the evolutionary origin of photosynthesis, or estimation of the contribution of horizontal gene transfer to the genomes that have been analyzed.<sup id="_ref-Herrero_0" class="reference">[10]</sup></font></p>
<p><font size="4">[[Genome sequencing and genomics]]</font></p>
<p><span style="font-size: large"><strong><span class="mw-headline"><font size="4">See also</fontspan></spanstrong></strongspan></p>
<ul>
<li><font size="3">[[Pangenomics]] and [[Pangenome]]</font></li>
</ul>
<p> </p>
<p><span style="font-size: large"><strong><span class="mw-headline"><font size="4">References</fontspan></spanstrong></strongspan></p>
<ol class="references">
<li id="_note-0"><font size="3"><strong><a title="" href="http://en.wikipedia.org/wiki/Genomics#_ref-0">^</a></strong> Min Jou W, Haegeman G, Ysebaert M, Fiers W., Nucleotide sequence of the gene coding for the bacteriophage MS2 coat protein, Nature. 1972 May 12;237(5350):82-8 </font></li>
<li id="_note-1"><font size="3"><strong><a title="" href="http://en.wikipedia.org/wiki/Genomics#_ref-1">^</a></strong> Fiers W et al., Complete nucleotide-sequence of bacteriophage MS2-RNA - primary and secondary structure of replicase gene, Nature, 260, 500-507, 1976 </font></li>
<li id="_note-2"><font size="3"><strong><a title="" href="http://en.wikipedia.org/wiki/Genomics#_ref-2">^</a></strong> Sanger F, Air GM, Barrell BG, Brown NL, Coulson AR, Fiddes CA, Hutchison CA, Slocombe PM, Smith M., Nucleotide sequence of bacteriophage phi X174 DNA, Nature. 1977 Feb 24;265(5596):687-95 </font></li>
<li id="_note-3"><font size="3"><strong><a title="" href="http://en.wikipedia.org/wiki/Genomics#_ref-3">^</a></strong> <a class="external text" title="http://www.ncbi.nlm.nih.gov/genomes/VIRUSES/virostat.html" class="external text" rel="nofollow" href="http://www.ncbi.nlm.nih.gov/genomes/VIRUSES/virostat.html"><em>The Viral Genomes Resource</em>, NCBI Friday, 14 September, 2007</a></font></li> <li id="_note-4"><font size="3"><strong><a title="" href="http://en.wikipedia.org/wiki/Genomics#_ref-4">^</a></strong> <a class="external text" title="http://www.ncbi.nlm.nih.gov/genomes/static/gpstat.html" class="external text" rel="nofollow" href="http://www.ncbi.nlm.nih.gov/genomes/static/gpstat.html"><em>Genome Project Statistic</em>, NCBI Friday, 14 September, 2007</a></font></li> <li id="_note-5"><font size="3"><strong><a title="" href="http://en.wikipedia.org/wiki/Genomics#_ref-5">^</a></strong> <a class="external text" title="http://news.bbc.co.uk/1/hi/sci/tech/3760766.stm" class="external text" rel="nofollow" href="http://news.bbc.co.uk/1/hi/sci/tech/3760766.stm">BBC article <em>Human gene number slashed</em> from Wednesday, 20 October, 2004</a></font></li> <li id="_note-6"><font size="3"><strong><a title="" href="http://en.wikipedia.org/wiki/Genomics#_ref-6">^</a></strong> <a class="external text" title="http://www.cbse.ucsc.edu/news/2003/10/16/pufferfish_fruitfly/index.shtml" class="external text" rel="nofollow" href="http://www.cbse.ucsc.edu/news/2003/10/16/pufferfish_fruitfly/index.shtml">CBSE News, Thursday October 16, 2003</a></font></li> <li id="_note-7"><font size="3"><strong><a title="" href="http://en.wikipedia.org/wiki/Genomics#_ref-7">^</a></strong> <a class="external text" title="http://www.genome.gov/12511476" class="external text" rel="nofollow" href="http://www.genome.gov/12511476">NHGRI, pressrelease of the publishing of the dog genome</a></font></li> <li id="_note-McGrath"><font size="3"><strong><a title="" href="http://en.wikipedia.org/wiki/Genomics#_ref-McGrath_0">^</a></strong> <cite class="book" style="FONTfont-STYLEstyle: normal" class="book">Mc Grath S and van Sinderen D (editors). (2007). <em><a class="external text" title="http://www.horizonpress.com/phage" class="external text" rel="nofollow" href="http://www.horizonpress.com/phage">Bacteriophage: Genetics and Molecular Biology</a></em>, 1st ed., Caister Academic Press. <a class="external text" title="http://www.horizonpress.com/phage" class="external text" rel="nofollow" href="http://www.horizonpress.com/phage">ISBN 978-1-904455-14-1</a> .</cite><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=Bacteriophage%3A+Genetics+and+Molecular+Biology&rft.au=Mc+Grath+S+and+van+Sinderen+D+%28editors%29.&rft.edition=1st+ed.&rft.pub=Caister+Academic+Press&rft_id=http%3A%2F%2Fwww.horizonpress.com%2Fphage" class="Z3988"> </span></font></li> <li id="_note-Herrero"><font size="3"><strong><a title="" href="http://en.wikipedia.org/wiki/Genomics#_ref-Herrero_0">^</a></strong> <cite class="book" style="FONTfont-STYLEstyle: normal" class="book">Herrero A and Flores E (editor). (2008). <em><a class="external text" title="http://www.horizonpress.com/cyan" class="external text" rel="nofollow" href="http://www.horizonpress.com/cyan">The Cyanobacteria: Molecular Biology, Genomics and Evolution</a></em>, 1st ed., Caister Academic Press. <a class="external text" title="http://www.horizonpress.com/cyan" class="external text" rel="nofollow" href="http://www.horizonpress.com/cyan">ISBN 978-1-904455-15-8</a> .</cite></font><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=The+Cyanobacteria%3A+Molecular+Biology%2C+Genomics+and+Evolution&rft.au=Herrero+A+and+Flores+E+%28editor%29.&rft.edition=1st+ed.&rft.pub=Caister+Academic+Press&rft_id=http%3A%2F%2Fwww.horizonpress.com%2Fcyan" class="Z3988"><font size="3"> </font><br />
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<p><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=The+Cyanobacteria%3A+Molecular+Biology%2C+Genomics+and+Evolution&rft.au=Herrero+A+and+Flores+E+%28editor%29.&rft.edition=1st+ed.&rft.pub=Caister+Academic+Press&rft_id=http%3A%2F%2Fwww.horizonpress.com%2Fcyan" class="Z3988"><font size="5"><br />
Web links</font><br />
[http://en.wikipedia.org/wiki/Genomics Wikipedia Genomics link]<br />
