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<p><strong>Introduction</strong></p>
<p><img alt="" src="/ckfinder/userfiles/images/NHGRI_human_male_karyotype(1).png" style="height:150px; width:191px" /> (Figure of Human Chromosomes)</p>
<p>Chromosome is a complex of each DNA molecule and its associated proteins. This is conserved form for prokaryotic and eukaryotic cells, and even for viruses. DNA is packaged into a chromosome to compact the large information and protect DNA from damage. Every cell maintains a characteristic number of chromosomes. One thing I was interested in was the genome size and gene density, because they are closely related to the organism complexity. The other thing was the shape of the packed genome, chromosomes. The chromosomes are all in the same human being, but they all looks different. However, I couldn't find the reason why their shape is not same to each other. Thus, I tried to figure it out and made a hypothesis. The shape of chromosomes is different because of the evolution.</p>
<p><strong>Result</strong></p>
<p><img alt="" src="/ckfinder/userfiles/images/LIWEEbYBcWWEQCTRKUAAAJaZ.png" style="height:200px; width:586px" /> (Overview of Chromosomes of Human GRCh38p.10)</p>
<p>The basic means of my model is just calculating the proportion of length of p-arm in every human chromosomes. Their shapes are different as the location of centromere varies, where the p-arm and q-arm are separated. I found a figure of overview of whole genome as chromosome from Ensembl. It shows the exact location of centromere so it was easy to check where the p-arm is and to analyze the data.</p>