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Thoughts on Genomics

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<p>2) What is the origin of genomics?</p>
<p>&nbsp;</p> <p>&nbsp;</p> <p>-The Origin of genomics by Darwin &amp; Mendel</p> <p>for me lies in the mid of 20th century when Watson and Crick found the structure&nbsp;</p> <p>of&nbsp;</p> <p>-&nbsp;Through Mendel&#39;s Cross experiment, we could know about how phenotype DNA. I think that from that point it was getting clear that the information that passes through generations is inherited or transfered to their outspringsactually DNA.</p> <p>&nbsp;</p>
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<p>3) History of genomics?</p>
<p>&nbsp;</p> <p>&nbsp;<Watson/p> <p>&nbsp;-&nbsp;Darwin&gt;Mendel Crick&gt; 3D Proteins &gt; Cloning, Recombination &gt; Amplification Technologies &gt; Human Reference Genome &gt; Next Gen. Sequencing/Personal Genomics &gt; Synthetic Biology &gt; Genome&nbsp;Engineering</p> <p>- &nbspgt;</p> <p>&nbsp;</p> <p>&nbsp;</p> <p>&nbsp;Synthetic Biology</p>
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<p>4) The future of genomics?</p>
 
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<p>-The&nbsp;future&nbsp;genomic technologies allow clinicians and biomedical researchers to drastically increase the amount of genomic data collected on large study populations.</p>
<p>However, increasing the number of data from the population may not solve all the problems&nbsp; due to heterogeneity that some diseases harbor. Thus single cell sequencing is another branch that should and will have major breakthroughs&nbsp; that will help us understand genomes better.&nbsp;</p>
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<p>5) What is the relationship with other omics?</p>
<p>&nbsp;</p> <p>&nbsp;</p> <p>The related suffix -ome is used to address the objects of study of such fieldsomics studies are mainly focused on data analysis, such as thus the genome,&nbsp;proteome or&nbsp;metabolome respectively. The suffix -ome as tools and logic used in molecular biology refers to a totality of some sort; similarly omics has come to refer generally to the study of large, comprehensive biological data setsthese studies may be interchanged. While the growth in the use of the term has led some scientists to claim that it has been oversold, it reflects the change in orientation towards the quantitative analysis of complete or near-complete assortment of all the constituents of a system</p> <p>&nbsp;</p>
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<p>6) How can we engineer genomes?</p>
<p>Synthetic biology is the field that progressing and aiming on this particular question. Creating a genome from scratch seems incredible, however for me it is still the data the information that&nbsp;</p> <p>&nbsp;</p> <p>genomes have is more important rather than&nbsp;It alters the genetic make-up of an organism using techniques that remove heritable material place, whether it is a tube or that introduce DNA prepared outside the organism either directly into the host or into a cell that is then fused or hybridized with where the hostinformation was created.This involves using recombinant nucleic acid&nbsp; techniques to form new combinations of heritable genetic material followed by the incorporation of that material either indirectly through a vector system or directly through micro-injection, macro-injection and micro-encapsulation techniques.</p>

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